Results 151 to 160 of about 150,978 (251)

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Abiotic environmental conditions determine phage resistance outcomes in a salt-marsh bacterium. [PDF]

Philos Trans R Soc Lond B Biol Sci
Silk E, Harding K, Mahler M, Fineran PC, Meaden S.   +4 more
europepmc   +1 more source

Engineering Carbon Nanotube Quantum Well Defects With Recognition Tripeptides for Optical Detection of Extracellular Vesicles in Plasma

Small, EarlyView.
A three‐residue peptide bioconjugated onto a carbon nanotube quantum defect turns the near‐infrared emission of quantum defects into a reporter of integrins on intact extracellular vesicles, directly in human plasma. The sensor reveals that healthy fibroblast vesicles carry as much RGD‐binding integrin as cancer‐derived ones, an adhesion‐associated ...
In‐Jun Hwang, Junhee Kim, Aarti Patel, Leilei Zhang, Jacob Miller, Stanislav Piletsky, Cassandra L. Clift, Colin Hisey, YongJoo Kim, Mijin Kim   +9 more
wiley   +1 more source

Strengthening phage resistance of Streptococcus thermophilus by leveraging complementary defense systems. [PDF]

Nat Commun
Leprince A, Lefrançois J, Millen AM, Magill D, Horvath P, Romero DA, Rousseau GM, Moineau S.   +7 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Colanic acid-mediated phage resistance enhances virulence in high-risk global clone Escherichia coli ST410. [PDF]

PLoS Pathog
Tu J, Yang J, Song K, Wang J, Zhang N, He W, Liu J, Cai Z, Bai Y, Lv L, Zhu B, Tao P, Feng J, Liu JH.   +13 more
europepmc   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

Small Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo, Egor Kokin, Sangyul Baik, Chanyong Park, Minji Kim, Jeongmin Kim, Ryungeun Song, Hosub Lim   +7 more
wiley   +1 more source

Phage Resistance Modulates <i>Escherichia coli</i> B Response to Metal-Based Antimicrobials. [PDF]

Antibiotics (Basel)
Ezeanowai FC, Ewunkem AJ, Morikwe UC, Kiki LC, McGee LW, Graves JL, Jeffers-Francis LK.   +6 more
europepmc   +1 more source

Oral microbiome and homeostatic regulation of periodontal health: From dysbiosis to precision intervention

VIEW, EarlyView.
Periodontal homeostasis is maintained by coordinated interactions between the oral microbiome and host. Dysbiosis disrupts this ecological balance and contributes to periodontal disease, whereas multi‐omics, artificial intelligence, and microbiome‐based interventions provide emerging opportunities for precision diagnosis, ecological restoration, and ...
Xu Liu, Lei Meng, Wenzhu Song, Peiyu Wang, Bin Liu, Shihui Liu, Qi He, Bing Sun, Wanheng Li, Zhiwei Guan, Rui Dong, Qiang Feng   +11 more
wiley   +1 more source

Optical Density-Based Methods in Phage Biology: Titering, Lysis Timing, Host Range, and Phage-Resistance Evolution. [PDF]

Viruses
Abedon ST.
europepmc   +1 more source