Results 131 to 140 of about 150,978 (251)

Lifestyle-dependent evolution and CtrA-mediated lifestyle transitions shape phage resistance in marine Roseobacter. [PDF]

Nat Commun
Li C, Nair S, Zhang Z, Zhao J, Wang Z, Zhou C, Zhang R, Jiao N, Zhang Y.   +8 more
europepmc   +1 more source

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli: Tuning inclusion body architecture and protein yield via dissolved oxygen control

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil, Norma A Valdez‐Cruz, Sara Restrepo‐Pineda, Nuria Sánchez‐Puig, Rafael Vázquez‐Duhalt, Rubén D Cadena‐Nava, Néstor O Pérez, Mauricio A Trujillo‐Roldán   +7 more
wiley   +1 more source

A novel putative genus phage CW39: implications for CRISPR-Cas9-based phage resistance in <i>Streptomyces avermitilis</i>. [PDF]

Front Microbiol
Wen C, Wang Y, Wang L, Chen S.
europepmc   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Isolation of novel phages from a resistant Dorea longicatena strain reveals genes associated with phage resistance. [PDF]

Npj Viruses
Wang W, Li Z, Gondowardojo GR, Tan L, Wu C, Liu R, Xiao M, Liu C.   +7 more
europepmc   +1 more source

Mixed Litter Decomposition Drives Functional Gene Rearrangement in the Microbial Carbon Cycle

Land Degradation &Development, EarlyView.
ABSTRACT Understanding how mixed‐species litter decomposition regulates microbial communities and carbon cycling is vital for guiding ecosystem restoration and climate change mitigation, as it is a key process for nutrient cycling and carbon sequestration. A 15‐month field experiment compared single‐species (Pinus sylvestris var.
Jiaying Liu, Changjun Ding, Weixi Zhang, Xiaohua Su, Yawei Wei, Siqi Wu, Wenxu Zhu   +6 more
wiley   +1 more source

Immuno-phage synergy driven by fitness costs: turning bacterial phage resistance into therapeutic gain through evolutionary traps. [PDF]

Front Immunol
Fujiki J, Yamada A, Shinzato R, Hiya R, Norihisa N, Imai K, Wakabayashi E, Gondaira S, Higuchi H, Iwano H.   +9 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Isolation and characterization of phage vB_KpnS_SXK7 against multidrug-resistant Klebsiella pneumoniae and the mechanism of O-antigen-associated phage resistance. [PDF]

BMC Microbiol
Feng J, Sun L, Li Y, Zhang Y, Liang J, Wang R, Wang L, Meng Y, Yang Z, Cui X, Wu C, Jiao Z, Hou C.   +12 more
europepmc   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source