Results 101 to 110 of about 3,298 (171)

Lack of selection of antimalarial drug resistance markers after intermittent preventive treatment of schoolchildren (IPTsc) against malaria in northeastern Tanzania

International Journal of Infectious Diseases
Objective: Intermittent Preventive Treatment of schoolchildren (IPTsc) is recommended by WHO as a strategy to protect against malaria; to explore whether IPTsc with dihydroartemisinin-piperaquine (DP) or artesunate-amodiaquine (ASAQ) cause a selection of
Frederik Von Wowern, Geofrey Makenga, Sarah Wellmann Thomsen, Louise Wellmann Thomsen, Emma Filtenborg Hocke, Vito Baraka, Benjamin H. Opot, Daniel T.R. Minja, John P.A. Lusingu, Jean-Pierre Van-geertruyden, Helle Hansson, Michael Alifrangis   +11 more
doaj   +1 more source

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.

, 2016
BACKGROUND: The borders of Thailand harbour the world's most multidrug resistant Plasmodium falciparum parasites. In 1984 mefloquine was introduced as treatment for uncomplicated falciparum malaria, but substantial resistance developed within 6 years.

core   +1 more source

Selection signals in Ghana stratified by pairs who are IBD or non-IBD over Pfmdr1.

, 2018
Pairs that are IBD over Pfmdr1 represent the red signal while pairs that are not IBD over Pfmdr1 represent the black signal. The dashed horizontal line represent a 5% singificance threshold and the dashed vertical lines idenitfies the chromosome ...
Lyndal Henden (5253625), Stuart Lee (5264609), Ivo Mueller (46609), Alyssa Barry (124052), Melanie Bahlo (54258)   +4 more
core   +1 more source

Unraveling Key Chloroquine Resistance-Associated Alleles Among Plasmodium falciparum Isolates in South Darfur State, Sudan Twelve Years After Drug Withdrawal

Infection and Drug Resistance
Abdalmoneim M Magboul,1 Bakri YM Nour,2 Abdelhakam G Tamomh,1 Rashad Abdul-Ghani,3,4 Sayed Mustafa Albushra,5 Hanan Babiker Eltahir6 1Department of Parasitology & Medical Entomology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi,
Magboul AM, Nour BY, Tamomh AG, Abdul-Ghani R, Albushra SM, Eltahir HB   +5 more
doaj  

Frequency of Pfcrt 72-76 haplotype and Pfmdr1 N86Y SNP.

, 2013
A. Pfcrt 72-76 haplotype frequency per year; B. Pfmdr1 N86Y SNP frequency per year. Statistical significance was determined by Chi-square.
David Schnabel (584089), Edwin Kamau (282162), Elizabeth Wanja (584088), Norman C. Waters (584091), Hoseah M. Akala (584080), Ben Andagalu (584087), Charles Okudo (584084), Jacob D. Johnson (584092), Wallace Bulimo (584090), Luiser Ingasia (584081), Redemptah Yeda (584086), Douglas S. Walsh (257138), Angela Omondi (584083), Fredrick L. Eyase (584079), Agnes Cheruiyot (584082), Dennis Juma (584085)   +15 more
core   +1 more source

Proportion of Pfcrt 76K and 76T and pfmdr1 86N and 86Y haplotypes amongst children presenting with uncomplicated P. falciparum malaria from January 2002 to December 2007.

, 2013
T = pfcrt 76T, K = pfcrt 76K, Y = pfmdr1 86Y, N = pfmdr1 86N.
Johan Ursing (370814), Poul-Erik Kofoed (370815), Lars Rombo (370816), Amabelia Rodrigues (52773)   +3 more
core   +1 more source

Sequence Diversity of pfmdr1 and Sequence Conserve of pldh in Plasmodium falciparum from Indonesia: Its implications on Designing a Novel Antimalarial Drug with Less Prone to Resistance

Iranian Journal of Parasitology, 2013
Background: pfmdr1 and its variants are molecular marker which are responsible for antibiotics resistance in Plasmodium falciparum, a parasitic carrier for malaria dis-ease. A novel strategy to treat malaria disease is by disrupting parasite lactate dehy-
Muhamad Ali, Tetrawindu A Hidayatullah, Zulfikar Alimuddin, Yunita Sabrina   +3 more
doaj  

Molecular Surveillance of Antimalarial Drug Resistance-Associated Mutations in <i>P. falciparum</i> Imported from Africa into Guangdong Province, China, 2023-2025. [PDF]

Pathogens
Chen L, Mao Q, Wu, Liu J, Zhang J, Lu W, Peng M, Chen Y, Wang J, Chen J, Shi M.   +10 more
europepmc   +1 more source

Evolutionary diversity of the pfmdr1 hinge region and association with antimalarial drug resistance mutations post ACT introduction. [PDF]

Int J Parasitol Drugs Drug Resist
Hocke EF, Hansson H, Chopo-Pizarro A, Wellmann L, Kahunu GM, Mavoko HM, Nkoli PM, Sompwe EM, Mbongi D, Mitashi P, Ali IM, Nji A, Mbacham W, Moussiliou A, Dandonougbo C, Kpemasse A, Affoukou C, Akogbeto M, Ngufor C, Beshir K, Mousa A, Roper C, Sutherland CJ, Alifrangis M.   +23 more
europepmc   +1 more source

Changes in molecular markers of Plasmodium falciparum drug resistance between 2017 and 2024 in Southern Benin. [PDF]

Int J Parasitol Drugs Drug Resist
Bohissou FET, Nahum D, Inoue J, Sondo P, Hounsou L, Sondjo G, Djègbè NDC, Woli R, Dossou S, Kpohonnou C, Tinto H, Held J.   +11 more
europepmc   +1 more source