Results 101 to 110 of about 2,921 (152)

Cryo-EM structure of the prohibitin complex in open conformation. [PDF]

Proc Natl Acad Sci U S A
Hong S, Guan Z, Zhang L, Zhuang J, Yan L, Liu Y, Liu Z, Wang Q, Yin P.   +8 more
europepmc   +1 more source

A novel ligustrazine-based nanodelivery system protects against doxorubicin-induced cardiotoxicity by targeting the SIRT5-DUSP1 axis for mitochondrial repair. [PDF]

J Nanobiotechnology
Shi H, Pang B, Zhang F, Guo Z, Xu W, Zheng M, You Y, Liu G, Nie Y, Liang J, Chang X.   +10 more
europepmc   +1 more source

The ubiquitin-binding protein ANKRD13A mediates VCP-dependent mitochondrial outer membrane rupture during PINK1/Parkin-mediated mitophagy. [PDF]

J Biol Chem
Chu WH, Lin YS, Guo J, Jane WN, Wang WJ, Lin YY, Liu PH, Huang PY, Chiang WC.   +8 more
europepmc   +1 more source

Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes. [PDF]

FASEB J
Özel C, Reitmeier KM, Kieckhöfer E, Abualia K, Nguyen-Minh D, Matin M, Hagmann H, Coward RJM, Brähler S, Antczak P, Schermer B, Benzing T, Giavalisco P, Brinkkoetter PT.   +13 more
europepmc   +1 more source

Targeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells

Targeting BIG3–PHB2 interaction to overcome tamoxifen resistance in breast cancer cells
The acquisition of endocrine resistance is a common obstacle in endocrine therapy of patients with oestrogen receptor-α (ERα)-positive breast tumours. We previously demonstrated that the BIG3–PHB2 complex has a crucial role in the modulation of oestrogen/ERα signalling in breast cancer cells.
openaire  

Receptor-mediated mitophagy: a new target of neurodegenerative diseases. [PDF]

Front Neurol
Yang J, Yang F, Chen G, Liu M, Yuan S, Zhang TE.   +5 more
europepmc   +1 more source

SLP2/PHB Aggregates in ALS Mouse Models and Patients: Implications Beyond CHCHD10-Associated Motor Neuron Disease. [PDF]

Int J Mol Sci
Genin EC, Lespinasse F, Mauri-Crouzet A, Dupuis L, Paquis-Flucklinger V.   +4 more
europepmc   +1 more source

Focusing on the Apolipoprotein M-Mitophagy Axis: A Mechanism for Renal Protection in Diabetic Nephropathy. [PDF]

J Diabetes Res
Chen T, Yang M.
europepmc   +1 more source

IGFBP6 orchestrates antiinfective immune collapse in murine sepsis via prohibitin-2-mediated immunosuppression. [PDF]

J Clin Invest
Chen K, Hu Y, Yu X, Tang H, Ruan Y, Li Y, Gao X, Zhao Q, Wang H, Zhang X, Molloy DP, Yin Y, Chen D, Song Z.   +13 more
europepmc   +1 more source

Inhibiting CMTM4 reverses the immunosuppressive function of myeloid-derived suppressor cells and augments immunotherapy response in cervical cancer. [PDF]

J Immunother Cancer
Ding J, Hu H, Zhu Y, Xu X, Yin B, Yang M, Zhou H, Huang T, Li M, Kou Y, Rahim Z, Huang B, Li A, Wang W, Han L.   +14 more
europepmc   +1 more source