Results 101 to 110 of about 768,829 (307)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Values congruence and commitment: throwing the role of psychological climate into the mix

open access: yes, 2012
Studying the fit between employees and their organisations and the individual and organisational outcomes of this congruence has been an interesting topic for researchers over the past decades. However, the literature does not adequately address how this
Abdelmoteleb, Samir
core  

Person-environment fit: A cross-national and cross-temporal study of human adaptation to isolated and confined environments

open access: yes, 2020
While most studies using a Person-Environment (P-E) fit approach focus on commonplace work settings, the present study adopts this approach to explore an extreme and unusual setting; specifically, Antarctic research stations. People who had been deployed
Jaksic, C   +5 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

“Fit Check”: Testing a Model of Perceptions of Team Level Person-Group Fit

open access: yes, 2023
Teams are become a mainstay in nearly every sector of business. Teams are complex and evolve to meet the demands of their unique environments. One team structure growing in popularity is a multiteam system (MTS), a system comprised of multiple teams ...
Wentworth, Alexandria
core  

Person-organization fit and organizational identification as predictors of positive and negative work-home interactions [PDF]

open access: yes, 2014
Objectives: The aim of the presented research was to explore the links between complementary and supplementary dimensions of Person-Organization fit (P-O fit), organizational identification (OI) and negative (WHI-) versus positive (WHI+) work-home ...
Dorota Merecz   +3 more
core   +1 more source

The Major Depressive Disorder Hierarchy: Rasch Analysis of 6 items of the Hamilton Depression Scale Covering the Continuum of Depressive Syndrome.

open access: yesPLoS ONE, 2017
ObjectivesMelancholic features of depression (MFD) seem to be a unidimensional group of signs and symptoms. However, little importance has been given to the evaluation of what features are related to a more severe disorder. That is, what are the MFD that
Lucas Primo de Carvalho Alves   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Mismatch between entrepreneurs and their firms: the role of cognitive fit / misfit [PDF]

open access: yes
(WP 10/04 Clave pdf) This paper examines the relationship between cognitive fit/misfit, and burnout, satisfaction, and intentions to exit the firm in entrepreneurs.
JULIO ORLANDO DE CASTRO
core  

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