Results 81 to 90 of about 82,683 (322)

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

What makes gouty inflammation so variable? [PDF]

open access: yes, 2017
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem.
Terkeltaub, Robert
core   +2 more sources

Selective Upregulation of Transcripts for Six Molecules Related to T Cell Costimulation and Phagocyte Recruitment and Activation among 734 Immunity-Related Genes in the Brain during Perforin-Dependent, CD8+ T Cell-Mediated Elimination of Toxoplasma gondii Cysts

open access: yesmSystems, 2020
We recently found that an invasion of CD8+ cytotoxic T cells into tissue cysts of Toxoplasma gondii initiates an elimination of the cysts in association with an accumulation of microglia and macrophages.
Jenny Lutshumba   +4 more
doaj   +1 more source

Lipid Peroxidation Activity and Immune Response in Modeling Inflammatory and Degenerative Damage to the Periodontium of Rats [PDF]

open access: yesInternational Journal of Biomedicine, 2019
The aim of this study was to assess changes in the lipid peroxidation activity and immune response in modeling inflammatory and degenerative damage to the soft tissues of the periodontium of Wistar rats.
Marina A. Darenskaya   +13 more
doaj   +1 more source

A Turing mechanism in order to explain the patchy nature of Crohn's disease [PDF]

open access: yesarXiv, 2020
Crohn's disease is an inflammatory bowel disease (IBD) that is not well understood. In particular, unlike other IBDs, the inflamed parts of the intestine compromise deep layers of the tissue and are not continuous but separated and distributed through the whole gastrointestinal tract, displaying a patchy inflammatory pattern.
arxiv  

Phagocytic Clearance in Neurodegeneration [PDF]

open access: yesThe American Journal of Pathology, 2011
The cellular and molecular mechanisms of phagocytic clearance of apoptotic cells and debris have been intensely studied in invertebrate model organisms and in the mammalian immune system. This evolutionarily conserved process serves multiple purposes.
Jennifer D. Sokolowski, James Mandell
openaire   +3 more sources

Advancing Chronic Wound Healing through Electrical Stimulation and Adipose‐Derived Stem Cells

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
Chronic cutaneous wounds represent significant challenges due to delayed healing and resistance to conventional treatments. This review explores the potential of combining adipose‐derived stem cells with electrical stimulation to enhance wound healing.
Qiuyue Peng   +5 more
wiley   +1 more source

History of Neuroscience: Mesoglia and Microglia [PDF]

open access: yes, 2007
Microglia are mononuclear phagocytes that reside within the central nervous system (CNS). They differ from macroglia (astrocytes and oligodendrocytes) in terms of their origin, phenotype and functions, but more closely resemble tissue-resident ...
Rezaie, Payam
core  

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Evolution and Conservation of Bordetella Intracellular Survival in Eukaryotic Host Cells

open access: yesFrontiers in Microbiology, 2020
The classical bordetellae possess several partially characterized virulence mechanisms that are studied in the context of a complete extracellular life cycle in their mammalian hosts.
Israel Rivera   +3 more
doaj   +1 more source

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