Results 21 to 30 of about 123,326 (328)

Mimotopes and Proteome Analyses Using Human Genomic and cDNA Epitope Phage Display [PDF]

, 2002
In the post-genomic era, validation of candidate gene targets frequently requires proteinbased strategies. Phage display is a powerful tool to define protein-protein interactions by generating peptide binders against target antigens.
Burge, Burton, Cabilly, Carcamo, Cochrane, Collins, Cortese, Evan, Fack, Fehrsen, Goldman, Hoogenboom, Hufton, Jacobsson, Jacobsson, Kunkel, Marks, Marks D. J., Mullaney, Mullaney, Mullaney P. B., Pallavicini G. M., Pereboeva, Robben, Santi, Schier, Scott, Xu, Yokota, Zozulya   +29 more
core   +3 more sources

Fabrication and Functionalisation of Nanocarbon‐Based Field‐Effect Transistor Biosensors

ChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022
Next‐generation diagnostics: Nanocarbon‐based field effect transistors (NC‐FETs) use incoming target analytes to impart a gating effect on conductance. Here, we review the operational mechanisms behind NC‐FETs, the fabrication and functionalisation of NC‐FETs with receptor biomolecules and downstream biosensing applications.
Chang‐Seuk Lee, Rebecca E. A. Gwyther, Mark Freeley, Dafydd Jones, Matteo Palma   +4 more
wiley   +1 more source

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar, Altschul, Arturo Talavera, Beales, Beckmann, Bosch, Burritt, Burritt, Clark, Cohen, Collins, Cuthbert, David I. Stott, de la Cruz, Delmastro, Ela M. Perez, Emini, Enshell-Seijffers, Felici, Folgori, Folgori, Frank Camacho, Gomara, Hollinger, Hoogenboon, Irving, Lemon, Lemon, Lemon, Lemon, Lemon, Lemon, Marston, Martin, Mattioli, Nainan, Neduva, Nevis Amin, Osmany G. Larralde, Partidos, Perea, Perez, Ping, Ping, Prezzi, Raiza Martinez, Reed, Sambrook, Scholfield, Stapleton, Stapleton, Stapleton, Verdaguer, Wan, Zhang   +54 more
core   +1 more source

Deep Sequencing Analysis of Phage Libraries using Illumina Platform [PDF]

, 2014
This paper presents an analysis of phage-displayed libraries of peptides using Illumina. We describe steps for the preparation of short DNA fragments for deep sequencing and MatLab software for the analysis of the results.
Chu, Kiki, Derda, Ratmir, Jin, Bingjie, Lee, Sam Whan, Matochko, Wadim L., Whitesides, George McClelland   +5 more
core   +1 more source

PhaBOX: A web server for identifying and characterizing phage contigs in metagenomic data [PDF]

published on Bioinformatics Advances 2023, 2023
Motivation: There is accumulating evidence showing the important roles of bacteriophages (phages) in regulating the structure and functions of the microbiome. However, lacking an easy-to-use and integrated phage analysis software hampers microbiome-related research from incorporating phages in the analysis.
arxiv  

Detection of hepatitis B virus core antigen by phage display mediated TaqMan real-time immuno-PCR [PDF]

, 2013
The core antigen (HBcAg) of hepatitis B virus (HBV) is one of the markers for the identification of the viral infection. The main purpose of this study was to develop a TaqMan real-time detection assay based on the concept of phage display mediated ...
Monjezi, Razieh, Sieo, Chin Chin, Tan, Sheau Wei, Tan, Wen Siang, Tey, Beng Ti   +4 more
core   +1 more source

PhaVIP: Phage VIrion Protein classification based on chaos game representation and Vision Transformer [PDF]

arXiv, 2023
Motivation: As viruses that mainly infect bacteria, phages are key players across a wide range of ecosystems. Analyzing phage proteins is indispensable for understanding phages' functions and roles in microbiomes. High-throughput sequencing enables us to obtain phages in different microbiomes with low cost. However, compared to the fast accumulation of
arxiv  

Phage display of proteins.

Acta Biochimica Polonica, 1998
In recent years the phage display approach has become an increasingly popular method in protein research. This method enables the presentation of large peptide and protein libraries on the surface of phage particles from which molecules of desired functional property(ies) can be rapidly selected.
Katarzyna Kościelska, Liliana Kiczak, Olga Wesołowska, Jacek Otlewski, Monika Kasztura   +4 more
openaire   +4 more sources

Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates. [PDF]

, 2012
UnlabelledInvestigation of the human microbiome has revealed diverse and complex microbial communities at distinct anatomic sites. The microbiome of the human sebaceous follicle provides a tractable model in which to study its dominant bacterial ...
Bowman, Charles, Cokus, Shawn, Fitz-Gibbon, Sorel, Hatfull, Graham F, Hayes, Clarmyra, Inkeles, Megan, Jacobs-Sera, Deborah, Kim, Jenny, Loncaric, Anya, Marinelli, Laura J, Miller, Jeff F, Modlin, Robert L, Pellegrini, Matteo, Russell, Daniel A   +13 more
core   +2 more sources

Understanding Biofilm-Phage Interactions in Cystic Fibrosis Patients Using Mathematical Frameworks [PDF]

arXiv, 2023
When planktonic bacteria adhere together to a surface, they begin to form biofilms, or communities of bacteria. Biofilm formation in a host can be extremely problematic if left untreated, especially since antibiotics can be ineffective in treating the bacteria.
arxiv