Results 241 to 250 of about 296,962 (311)

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Impact of High Hydrostatic Pressure and Soaking Solutions on the Surface Structure, Carotenoids, Individuals' Phenolic Acids and Flavonoids Profile of Orange-Fleshed Sweet Potato Flour. [PDF]

Food Sci Nutr
Azeem M, Nasir R, Amjad S, Hussain N, Islam K, Wadood SA, Mohamed Ahmed IA, Walayat N, Habinshuti I.   +8 more
europepmc   +1 more source

Lewis Pair‐Engineered CuMnOx as Cold‐Adapted Multinanozyme for Cooperative Hydrolytic and Oxidative Degradation of Raw Corn Stalk

Advanced Science, EarlyView.
A Lewis pair site design strategy was established to construct Cu‐doped Mn‐based amorphous nanozymes, where Mn and oxygen vacancies generate cooperative acid‐base pairs. The resulting multinanozyme integrates glycosidase‐, oxidase‐, and cold‐adapted enzyme‐mimicking activities, enabling cooperative depolymerization of cellulose and hemicellulose ...
Huile Liu, Ziyi Di, Qing Tian, Yue Zhou, Rong Yang, Zhiyi Bai, Haoyu Wang, Yao Chen, Lianbing Zhang   +8 more
wiley   +1 more source

Angiotensin-Converting Enzyme Inhibitory Activity of Selected Phenolic Acids, Flavonoids, Their <i>O</i>-Glucosides, and Low-Molecular-Weight Phenolic Metabolites in Relation to Their Oxidation Potentials. [PDF]

Metabolites
Zielińska D, Starowicz M, Wronkowska M, Zieliński H.   +3 more
europepmc   +1 more source

Self‐Sustaining Piezozyme Platform for Antifouling via Mechanically Triggered Enzymatic Cascade

Advanced Science, EarlyView.
Wave‐powered CeO2/g‐C3N4 piezozyme coating converts ocean motion into an enzymatic H2O2‐to‐ROS cascade, realizing 180‐day eco‐friendly marine antifouling. ABSTRACT Harnessing ubiquitous mechanical energy for catalytic activation offers an emerging pathway toward self‐sustaining environmental protection systems.
Jingyu Wang, Yanjun Yu, Rongxin Su, Jiangjiexing Wu   +3 more
wiley   +1 more source

The Impact of Lighting Treatments on the Biosynthesis of Phenolic Acids in Black Wheat Seedlings. [PDF]

Foods
Lan H, Wang C, Yang Z, Zhu J, Fang W, Yin Y.   +5 more
europepmc   +1 more source

Synergistic Enhancement of Catalytic Activities in Ligand‐Regulated Carbon Dots‐Ferric Ion Nanozymes via UV‐Enhanced Peroxidase‐Oxidase

Advanced Science, EarlyView.
Three CDs‐Fe nanozymes functionalized with tailor‐made ligands (TPP, HEDP, and DTPA) are synthesized via hydrothermal carbonization and coordination chemistry. A ligand‐regulation strategy for CDs‐Fe nanozymes achieves tunable enzyme‐mimicking activities and a powerful synergistic effect between POD and UV‐induced OXD pathways, paving the way for ...
Xiangli Li, Jiaxin Dong, Dechang Jia, Yu Zhou, Baoqiang Li   +4 more
wiley   +1 more source

Two Novel Hydrate Salts of Norfloxacin with Phenolic Acids and Their Physicochemical Properties. [PDF]

Antibiotics (Basel)
Liang D, Li F, Duan J, Sun W, Yu X.
europepmc   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Investigation of the quality, antimicrobial, and antioxidant effects of commercial carob molasses and determination of phenolic acids by using HPLC. [PDF]

J Food Sci
Orhan DD, Sulak EM, Pekacar S, Gok HN, Ozüpek B, Özçelik B.   +5 more
europepmc   +1 more source