Results 71 to 80 of about 1,976 (189)

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, Volume 13, Issue 14, 9 March 2026.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

Is Encephalopathy a Mechanism to Renew Sulfate in Autism? [PDF]

, 2013
This paper makes two claims: (1) autism can be characterized as a chronic low-grade encephalopathy, associated with excess exposure to nitric oxide, ammonia and glutamate in the central nervous system, which leads to hippocampal pathologies and resulting
Ann Lauritzen, Beckham, Björck, Bourgeois, Brosnan, Choi, Cunningham, Davis, Esko, Frosini, Fulton, Hampton, Hashimoto, Heeney, Hoagland, Hoyumpa, Hsueh, James, Kimelberg, Lauri, Laurie Lentz-Marino, Lonsdale, Mak, McCully, Michalowicz, Misra, Moore, Mousain-Bosc, Nlu, Oller, Oury, Palková, Robert Davidson, Romero-Vives, Ross, Stephanie Seneff, Sturman, Vojdani, Watanabe   +38 more
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Exploring pathways of NO and H₂S signaling in metabolic depression:The case of anoxic turtles [PDF]

, 2021
In contrast to most vertebrates, freshwater turtles of the genera Trachemys and Chrysemys survive total oxygen deprivation for long periods of time. This remarkable tolerance makes them ideal August Krogh's model animals to study adaptions to survive ...
Bundgaard, Amanda, Fago, Angela, Jensen, Birgitte S., Jensen, Frank B.   +3 more
core   +1 more source

Characterization of a putative NsrR homologue in Streptomyces venezuelae reveals a new member of the Rrf2 superfamily [PDF]

, 2016
Members of the Rrf2 superfamily of transcription factors are widespread in bacteria but their functions are largely unexplored. The few that have been characterized in detail sense nitric oxide (NsrR), iron limitation (RirA), cysteine availability (CymR)
AR Tesson, B Grimm, B Gust, B Zhang, BJ Thompson, C Feehily, C Stuttard, C Trapnell, D Brekasis, DJ MacNeil, DJ Newman, EG Johnson, F Amman, FW Studier, G van Keulen, GL Challis, GL Newton, H Rodríguez, HD Youn, HK Lamb, HS Gill, J Crack, J Crack, J Hahn, J Lin, JC Crack, JD Partridge, JG Kang, JH Shin, JW Nicol, K Flärdh, Ka Datsenko, M Fujikawa, Ma Glazebrook, MA Gregory, ME Hibbing, MI Hutchings, MM Al-Bassam, MM Bradford, MMJ Couture, MS Kim, MT Forrester, P Jiang, PJ Stephens, PR Gardner, R Reja, RK Poole, S Chhabra, S Kimura, S Mishra, ST Pullan, SY Oh, TA Link, TL Bailey, WA Kibbe, Y Sasaki, YT Huang   +56 more
core   +1 more source

Iron‐Based Materials for Advanced Lithium/Sodium‐Ion Batteries

ChemSusChem, Volume 19, Issue 4, 25 February 2026.
This Review examines iron‐based anode materials for lithium‐ and sodium‐ion batteries, emphasizing how phase chemistry (sulfides, oxides, and metal–organic framework (MOF)‐derived compounds), multiscale structural engineering, and interface regulation collectively address volume expansion, conductivity limitations, and cycling instability, while ...
Jianfeng Hou, Xihan Tan, Honglei Zhang, Ning Han, Lei Jiang, Dechao Chen   +5 more
wiley   +1 more source

Critical Contribution of Nuclear Factor Erythroid 2-related Factor 2 (NRF2) to Electrophile-induced Interleukin-11 Production [PDF]

, 2017
Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that plays a crucial role in protection of cells from electrophile-induced toxicity through up-regulating phase II detoxifying enzymes and phase III transporters.
Deguchi Yutaka, Kojima Yuko, Kumagai Yoshito, Miura Ryosuke, Nakano Hiroyasu, Nishina Takashi, Okumura Ko, Shinkai Yasuhiro, Yamazaki Soh, 新開 泰弘, 熊谷 嘉人   +10 more
core   +2 more sources

Formation of persulfide groups in alkaline treated insulin [PDF]

FEBS Letters, 1970
Alkaline treatment of disulfidecontaining proteins is known to produce a number of unusual compounds related with the degradation of the cystinyl residues. Lanthionine [l] and lysinoalanine [2] are among the products identified with certainly, while dehydroala- nine [2] , thiocysteine [3,4] , cysteine sulfenic acid [S] and other products are supposed ...
Cavallini, D., Federici, G., Barboni, E., Marcucci, M.   +3 more
openaire   +2 more sources

Redox Signaling Regulated by Cysteine Persulfide and Protein Polysulfidation

Molecules, 2016
For decades, reactive persulfide species including cysteine persulfide (CysSSH) have been known to exist endogenously in organisms. However, the physiological significance of endogenous persulfides remains poorly understood. That cystathionine β-synthase
Shingo Kasamatsu, Akira Nishimura, Masanobu Morita, Tetsuro Matsunaga, Hisyam Abdul Hamid, Takaaki Akaike   +5 more
doaj   +1 more source

Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin, Chen Qian, Wenhao Li, Qihan Wang, Qifeng Sheng, Zheqing Chen, Wei Zhang, Wenming Li, Gaoran Ge, Zhanjun Yan, Dechun Geng   +10 more
wiley   +1 more source

Robocrystallographer: Automated crystal structure text descriptions and analysis [PDF]

, 2019
Our ability to describe crystal structure features is of crucial importance when attempting to understand structure-property relationships in the solid state. In this paper, the authors introduce robocrystallographer, an open-source toolkit for analyzing
Ganose, AM, Jain, A
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