Results 21 to 30 of about 148,335 (302)

PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging

Frontiers in Neuroscience, 2022
The development of novel PET imaging agents for synaptic vesicle glycoprotein 2A (SV2A) allowed for the in vivo detection of synaptic density changes, which are correlated with the progression and severity of a variety of neuropsychiatric diseases. While
Takuya Toyonaga, Arman Fesharaki-Zadeh, Arman Fesharaki-Zadeh, Stephen M. Strittmatter, Stephen M. Strittmatter, Richard E. Carson, Zhengxin Cai   +6 more
doaj   +1 more source

Simultaneous in vivo positron emission tomography and magnetic resonance imaging [PDF]

, 2008
Positron emission tomography (PET) and magnetic resonance imaging (MRI) are widely used in vivo imaging technologies with both clinical and biomedical research applications.
Catana, Ciprian, Cherry, Simon R., Jacobs, Russell E., Judenhofer, Martin S., Pichler, Bernd J., Procissi, Daniel, Qi, Jinyi, Wu, Yibao   +7 more
core   +2 more sources

Simultaneous in vivo PET/MRI using fluorine-18 labeled Fe3O4@Al(OH)3 nanoparticles: comparison of nanoparticle and nanoparticle-labeled stem cell distribution

EJNMMI Research, 2020
Background Mesenchymal stem cells (MSCs) have shown potential for treatment of different diseases. However, their working mechanism is still unknown. To elucidate this, the non-invasive and longitudinal tracking of MSCs would be beneficial.
Sarah Belderbos, Manuel Antonio González-Gómez, Frederik Cleeren, Jens Wouters, Yolanda Piñeiro, Christophe M. Deroose, An Coosemans, Willy Gsell, Guy Bormans, Jose Rivas, Uwe Himmelreich   +10 more
doaj   +1 more source

Novel ¹⁸F-Labeled PET Imaging Agent FV45 Targeting the Renin–Angiotensin System [PDF]

ACS Omega, 2018
Renin-angiotensin system (RAS) plays an important role in the regulation of blood pressure and hormonal balance. Using positron emission tomography (PET) technology, it is possible to monitor the physiological and pathological distribution of angiotensin II type 1 receptors (AT1), which reflects the functionality of RAS.
Xinyu Chen, Mitsuru Hirano, Rudolf A. Werner, Michael Decker, Takahiro Higuchi   +4 more
openaire   +4 more sources

Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions [PDF]

, 2015
The commercial availability of combined magnetic resonance imaging (MRI)/positron emission tomography (PET) scanners for clinical use has increased demand for easily prepared agents which offer signal or contrast in both modalities.
Al-Yassiry, M.M., Al-Yassiry, Mustafa M., Archibald, S.J., Archibald, Stephen J., Baghdadi, N., Baghdadi, Neazar, Burke, B.P., Burke, Benjamin P., Cawthorne, Christopher, Clemente, G.S., Clemente, Goncalo S., Clemente, Gonçalo S., Domarkas, Juozas, Gibbs, P., Gibbs, Peter, Kownacka, Alicja E., Lorch, Mark, Nigam, S., Nigam, Shubhanchi, Pickles, M., Pickles, Martin, Tripier, R., Tripier, Raphael, Tripier, Raphaël   +23 more
core   +2 more sources

Positron Emission Tomography Molecular Imaging of the Major Neurodegenerative Disorders: Overview and Pictorial Essay, from a Nuclear Medicine Center's Perspective

Journal of Integrative Neuroscience, 2023
Computed tomography (CT) and magnetic resonance imaging (MRI) provide key structural information on brain pathophysiology. Positron emission tomography (PET) measures metabolism in the living brain; it plays an important role in molecular neuroimaging ...
Ferdinando Calabria, Mario Leporace, Andrea Cimini, Maria Ricci, Laura Travascio, Antonio Bagnato   +5 more
doaj   +1 more source

A Novel Neutrophil-Specific PET Imaging Agent: cFLFLFK-PEG-⁶⁴Cu [PDF]

Journal of Nuclear Medicine, 2009
The synthesis and validation of a new, highly potent (64)Cu-labeled peptide, cFLFLFK-PEG-(64)Cu, that targets the formyl peptide receptor (FPR) on leukocytes is described. The peptide ligand is an antagonist of the FPR, designed not to elicit a chemotactic response resulting in neutropenia.
Landon W, Locke, Mahendra D, Chordia, Yi, Zhang, Bijoy, Kundu, Dylan, Kennedy, Jessica, Landseadel, Li, Xiao, Karen D, Fairchild, Stuart S, Berr, Joel, Linden, Dongfeng, Pan   +10 more
openaire   +2 more sources

Ultrasmall, elementary and highly translational nanoparticle X-ray contrast media from amphiphilic iodinated statistical copolymers

Acta Pharmaceutica Sinica B, 2023
To expand the single-dose duration over which noninvasive clinical and preclinical cancer imaging can be conducted with high sensitivity, and well-defined spatial and temporal resolutions, a facile strategy to prepare ultrasmall nanoparticulate X-ray ...
Lu Su, Kellie S. Dalby, Hannah Luehmann, Sussana A. Elkassih, Sangho Cho, Xun He, Lisa Detering, Yen-Nan Lin, Nari Kang, Dennis A. Moore, Richard Laforest, Guorong Sun, Yongjian Liu, Karen L. Wooley   +13 more
doaj   +1 more source

Positron Emission Tomography Probes for Imaging Cytotoxic Immune Cells

Pharmaceutics, 2022
Non-invasive positron emission tomography (PET) imaging of immune cells is a powerful approach for monitoring the dynamics of immune cells in response to immunotherapy.
Ala Amgheib, Ruisi Fu, Eric O. Aboagye
doaj   +1 more source

Stem Cell Imaging: Tools to Improve Cell Delivery and Viability. [PDF]

, 2016
Stem cell therapy (SCT) has shown very promising preclinical results in a variety of regenerative medicine applications. Nevertheless, the complete utility of this technology remains unrealized. Imaging is a potent tool used in multiple stages of SCT and
Jokerst, Jesse V, Wang, Junxin
core   +3 more sources