Liquid Chromatography‒Tandem Mass Spectrometry Analysis of Primary Metabolites and Phenolic Acids Across Five Citrus Species. [PDF]
Peng Y +6 more
europepmc +1 more source
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng +8 more
wiley +1 more source
Assessment of in vitro skin permeation and accumulation of phenolic acids from honey and honey-based pharmaceutical formulations. [PDF]
Nowak A +9 more
europepmc +1 more source
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu +9 more
wiley +1 more source
Impact of High Hydrostatic Pressure and Soaking Solutions on the Surface Structure, Carotenoids, Individuals' Phenolic Acids and Flavonoids Profile of Orange-Fleshed Sweet Potato Flour. [PDF]
Azeem M +8 more
europepmc +1 more source
ABSTRACT Acute liver injury (ALI), driven by diverse insults such as drug toxicity and ischemia‐reperfusion, poses a high mortality risk and lacks targeted therapies. While reactive oxygen species (ROS), neutrophil extracellular traps (NETs), and a coordinated cell death pathway PANoptosis have been implicated, their interplay as a unified pathogenic ...
Xiaopeng Cai +13 more
wiley +1 more source
Application of response surface methodology for obtaining fermented extract of <i>Sanguisorba officinalis</i> L. herb with high antioxidant activity, polyphenols, and lactic acid content: analysis of the content and skin permeation of selected phenolic acids. [PDF]
Muzykiewicz-Szymańska A +4 more
europepmc +1 more source
Engineering an Optogenetic pH‐Modulator in Bacteria
ABSTRACT Cells in many naturally occurring organisms routinely cooperate to control their extracellular pH in a dynamic and reversible manner, but this capability has been underexplored in synthetic biology. Here, we sought to engineer a microbial system that switches between two states —high and low extracellular pH— with minimal human intervention ...
Jenevieve Kuang +7 more
wiley +1 more source
The Impact of Lighting Treatments on the Biosynthesis of Phenolic Acids in Black Wheat Seedlings. [PDF]
Lan H +5 more
europepmc +1 more source
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan +13 more
wiley +1 more source

