Results 11 to 20 of about 123,326 (328)
PhaTYP: Predicting the lifestyle for bacteriophages using BERT [PDF]
Briefings in Bioinformatics, November 2022, 2022 Bacteriophages (or phages), which infect bacteria, have two distinct lifestyles: virulent and temperate. Predicting the lifestyle of phages helps decipher their interactions with their bacterial hosts, aiding phages' applications in fields such as phage therapy.
arxiv +1 more source
Advanced Materials Interfaces, EarlyView., 2023 This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi +4 more
wiley +1 more source
Bacteriophage classification for assembled contigs using Graph Convolutional Network [PDF]
Bioinformatics, Volume 37, Issue Supplement1, July 2021, Pages
25-33, 2021 Motivation: Bacteriophages (aka phages), which mainly infect bacteria, play key roles in the biology of microbes. As the most abundant biological entities on the planet, the number of discovered phages is only the tip of the iceberg. Recently, many new phages have been revealed using high throughput sequencing, particularly metagenomic sequencing ...
arxiv +1 more source
Viruses in sanctuary chimpanzees across Africa
American Journal of Primatology, Volume 85, Issue 1, January 2023., 2023 Abstract Infectious disease is a major concern for both wild and captive primate populations. Primate sanctuaries in Africa provide critical protection to thousands of wild‐born, orphan primates confiscated from the bushmeat and pet trades. However, uncertainty about the infectious agents these individuals potentially harbor has important implications ...
Emily Dunay +9 more
wiley +1 more source
Generation of Lamprey Monoclonal Antibodies (Lampribodies) Using the Phage Display System. [PDF]
, 2019 The variable lymphocyte receptors (VLRs) consist of leucine rich repeats (LRRs) and comprise the humoral antibodies produced by lampreys and hagfishes.
Amemiya, Chris T +3 more
core +2 more sources
Statistical Methods for Estimating Complexity from Competition Experiments between Two Populations [PDF]
Journal of Theoretical Biology, Volume 264, Issue 3, 7 June 2010,
Pages 1043-1046, 2013 Often a screening or selection experiment targets a cell or tissue, which presents many possible molecular targets and identifies a correspondingly large number of ligands. We describe a statistical method to extract an estimate of the complexity or richness of the set of molecular targets from competition experiments between distinguishable ligands ...
arxiv +1 more source
Bacteriophage-mediated competition in Bordetella bacteria [PDF]
Proceedings of the Royal Society B: Biological Sciences (2006), 2005 Apparent competition between species is believed to be one of the principle driving forces that structure ecological communities, although the precise mecha nisms have yet to be characterized. Here we develop a model system that isolates phage-mediated interactions by neutralizing resource competition using two genetically identical Bordetella ...
arxiv +1 more source
Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites [PDF]
, 2012 The vast majority of anti-infective therapeutics on the market or in development are small molecules; however, there is now a nascent pipeline of biological agents in development.
Bishop-Hurley, Sharon L. +2 more
core +1 more source
Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022 Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem +6 more
wiley +1 more source
Construction and functional validation of combinatorial designed ankyrin repeat protein (DARPin) libraries for phage display [PDF]
, 2023 Designed ankyrin repeat protein (DARPin) is one of the most advanced alternative scaffold proteins. In this study, a combinatorial DARPin library for phage display was constructed.
Lappalainen, Matias
core