Results 1 to 10 of about 36,200 (145)
Intracellular pathogens have varied strategies to breach the endolysosomal barrier so that they can deliver effectors to the host cytosol, access nutrients, replicate in the cytoplasm, and avoid degradation in the lysosome.
Ekansh Mittal +7 more
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Lipid body-phagosome interaction in macrophages during infectious diseases: host defense or pathogen survival strategy? [PDF]
Phagocytosis of invading microorganisms by specialized cells such as macrophages and neutrophils is a key component of the innate immune response. These cells capture and engulf pathogens and subsequently destroy them in intracellular vacuoles-the ...
Rossana C N Melo, Ann M Dvorak
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In this study, haemocytes present in Papilio hyperbius Linnaeus were identified and characterized. Six different types of haemocyte were recorded in the haemocoel of this species of insect: prohaemocytes, plasmatocytes, granulocytes, spherulocytes ...
Min-Soo GO +6 more
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Tuberculosis control by novel vaccines development and Indian initiatives
Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is one of the worst microbial diseases of humankind and an awful societal problem, especially in underdeveloped countries.
Prasanta Kumar Ghosh
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Antimicrobial Activity of Neutrophils Against Mycobacteria
The mycobacterium genus contains a broad range of species, including the human pathogens M. tuberculosis and M. leprae. These bacteria are best known for their residence inside host cells.
Heather A. Parker +4 more
doaj +1 more source
Rab14 regulates the maturation of macrophage phagosomes containing the fungal pathogen Candida albicans and the outcome of the host-pathogen interaction [PDF]
Date of Acceptance: 02/02/2015 Copyright © 2015, American Society for Microbiology.
Bain, Judith M +4 more
core +6 more sources
Cx43-mediated hyphal folding counteracts phagosome integrity loss during fungal infection
Phagolysosomes are crucial organelles during the elimination of pathogens by host cells. The maintenance of their membrane integrity is vital during stressful conditions, such as during Candida albicans infection.
Beatriz Cristovao +6 more
doaj +1 more source
There is a limited understanding of host defense mechanisms targeting intracellular pathogens that proliferate in a lysosome. Coxiella burnetii is a model bacterial pathogen capable of replicating in the hydrolytic and acidic environment of the lysosome.
Sandhya Ganesan +5 more
doaj +1 more source
DRAM1 Promotes Lysosomal Delivery of Mycobacterium marinum in Macrophages
Damage-Regulated Autophagy Modulator 1 (DRAM1) is an infection-inducible membrane protein, whose function in the immune response is incompletely understood.
Adrianna Banducci-Karp +7 more
doaj +1 more source
Microbial pathogens exploit host nutrients to proliferate and cause disease. Intracellular pathogens, particularly those exclusively living in the phagosome such as Histoplasma capsulatum, must adapt and acquire nutrients within the nutrient-limited ...
Qian Shen +4 more
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