Mycotoxins, the small size secondary metabolites of fungi, have posed a threat to the safety of medicine, food and public health. Therefore, it is essential to create sensitive and effective determination of mycotoxins.
Wei Sun, Yan Zhang, Zhigang Ju
doaj +1 more source
Theranostic applications of phage display to control leishmaniasis: Selection of biomarkers for serodiagnostics, vaccination, and immunotherapy [PDF]
© 2015, Sociedade Brasileira de Medicina Tropical. All rights reserved. Phage display is a high-throughput subtractive proteomic technology used for the generation and screening of large peptide and antibody libraries.
Chávez-Fumagalli, Miguel A. +5 more
core +1 more source
Frameshifting in the P6 cDNA Phage Display System
Phage display is a powerful technique that enables easy identification of targets for any type of ligand. Targets are displayed at the phage surface as a fusion protein to one of the phage coat proteins.
Veerle Somers +3 more
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The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction [PDF]
Gene therapy has long been regarded as a promising treatment for cancer. However, cancer gene therapy is still facing the challenge of targeting gene delivery vectors specifically to tumors when administered via clinically acceptable non-invasive ...
Albahrani, M +5 more
core +2 more sources
Phage Display for the Generation of Antibodies for Proteome Research, Diagnostics and Therapy
Twenty years after its development, antibody phage display using filamentous bacteriophage represents the most successful in vitro antibody selection technology.
Michael Hust +4 more
doaj +1 more source
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies. [PDF]
Human cells express thousands of different surface proteins that can be used for cell classification, or to distinguish healthy and disease conditions.
Adams, Jarrett J +12 more
core +1 more source
Nanodiscs allow phage display selection for ligands to non-linear epitopes on membrane proteins. [PDF]
In this work, we exploited a method that uses polytopic membrane proteins as targets for phage display selections. Membrane proteins represent the largest class of drug targets and drug discovery is mostly based on the identification of ligands binding ...
Marina Pavlidou +3 more
doaj +1 more source
Selection of gonadotrophin surge attenuating factor phage antibodies by bioassay [PDF]
Peer reviewedPublisher ...
Fowler, Paul Alfred Francois +3 more
core +3 more sources
Cycle Sequencing of Filamentous Phage DNA Using a Biotinylated Primer and ΔTaq DNA Polymerase
We describe a rapid nonradioactive, double-stranded phage DNA sequencing method using ΔTaq DNA polymerase in cycle reaction for phage peptide-display library screening.
Jianping Qiu +3 more
doaj +1 more source
Phage display as a tool for identifying HIV-1 broadly neutralizing antibodies
Combinatorial biology methods offer a good solution for targeting interactions of specific molecules by a high-throughput screening and are widely used for drug development, diagnostics, identification of novel monoclonal antibodies, search for linear ...
A. N. Chikaev +3 more
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