A number of recent studies identified hydrogen sulfide (H2S) as an important signal in plant development and adaptation to environmental stress. H2S has been proven to participate in ethylene-induced stomatal closure, but how the signaling pathways of ...
Honglei Jia +11 more
doaj +1 more source
A role for the cystathionine-β-synthase /H2S axis in astrocyte dysfunction in the aging brain
Astrocytic dysfunction is central to age-related neurodegenerative diseases. However, the mechanisms leading to astrocytic dysfunction are not well understood.
Anindya Dey +11 more
doaj +1 more source
Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging
Protein persulfidation is a significant post-translational modification that involves addition of a sulfur atom to the cysteine thiol group and is facilitated by sulfide species.
Maria-Kyriaki Drekolia +9 more
doaj +1 more source
Metabolic and Structural Insights into Hydrogen Sulfide Mis-Regulation in Enterococcus faecalis
Hydrogen sulfide (H2S) is implicated as a cytoprotective agent that bacteria employ in response to host-induced stressors, such as oxidative stress and antibiotics.
Brenna J. C. Walsh +6 more
doaj +1 more source
A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems [PDF]
Protein Persulfide Detection Protocol reveals vital roles for thioredoxin and glutathione systems in maintaining sulfane sulfur homeostasis in cells and in vivo.
Éva Dóka +11 more
openaire +3 more sources
Novel roles of sulfur metabolism in stress‐controlled stomata aperture regulation
Summary Stomatal closure allows plants to conserve water by reducing transpiration during drought. Surprisingly, the assimilation of the macronutrient sulfur is intimately connected to the drought stress response. This Tansley insight will only briefly touch on the general impact of sulfate assimilation on the production of drought‐response metabolites.
Sheng‐Kai Sun +2 more
wiley +1 more source
Dietary restriction (DR) can increase protein persulfidation but the tissue specificity of this process is not well understood. Here, the authors compare organ-specific protein persulfidomes in young and aged mice under DR, and show that DR-dependent ...
Nazmin Bithi +8 more
doaj +1 more source
Hydrogen sulfide: A novel component in Arabidopsis peroxisomes which triggers catalase inhibition [PDF]
Plant peroxisomes have the capacity to generate different reactive oxygen and nitrogen species (ROS and RNS), such as H2O2, superoxide radical (O2 ), nitric oxide and peroxynitrite (ONOO- ).
Barroso, J.B. +4 more
core +1 more source
Hydrogen Sulfide and Reactive Oxygen Species, Antioxidant Defense, Abiotic Stress Tolerance Mechanisms in Plants [PDF]
Hydrogen sulfide (H2S), which was previously considered to be toxic, is now regarded as a burgeoning endogenous gaseous transmitter. H2S plays a vital role in the mechanism of response/adaptation to adverse environmental conditions as well as crosstalk ...
core +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source

