Results 41 to 50 of about 1,944 (186)

N-acetylcysteine serves as substrate of 3-mercaptopyruvate sulfurtransferase and stimulates sulfide metabolism in colon cancer cells [PDF]

, 2019
Hydrogen sulfide (H2S) is an endogenously produced signaling molecule. The enzymes 3-mercaptopyruvate sulfurtransferase (MST), partly localized in mitochondria, and the inner mitochondrial membrane-associated sulfide:quinone oxidoreductase (SQR), besides
Forte, Elena, Giardina, Giorgio, Giuffrè, Alessandro, Malagrinò, Francesca, Masi, Letizia, Paulini, Giulia, Tomé, Catarina S, Vicente, João B, Zuhra, Karim   +8 more
core   +2 more sources

Effects of inhibiting antioxidant pathways on cellular hydrogen sulfide and polysulfide metabolism [PDF]

, 2019
Elaborate antioxidant pathways have evolved to minimize the threat of excessive reactive oxygen species (ROS) and to regulate ROS as signaling entities.
Gao, Yan, Olson, Kenneth R.
core   +1 more source

Hydrogen sulfide-linked persulfidation of ABI4 controls ABA responses through the transactivation of MAPKKK18 in Arabidopsis [PDF]

, 2021
Hydrogen sulfide (H2S) is a signaling molecule that regulates plant hormone and stress responses. The phytohormone abscisic acid (ABA) plays an important role in plant adaptation to unfavorable environmental conditions and induces the persulfidation of L-
Fu, L., Gotor, Cecilia, Li, Z., Romero, Luis C., Shen J, Shen, W., Xie, Y., Yang, J., Yuan, X., Zhang, J., Zhao, Dan, Zhou H, Zhou, M.   +12 more
core   +1 more source

Acute hydrogen sulfide-induced neuropathology and neurological sequelae: challenges for translational neuroprotective research. [PDF]

, 2016
Hydrogen sulfide (H2 S), the gas with the odor of rotten eggs, was formally discovered in 1777, over 239 years ago. For many years, it was considered an environmental pollutant and a health concern only in occupational settings. Recently, however, it was
Anantharam, Poojya, Kanthasamy, Arthi, Kim, Dong-Suk, Rumbeiha, Wilson, Whitley, Elizabeth   +4 more
core   +1 more source

E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation. [PDF]

, 2022
Post-translational modifications by ubiquitin-like proteins (UBLs) are essential for nearly all cellular processes. Ubiquitin-related modifier 1 (Urm1) is a unique UBL, which plays a key role in tRNA anticodon thiolation as a sulfur carrier protein (SCP)
Brachmann, Cindy, Glatt, Sebastian, Grudnik, Przemysław, Guzman Perez, Sebastian, Jankowska, Urszula, Kaduhr, Lars, Krutyhołowa, Ros Cisław, Kwasna, Dominika, Kösters, Manuel, Leidel, Sebastian A, Lin, Sean, Ravichandran, Keerthiraju E, Schaffrath, Raffael, Shvetsova, Ekaterina, Skupien-Rabian, Bozena, Sokołowski, Mikołaj, Wilk, Piotr   +16 more
core   +1 more source

Reactions of isolated persulfides provide insights into the interplay between H2S and persulfide reactivity [PDF]

Free Radical Biology and Medicine, 2015
Hydrogen sulfide is ubiquitous in biological systems and exerts function over a wide range of important physiological processes. Complementing free H2S, the reductant-labile sulfur pool plays significant roles in the translocation and action of sulfide, however the chemistry of reductant-labile sulfide sources has not been studied systematically. Using
T Spencer, Bailey, Michael D, Pluth
openaire   +2 more sources

Biochemical properties of Paracoccus denitrificans FnrP:Reactions with molecular oxygen and nitric oxide [PDF]

, 2016
In Paracoccus denitrificans, three CRP/FNR family regulatory proteins, NarR, NnrR and FnrP, control the switch between aerobic and anaerobic (denitrification) respiration.
A Volbeda, A Yan, AJ Jervis, Andrew J. Thomson, AS Fleischhacker, B Weiss, B Zhang, CP Tseng, CT Przysiecki, CV Popescu, D Ralt, DJ Richardson, DJ Shaw, DM Bates, F Sievers, G Sawers, H Beinert, H Reents, J Crack, J Edwards, J Green, Jason C. Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Crack, JC Drapier, L Bergaust, LJ Moore, LR Bakken, M Matsui, Matthew I. Hutchings, MC Broillet, MF Otten, MI Hutchings, MI Hutchings, MM Bradford, N Filenko, Nick E. Le Brun, NJ Watmough, P Bouchal, PJ Kiley, R Bruckdorfer, R Veldman, RJ Spanning Van, RJ Spanning van, SA Ibrahim, SB Melville, ST Pullan, VR Sutton, WG Zumft, YM Kwon, YY Lee   +57 more
core   +1 more source

Label-Free Quantitative Proteomic Analysis of Nitrogen Starvation in Arabidopsis Root Reveals New Aspects of H₂S Signaling by Protein Persulfidation

Antioxidants, 2021
Hydrogen sulfide (H2S)-mediated signaling pathways regulate many physiological and pathophysiological processes in mammalian and plant systems.
Ana Jurado-Flores, Luis C. Romero, Cecilia Gotor   +2 more
doaj   +1 more source

Ap39, a mitochondria-targeting hydrogen sulfide (H2 s) donor, protects against myocardial reperfusion injury independently of salvage kinase signalling [PDF]

, 2017
Background and Purpose H2S protects myocardium against ischaemia-reperfusion injury. This protection may involve the cytosolic reperfusion injury salvage kinase (RISK) pathway, but direct effects on mitochondrial function are possible.
Baxter, Gary F., Boengler, Kerstin, Bornbaum, Julia, Karwi, Qutuba G., Schulz, Rainer, Torregrossa, Roberta, Whiteman, Matthew, Wood, Mark E.   +7 more
core   +1 more source

Possible molecular basis of the biochemical effects of cysteine-derived persulfides [PDF]

, 2022
Persulfides (RSSH/RSS−) are species closely related to thiols (RSH/RS−) and hydrogen sulfide (H2S/HS−), and can be formed in biological systems in both low and high molecular weight cysteine-containing compounds.
Benchoam, Dayana, Cuevasanta, Ernesto, Estrin, Darío A, Möller, Matías N., Semelak, Jonathan A., Trujillo, Madia, Zeida, Ari, Álvarez, Beatriz   +7 more
core   +3 more sources