Results 21 to 30 of about 36,298 (238)

The Burkholderia pseudomallei type III secretion system and BopA are required for evasion of LC3-associated phagocytosis. [PDF]

PLoS ONE, 2011
Burkholderia pseudomallei is the causative agent of melioidosis, a fatal infectious disease endemic in tropical regions worldwide, and especially prevalent in southeast Asia and northern Australia.
Lan Gong, Meabh Cullinane, Puthayalai Treerat, Georg Ramm, Mark Prescott, Ben Adler, John D Boyce, Rodney J Devenish   +7 more
doaj   +1 more source

Proteomic analysis of Atg8-dependent recruitment of phagosomal proteins in the enteric protozoan parasite Entamoeba histolytica

Frontiers in Cellular and Infection Microbiology, 2022
Autophagy is one of the bulk degradation systems and is conserved throughout eukaryotes. In the enteric protozoan parasite Entamoeba histolytica, the causative agent of human amebiasis, Atg8 is not exclusively involved in autophagy per se but also in ...
Kumiko Nakada-Tsukui, Natsuki Watanabe, Kumiko Shibata, Ratna Wahyuni, Eri Miyamoto, Tomoyoshi Nozaki   +5 more
doaj   +1 more source

Mycobacterium tuberculosis Responds to Chloride and pH as Synergistic Cues to the Immune Status of its Host Cell [PDF]

, 2013
PubMed ID: 23592993This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Castaneda-Garcia, A Di, A Kumar, AL Radtke, AM Cooper, BE Steinberg, BP Cormack, CE Barry 3rd, CM Sassetti, D Wagner, David G. Russell, DE Voth, DG Russell, DG Russell, H Barriere, H Ohno, HC Mwandumba, HD Park, J Rengarajan, JC Antoine, JL Flynn, K Pethe, K von Bargen, KH Rohde, LE Via, MI Voskuil, ND Sonawane, ND Sonawane, Neelima Sukumar, P Carroll, P Golby, PM Haggie, RB Abramovitch, RJ North, RM Yates, Robert B. Abramovitch, S Sturgill-Koszycki, S Sturgill-Koszycki, SB Walters, Shumin Tan, SM Payne, T Soldati, T Stauber, Tanya Parish, TB Reddy, UE Schaible, V Faundez, W Epstein, William R. Bishai   +48 more
core   +8 more sources

Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]

, 2019
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron, Alvarez, Alvarez, Artavanis-Tsakonas, Bain, Ben-Abdallah, Bielska, Blackstock, Boya, Bryan, Burch, Chang, Charlier, Chen, Cheng, Chu, Circu, Cox, Davis, De Leon-Rodriguez, De Leon-Rodriguez, Denham, Di, Diamond, Doshi, Dragotakes, Drew, Erb-Downward, Erwig, Evans, Feldmesser, Franchi, Fu, Gilbert, Gordon, Guerra, Gustafson, Haka, Han, Henson, Heo, Hibbs, Hoag, Hommel, Huang, Hybiske, Iwasaki, Johnston, Kjos, Kleinschek, Kruskal, Kusner, Lei, Leopold Wager, Levitz, Levitz, Lim, Liu, Lévêque, Ma, Maderna, May, Milam, Mosser, Murdock, Murray, Myers, Müller, Nel, Nicola, Nunes, Okagaki, O’Meara, Pauwels, Qiu, Rajasingham, Russell, Samantaray, Santiago-Tirado, Singh, Smith, Stukes, Stukes, Swisher, Tucker, Vashi, Voelz, Vu, Vu, Walkey, Wang, Wang, Watkins, Weiss, Wormley, Wozniak, Yates, Yoshida, Zaragoza   +98 more
core   +2 more sources

N-Acetylglucosamine Metabolism Promotes Survival of Candida albicans in the Phagosome

mSphere, 2017
Phagocytosis by innate immune cells is one of the most effective barriers against the multiplication and dissemination of microbes within the mammalian host.
Elisa M. Vesely, Robert B. Williams, James B. Konopka, Michael C. Lorenz   +3 more
doaj   +1 more source

Human Monocyte-Derived Dendritic Cells Produce Millimolar Concentrations of ROS in Phagosomes Per Second

Frontiers in Immunology, 2019
Neutrophils kill ingested pathogens by the so-called oxidative burst, where reactive oxygen species (ROS) are produced in the lumen of phagosomes at very high rates (mM/s), although these rates can only be maintained for a short period (minutes).
Laurent M. Paardekooper, Ilse Dingjan, Ilse Dingjan, Peter T. A. Linders, Alexander H. J. Staal, Simona M. Cristescu, Wilco C. E. P. Verberk, Geert van den Bogaart, Geert van den Bogaart   +8 more
doaj   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross-Presentation. [PDF]

Eur J Immunol
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Senni A, Grumbach L, Ceccacci S, Frechin M, Goudin N, Guerrera IC, Bertocci B, van Endert P.   +7 more
europepmc   +2 more sources

Phagosome-lysosome fusion

Biochemical Society Transactions, 1986
Phagosome-lysosome fusion plays an important role in the destruction of micro-organisms by phagocytic cells. Several approaches have been used to study the determinants of phagosome-lysosome fusion in mouse macrophages. Fusion can be assayed by electron microscopy using horseradish peroxidase or thorium dioxide as a marker for secondary lysosomes or by
Gabay, JE, Horwitz, MA, Cohn, ZA
openaire   +4 more sources

Phagosome maturation: aging gracefully [PDF]

Biochemical Journal, 2002
Foreign particles and apoptotic bodies are eliminated from the body by phagocytic leucocytes. The initial stage of the elimination process is the internalization of the particles into a plasma membrane-derived vacuole known as the phagosome. Such nascent phagosomes, however, lack the ability to kill pathogens or to degrade the ingested targets.
Otilia V, Vieira, Roberto J, Botelho, Sergio, Grinstein   +2 more
openaire   +2 more sources

Monitoring the Recruitment and Fusion of Autophagosomes to Phagosomes During the Clearance of Apoptotic Cells in the Nematode Caenorhabditis elegans

Bio-Protocol, 2022
During an animal's development, a large number of cells undergo apoptosis, a suicidal form of death. These cells are promptly phagocytosed by other cells and degraded inside phagosomes.
Omar Peña-Ramos, Zheng Zhou
doaj   +1 more source