The ubiquitin-binding protein ANKRD13A mediates VCP-dependent mitochondrial outer membrane rupture during PINK1/Parkin-mediated mitophagy. [PDF]
Chu WH +8 more
europepmc +1 more source
Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes. [PDF]
Özel C +13 more
europepmc +1 more source
Receptor-mediated mitophagy: a new target of neurodegenerative diseases. [PDF]
Yang J +5 more
europepmc +1 more source
Targeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells
The acquisition of endocrine resistance is a common obstacle in endocrine therapy of patients with oestrogen receptor-α (ERα)-positive breast tumours. We previously demonstrated that the BIG3–PHB2 complex has a crucial role in the modulation of oestrogen/ERα signalling in breast cancer cells.
openaire
SLP2/PHB Aggregates in ALS Mouse Models and Patients: Implications Beyond CHCHD10-Associated Motor Neuron Disease. [PDF]
Genin EC +4 more
europepmc +1 more source
Towards a molecular understanding of mitochondrial prohibitin function [PDF]
Johann, Anna Elisabeth Alice
core
IGFBP6 orchestrates antiinfective immune collapse in murine sepsis via prohibitin-2-mediated immunosuppression. [PDF]
Chen K +13 more
europepmc +1 more source
Mitophagy in breast cancer: Regulatory mechanisms and therapeutic potential. [PDF]
Chang Y +9 more
europepmc +1 more source
Proteomic analysis of the inhibitory effect of epigallocatechin gallate on lipid accumulation in human HepG2 cells [PDF]
core +1 more source

