Generation of Lamprey Monoclonal Antibodies (Lampribodies) Using the Phage Display System. [PDF]
, 2019 The variable lymphocyte receptors (VLRs) consist of leucine rich repeats (LRRs) and comprise the humoral antibodies produced by lampreys and hagfishes.
Amemiya, Chris T +3 more
core +2 more sources
Frontiers in Microbiology, 2022 The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody research and clinical development.
Ana S. André +7 more
doaj +1 more source
Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: peach Pru p 3 allergen as a model. [PDF]
, 2008 Lipid transfer proteins (LTPs) are the major allergens of Rosaceae fruits in the Mediterranean area. Pru p 3, the LTP and major allergen of peach, is a suitable model for studying food allergy and amino acid sequences related with its IgE-binding ...
Compes, Esther +7 more
core +2 more sources
Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]
, 2007 A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar +54 more
core +1 more source
Landscape Phage: Evolution from Phage Display to Nanobiotechnology
Viruses, 2018 The development of phage engineering technology has led to the construction of a novel type of phage display library—a collection of nanofiber materials with diverse molecular landscapes accommodated on the surface of phage particles.
Valery A. Petrenko
doaj +1 more source
Development of anti-infectives using phage display: biological agents against bacteria, viruses, and parasites [PDF]
, 2012 The vast majority of anti-infective therapeutics on the market or in development are small molecules; however, there is now a nascent pipeline of biological agents in development.
Bishop-Hurley, Sharon L. +2 more
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An overview on application of phage display technique in immunological studies
Asian Pacific Journal of Tropical Biomedicine, 2017 Phage display is very strong technique in drug discovery and development. Phage display has many applications in improving the immunological studies. Development of monoclonal antibody, peptides, peptidomimetics and epitope mapping are main application ...
Abbas Rami +4 more
doaj +1 more source
Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates. [PDF]
, 2012 UnlabelledInvestigation of the human microbiome has revealed diverse and complex microbial communities at distinct anatomic sites. The microbiome of the human sebaceous follicle provides a tractable model in which to study its dominant bacterial ...
Bowman, Charles +13 more
core +2 more sources
Identification of Calpain Substrates by ORF Phage Display
Molecules, 2011 Substrate identification is the key to defining molecular pathways or cellular processes regulated by proteases. Although phage display with random peptide libraries has been used to analyze substrate specificity of proteases, it is difficult to deduce ...
Wei Li +2 more
doaj +1 more source
Deep Sequencing Analysis of Phage Libraries using Illumina Platform [PDF]
, 2014 This paper presents an analysis of phage-displayed libraries of peptides using Illumina. We describe steps for the preparation of short DNA fragments for deep sequencing and MatLab software for the analysis of the results.
Chu, Kiki +5 more
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