Results 81 to 90 of about 2,425,259 (299)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Reawakening perceived person organization fit and perceived person job fit: Removing obstacles organizational commitment [PDF]

open access: yesManagement Science Letters, 2020
Mochamad Soelton   +5 more
doaj   +1 more source

Application of person–organization fit to military veterans [PDF]

open access: yesOrganization Management Journal
Purpose – Human resource management professionals strive to establish a high person–organization (PO) fit when hiring, as doing so ultimately reduces turnover and increases employee performance outcomes.
Meliza Figueroa-Torres   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

رابطه‌ی ابعاد تناسب فرد- محیط با بروندادهای سازمانی در پرستاران بیمارستان‌های دولتی شهر اصفهان

open access: yesمدیریت اطلاعات سلامت, 2014
مقدمه: تناسب فرد با محیط کار در دنیای در حال تغییر امروز، تبدیل به یکی از دغدغه‌های اصلی مدیران شده است. آن‌چه حایز اهمیت است این است که در مدل تناسب فرد- محیط، افراد در سطوح مختلفی اعم از شغل، گروه کاری، سازمان و حرفه با سازمان خود هماهنگ می‌شوند.
Ali Nasery Mohamadabadi   +4 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Un processus itératif pour réduire l’impact de réponses aberrantes sur l’identification de patrons de réponses inappropriés

open access: yesMesure et Évaluation en Éducation, 2013
La présence de réponses aberrantes est habituellement détectée par l’utilisation d’indices d’ajustement permettant de déterminer si le patron de réponses est inapproprié par rapport aux caractéristiques du test.
David Magis   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Person-environment fit: work-related attitudes and behavioral outcomes in continuing care retirement communities [PDF]

open access: yes
Doctor of PhilosophyDepartment of Hospitality Management & DieteticsChihyung OkAcademics and practitioners alike have studied the concept of person-environment fit (P-E fit) during the last two decades.
Yen, Wen-Shen
core  

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