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Phage Display Informatics [PDF]
Computational and Mathematical Methods in Medicine, 2013 Phage display is an efficient laboratory technique that can be used to screen for specific peptides and proteins displayed on the surface of bacteriophage. Since Professor George Smith of the University of Missouri pioneered the powerful and flexible method in 1980s [1], it has been adapted and improved by many scientists from various fields.
Huang, Jian +2 more
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SpyDisplay: A versatile phage display selection system using SpyTag/SpyCatcher technology
mAbs, 2023 Phage display is an established method for the in vitro selection of recombinant antibodies and other proteins or peptides from gene libraries. Here we describe SpyDisplay, a phage display method in which the display is achieved via SpyTag/SpyCatcher ...
Sarah-Jane Kellmann +6 more
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Advancement in the development of single chain antibodies using phage display technology [PDF]
PeerJPhage display technology has become an important research tool in biological research, fundamentally changing the traditional monoclonal antibody preparation process, and has been widely used in the establishment of antigen-antibody libraries, drug ...
Xiaohui Zheng +6 more
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Microorganisms, 2023 Amid the escalating challenges of antibiotic resistance, bacterial infections have emerged as a global threat. Bacteriophages (phages), viral entities capable of selectively infecting bacteria, are gaining momentum as promising alternatives to ...
Su Jin Jo +3 more
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Eliminating helper phage from phage display [PDF]
Nucleic Acids Research, 2006 Phage display technology involves the display of proteins or peptides, as coat protein fusions, on the surface of a phage or phagemid particles. Using standard technology, helper phage are essential for the replication and assembly of phagemid particles, during library production and biopanning. We have eliminated the need to add helper phage by using '
Chasteen, L. +3 more
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Selection of functional human antibodies from retroviral display libraries [PDF]
, 2004 Antibody library technology represents a powerful tool for the discovery and design of antibodies with high affinity and specificity for their targets.
Urban, Johannes H. +6 more
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Basics of Antibody Phage Display Technology
Toxins, 2018 Antibody discovery has become increasingly important in almost all areas of modern medicine. Different antibody discovery approaches exist, but one that has gained increasing interest in the field of toxinology and antivenom research is phage display ...
Line Ledsgaard +4 more
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Oligopeptide M13 Phage Display in Pathogen Research
Viruses, 2013 Phage display has become an established, widely used method for selection of peptides, antibodies or alternative scaffolds. The use of phage display for the selection of antigens from genomic or cDNA libraries of pathogens which is an alternative to the ...
Michael Hust +3 more
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Frontiers in Microbiology, 2022 The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody research and clinical development.
Ana S. André +7 more
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Generation of Lamprey Monoclonal Antibodies (Lampribodies) Using the Phage Display System. [PDF]
, 2019 The variable lymphocyte receptors (VLRs) consist of leucine rich repeats (LRRs) and comprise the humoral antibodies produced by lampreys and hagfishes.
Amemiya, Chris T +3 more
core +2 more sources