Results 91 to 100 of about 1,944 (186)

Exploring pathways of NO and H₂S signaling in metabolic depression:The case of anoxic turtles [PDF]

, 2021
In contrast to most vertebrates, freshwater turtles of the genera Trachemys and Chrysemys survive total oxygen deprivation for long periods of time. This remarkable tolerance makes them ideal August Krogh's model animals to study adaptions to survive ...
Bundgaard, Amanda, Fago, Angela, Jensen, Birgitte S., Jensen, Frank B.   +3 more
core   +1 more source

Effect of 3‐mercaptopyruvate sulfurtransferase (3‐MST) inhibitors on contractile responses in porcine coronary artery

British Journal of Pharmacology, Volume 182, Issue 22, Page 5453-5468, November 2025.
Background and Purpose Hydrogen sulphide (H2S) is synthesised endogenously through cystathionine β‐synthase (CBS), cystathionine γ‐lyase (CSE) and 3‐mercaptopyruvate sulfurtransferase (3‐MST). Although exogenous H2S is known to produce vasodilatation, the vascular effect of H2S produced through 3‐MST is unknown. In this study, we demonstrate the effect
Maha Almaheize, Sahar Alharthi, Patricia Hemp, Jennifer Mattos, Marcus van Leer, Michael Garle, Stephen Alexander, Richard Roberts   +7 more
wiley   +1 more source

Redox regulation of enzymes involved in sulfate assimilation and in the synthesis of sulfur-containing amino acids and glutathione in plants

Frontiers in Plant Science, 2022
Sulfur is essential in plants because of its presence in numerous molecules including the two amino acids, cysteine, and methionine. Cysteine serves also for the synthesis of glutathione and provides sulfur to many other molecules including protein ...
Linda de Bont, Natacha Donnay, Jérémy Couturier, Jérémy Couturier, Nicolas Rouhier   +4 more
doaj   +1 more source

Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2 [PDF]

Maturation of iron-sulfur proteins in eukaryotes is initiated in mitochondria by the core iron-sulfur cluster assembly (ISC) complex, consisting of the cysteine desulfurase sub-complex NFS1-ISD11-ACP1, the scaffold protein ISCU2, the electron donor ...
Freibert, S., Hoock, M., Krapoth, N., Lill, R., Linne, U., Murphy, B. , Oltmanns, J., Schulz, V., Schünemann, V., Steinhilper, R. , Welsch, S.   +10 more
core   +2 more sources

Antioxidative and anti-inflammatory actions of reactive cysteine persulfides

Journal of Clinical Biochemistry and Nutrition, 2021
Cysteine persulfide (CysSSH) and polysulfides (CysS[S] n H, n>1) are cysteine derivatives having sulfane sulfur atoms bound to cysteine thiol. Recent advances in the development of analytical methods for detection and quantification of persulfides and polysulfides have revealed the biological presence, in both prokaryotes and eukaryotes, of persulfide ...
Zhang, Tianli, Tsutsuki, Hiroyasu, Ono, Katushiko, Akaike, Takaaki, Sawa, Tomohiro   +4 more
openaire   +3 more sources

Alfalfa Transcription Factor MsNAC2a Orchestrates the Homeostasis of Salt Stress Responses via Reactive Oxygen Species Accumulation and Hydrogen Sulphide Depletion

Plant Biotechnology Journal, Volume 23, Issue 11, Page 5297-5320, November 2025.
ABSTRACT Soil salinisation poses a significant threat to alfalfa (Medicago sativa L.) growth and development, limiting its productivity and hindering its widespread cultivation. Hydrogen sulphide (H2S) serves as an important gaseous signalling molecule in plants, mediating a myriad of physiological processes like salt tolerance.
Songchong Lu, Yan Sun, Zhaozi Wang, Wanting Yu, Ziyi Dong, Shikai Li, Lichao Ma, Kunlong Su, Huajie Zhang, Zeng‐Yu Wang, Juan Sun, Sheng Luan, Guofeng Yang   +12 more
wiley   +1 more source

Cardiac Arrest After Inhalation of Hazardous Gas Suspected Hydrogen Sulfide at Cucumber Pickle Factory: Two Case Reports

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT We report two cases of acute occupational exposure to hazardous gas, suspected to be hydrogen sulfide. The 34‐year‐old male and 48‐year‐old female patients worked as cleaners at a pickled cucumber factory. The two victims cleaned a waste tank (containing organic waste that can produce hydrogen sulfide) that had been abandoned for 2 years, with
Thi Bich Van Ha, Duc Lich Nguyen, Tat Luat Bui, Dinh Thanh Son Le, Na Le, Ngoc Anh Tran, Hong Thai Phan   +6 more
wiley   +1 more source

CSE/H2S/SESN2 Signalling Mediates the Protective Effect of Exercise Against Immobilization‐Induced Muscle Atrophy in Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Hydrogen sulphide (H2S), a gasotransmitter synthesized by cystathionine‐γ‐lyase (CSE), exhibits antioxidant properties and may mimic exercise‐induced muscle protection. However, its mechanistic role in muscle atrophy and exercise intervention remains unclear.
Xiuru Li, Yating Huang, Xuege Yang, Sujuan Liu, Yanmei Niu, Li Fu   +5 more
wiley   +1 more source

Mining proteomes for zinc finger persulfidation

RSC Chemical Biology
A meta-analysis of 22 persulfide-specific proteomics datasets reveals widespread persulfidation of zinc finger proteins across various species, highlighting the role of persulfidation as an important post-translational modification.
Haoju Li, Andrew T. Stoltzfus, Sarah L. J. Michel   +2 more
openaire   +2 more sources

Biosynthesis and Reactivity of Cysteine Persulfides in Signaling [PDF]

Journal of the American Chemical Society, 2015
Hydrogen sulfide (H2S) elicits pleiotropic physiological effects ranging from modulation of cardiovascular to CNS functions. A dominant method for transmission of sulfide-based signals is via posttranslational modification of reactive cysteine thiols to persulfides. However, the source of the persulfide donor and whether its relationship to H2S is as a
Pramod K, Yadav, Michael, Martinov, Victor, Vitvitsky, Javier, Seravalli, Rudolf, Wedmann, Milos R, Filipovic, Ruma, Banerjee   +6 more
openaire   +2 more sources