Results 51 to 60 of about 33,269 (261)
Frontiers in Immunology, 2018 Macrophages play a critical role in the elimination of fungal pathogens. They are sensed via cell surface pattern-recognition receptors and are phagocytosed into newly formed organelles called phagosomes.
Zeina Dagher +9 more
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The Coxiella burnetii T4SS Effector AnkF Is Important for Intracellular Replication
Frontiers in Cellular and Infection Microbiology, 2020 Coxiella burnetii is an obligate intracellular pathogen and the causative agent of the zoonotic disease Q fever. Following uptake by alveolar macrophages, the pathogen replicates in an acidic phagolysosomal vacuole, the C.
Julian Pechstein +8 more
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Wnt5A-Mediated Actin Organization Regulates Host Response to Bacterial Pathogens and Non-Pathogens
Frontiers in Immunology, 2021 Wnt5A signaling facilitates the killing of several bacterial pathogens, but not the non-pathogen E. coli DH5α. The basis of such pathogen vs. non-pathogen distinction is unclear.
Suborno Jati, Soham Sengupta, Malini Sen
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Phagosome Maturation: Steady as She Goes [PDF]
, 2005 Toll-like receptors (TLRs) trigger inflammatory signaling in macrophages and enrich on phagosomes, suggesting that TLRs may directly influence phagosome formation and maturation. However, in this issue of Immunity, Yates and Russell use carefully defined
Underhill, David M.
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Leishmania braziliensis: Strain-Specific Modulation of Phagosome Maturation
Frontiers in Cellular and Infection Microbiology, 2019 Leishmania (Viannia) braziliensis is responsible for the largest number of American tegumentary leishmaniasis (ATL) in Brazil. ATL can present several clinical forms including typical (TL) and atypical (AL) cutaneous and mucocutaneous (ML) lesions.
Tamara da Silva Vieira +7 more
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Frontiers in Immunology, 2023 Phagosome acidification and proteolysis are essential processes in the immune response to contain and eliminate pathogens. In recent years, there has been an increased desire for a rapid and accurate method of assessing these processes in real-time. Here,
Alba Méndez-Alejandre +4 more
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Regulatory Mechanism of SNAP23 in Phagosome Formation and Maturation [PDF]
Synaptosomal associated protein of 23 kDa (SNAP23), a plasma membrane-localized soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE), is a ubiquitously expressed protein that is generally involved in fusion of the plasma membrane
4929 +11 more
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Phagocytosis: Dynamin's Dual Role in Phagosome Biogenesis [PDF]
, 2008 SummaryDynamins have a well-established role in the fission of vesicles at sites of endocytosis. In phagocytosis, however, a role for certain dynamin isoforms has been reported in the full extension of pseudopods during phagosome formation, not in ...
Grinstein, Sergio, Huynh, Kassidy K.
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, 2020 Phagosome pathway as showed by the KEGG database. Proteins in the pathway are depicted by boxes while arrows depict signaling routes. Red stars correspond to modulated proteins, identified by the MS analysis, at 1HPLT ((Hours post LPS treatment), blue ...
Károly Vékey (122026) +8 more
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Frontiers in ImmunologyIntroductionTuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of mortality worldwide. A crucial factor in Mtb's virulence is the ESX-5 secretion system, which transports PE/PPE proteins such as PE18 and PPE26.
Aquib Ehtram +11 more
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