Identification and full genome sequencing of previously unknown sandfly-borne phleboviruses using a newly established capture-based next-generation sequencing approach. [PDF]
Ogola EO +12 more
europepmc +1 more source
Recent progress in pig-to-human kidney xenotransplantation. [PDF]
Tao P, Zhou K.
europepmc +1 more source
Determination of the Copy Number of Porcine Endogenous Retroviruses (PERV) in Auckland Island Pigs Repeatedly Used for Clinical Xenotransplantation and Elimination of PERV-C. [PDF]
Fiebig U, Krüger L, Denner J.
europepmc +1 more source
Mitigating Cross-Species Viral Infections in Xenotransplantation: Progress, Strategies, and Clinical Outlook. [PDF]
Zhou Y, Zhou S, Wang Q, Zhang B.
europepmc +1 more source
Present Advances and Emerging Challenges in Kidney Xenotransplantation. [PDF]
Yamanaka K +10 more
europepmc +1 more source
Knockdown of porcine endogenous retrovirus (PERV) expression by PERV‐specific shRNA in transgenic pigs [PDF]
Abstract: Background: Xenotransplantation using porcine cells, tissues or organs may be associated with the transmission of porcine endogenous retroviruses (PERVs). More than 50 viral copies have been identified in the pig genome and three different subtypes of PERV were released from pig cells, two of them were able to infect human cells in vitro ...
Björn Petersen +2 more
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The origin of porcine endogenous retroviruses (PERVs)
Archives of Virology, 2021Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs, and they produce viral particles that are able to infect human cells and therefore pose a special risk for xenotransplantation. In contrast to other pig microorganisms that also pose a risk, such as porcine cytomegalovirus and hepatitis E virus, PERVs cannot be eliminated
openaire +2 more sources
Monitoring xenotransplant recipients for infection by PERV
Clinical Biochemistry, 2001Concerns have been raised over the possibility of transmission of porcine endogenous retrovirus (PERV) to porcine xenograft recipients.To help assess this risk, diagnostic assays capable of detection of an active, latent or cleared PERV infection, and the presence of pig cell microchimerism have been developed by a number of groups.
C, Herring +4 more
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Studies of the retroviruses have focused on the specific interaction of the nucleocapsid protein with a packaging signal in the viral RNA as important for this selectivity, but the packaging signal in porcine endogenous retrovirus (PERV) has not been defined.
Jiwon, Choi +8 more
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Mindful of their criticisms and committed to representing Australia's cultural diversity, the filmmakers blurred the boundaries of news, ethnographic documentary and media event broadcasting to transmit 'a multi-cam of an event that is happening', a truth of the parade.
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