A Rapid Screening Strategy for Secondary Bacteriophages to Counter Phage Resistance in Carbapenem-Resistant <i>Acinetobacter baumannii</i>. [PDF]
Jiang RS, Chen LK, Tseng CC.
europepmc +1 more source
Abstract Early diagnosis of hepatocellular carcinoma (HCC) remains challenging because conventional serum biomarkers, especially alpha‐fetoprotein (AFP), show limited sensitivity for early‐stage disease. Recent progress in engineered molecular diagnostics provides new opportunities to improve HCC detection through integrated material, molecular, and ...
Jingzhi Xue +5 more
wiley +1 more source
Stepwise phage resistance and collateral phage susceptibility in <i>Klebsiella pneumoniae</i>. [PDF]
Yin X +6 more
europepmc +1 more source
Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu +3 more
wiley +1 more source
Intra-strain genomic microevolution and phage resistance in <i>Pseudomonas aeruginosa</i> PAO1 laboratory isolates. [PDF]
Washizaki A +5 more
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Biosensors enable rapid, sensitive, and portable detection of pathogens, contaminants, allergens, and food adulteration. Integration with smart packaging, smartphones, IoT, and machine learning supports real‐time monitoring and intelligent decision‐making, whereas microfluidics, biodegradable materials, explainable AI, and blockchain offer pathways ...
Mohima Akther Any +7 more
wiley +1 more source
Phenotypic heterogeneity shapes phage resistance and cocktail efficacy in <i>Klebsiella pneumoniae</i>. [PDF]
Mora-Quilis L +2 more
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This review offers an overview of recent advances in the fundamental properties, synthesis methods, and structural optimization of transition‐metal single‐atom electrocatalysts for electrochemical sensing. It also provides a comprehensive summary of the emerging applications in electrochemical assays based on these materials, along with key challenges ...
Yue Cao +8 more
wiley +1 more source
Smooth-to-rough morphotype alterations in <i>Mycobacterium abscessus</i> and their putative impact on phage resistance. [PDF]
Brosch R.
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Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li +7 more
wiley +1 more source

