Results 41 to 50 of about 123,326 (328)
Advanced Healthcare Materials, EarlyView.Segmented PCL‐bisurea (BU) polymers and BU‐peptide conjugate additives assemble into fibrous superstructures at the nanoscale through a mix‐and‐matching strategy. Different bioactivities are incorporated through variation of peptide sequences. The resulting materials are screened for their effect on stem cell adhesion and pluripotency.
Johnick F. van Sprang +6 more
wiley +1 more source
ELECTROPHORESIS, Volume 43, Issue 23-24, Page 2402-2427, December 2022., 2022 Abstract Nucleic acids are the blueprint of life. They are not only the construction plan of the single cell or higher associations of them, but also necessary for function, communication and regulation. Due to the pandemic, the attention shifted in particular to their therapeutic potential as a vaccine. As pharmaceutical oligonucleotides are unique in
Robert Minkner +3 more
wiley +1 more source
Diverse ATPase proteins in mobilomes constitute a large potential sink for prokaryotic host ATP [PDF]
arXiv, 2021 Prokaryote mobilome genomes rely on host machineries for survival and replication. Given that mobile genetic elements (MGEs) derive their energy from host cells, we investigated the diversity of ATP-utilizing proteins in MGE genomes to determine whether they might be associated with proteins that could suppress related host proteins that consume host ...
arxiv
Role of osmotic and hydrostatic pressures in bacteriophage genome ejection [PDF]
Phys. Rev. E 87, 022114 (2013), 2012 A critical step in the bacteriophage life cycle is genome ejection into host bacteria. The ejection process for double-stranded DNA phages has been studied thoroughly \textit{in vitro}, where after triggering with the cellular receptor the genome ejects into a buffer.
arxiv +1 more source
Efficient phage display of polypeptides fused to the carboxy-terminus of the M13 gene-3 minor coat protein [PDF]
, 2000 We report that, contrary to common belief, polypeptides fused to the carboxy-terminus of the M13 gene-3 minor coat protein are functionally displayed on the phage surface.
Fuh, Germaine, Sidhu, Sachdev S.
core +1 more source
Advanced Healthcare Materials, EarlyView.Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu +8 more
wiley +1 more source
Micro‐ and Nano‐Bots for Infection Control
Advanced Materials, EarlyView.This review presents a strategic vision for integrating micro‐ and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on ...
Azin Rashidy Ahmady +5 more
wiley +1 more source
Well-temperate phage: optimal bet-hedging against local environmental collapses [PDF]
Scientific Reports 5, Article number: 10523 (2015), 2013 Upon infection of their bacterial hosts temperate phages must chose between lysogenic and lytic developmental strategies. Here we apply the game-theoretic bet-hedging strategy introduced by Kelly to derive the optimal lysogenic fraction of the total population of phages as a function of frequency and intensity of environmental downturns affecting the ...
arxiv +1 more source
Advanced Materials, EarlyView.The CDs crosslinked egg white hydrogel loaded with lipopolysaccharide (LPS) and CA170 (TTF‐L‐C) can realize spatiotemporal tumor‐associated macrophages (TAMs) transformation from multi‐level dimensions, including spatial recruitment, cell phenotype reprogramming, and immune checkpoint molecule blockade.
Lingyun Li +8 more
wiley +1 more source
Hierarchy and extremes in selections from pools of randomized proteins [PDF]
, 2015 Variation and selection are the core principles of Darwinian evolution, yet quantitatively relating the diversity of a population to its capacity to respond to selection is challenging. Here, we examine this problem at a molecular level in the context of populations of partially randomized proteins selected for binding to well-defined targets. We built
arxiv +1 more source