Results 71 to 80 of about 6,515,835 (350)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Effects of Organic Acids, Amino Acids and Phenolic Compounds on Antioxidant Characteristic of Zhenjiang Aromatic Vinegar

Molecules, 2019
Zhenjiang aromatic vinegar (ZAV) is one of the famous Chinese vinegars, which contains various physicochemical and bioactive compositions. In the present study, physicochemical properties and total antioxidant activity were detected in ZAV samples.
Bo Zhang, Ting Xia, Wenhui Duan, Zhujun Zhang, Yu Li, Bin Fang, Menglei Xia, Min Wang   +7 more
doaj   +1 more source

Profile of Phenolic Acids and Antioxidant Capacity in Organs of Common Buckwheat Sprout [PDF]

, 2016
The aim of the study was to analyse the content of phenolic acids, total phenolic compounds, proanthocyanidins, and antioxidant capacity in cotyledons and hypocotyl of five cultivars of common buckwheat (Fagopyrum esculentum Moench) sprout.
Horbowicz, M., Kasprzykowski, Z., Mitrus, J., Sawicki, T., Szawara-Nowak, D., Wiczkowski, W.   +5 more
core   +1 more source

Whole Grains and Phenolic Acids: A Review on Bioactivity, Functionality, Health Benefits and Bioavailability

Nutrients, 2018
Cereal grains represent one of the major sources of human food and nowadays, their production has increased to fulfill the needs of the world’s population.
L. Călinoiu, D. Vodnar
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Content of phenolic acids in rye caryopses determined using DAD-HPLC method

Czech Journal of Food Sciences, 2001
Phenolic compounds were extracted from rye caryopses with 80% (v/v) methanol. Phenolic acids were determined as free compounds and those liberated from soluble esters and glycosides.
R. Amarowicz, S. Weidner
doaj   +1 more source

Accumulation of Phenolic Acids during Storage over Differently Handled Fresh Carrots

Foods, 2020
Carrots contain a significant content of phenolic compounds, mainly phenolic acids. Technological processing of carrots inflicts wounding stress and induces accumulation of these compounds, especially caffeic acid derivatives, in the periderm tissue.
Jarkko Hellström, Daniel Granato, Pirjo H. Mattila   +2 more
doaj   +1 more source

Evaluation of Phenolic Root Exudates as Stimulants of Saptrophic Fungi in the Rhizosphere

Frontiers in Microbiology, 2021
The rhizosphere microbial community of crop plants in intensively managed arable soils is strongly dominated by bacteria, especially in the initial stages of plant development.
Anna Clocchiatti, Anna Clocchiatti, S. Emilia Hannula, Marlies van den Berg, Maria P. J. Hundscheid, Wietse de Boer, Wietse de Boer   +6 more
doaj   +1 more source

Factors affecting sorghum protein digestibility [PDF]

, 2003
In the semi-arid tropics worldwide, sorghum (Sorghum bicolor (L.) Moench) is cultivated by farmers on a subsistence level and consumed as food by humans.
Belton, Peter, Duodu, K, Hamaker, BR, Taylor, JRN   +3 more
core   +1 more source

Drought stress enhances nutritional and bioactive compounds, phenolic acids and antioxidant capacity of Amaranthus leafy vegetable

BMC Plant Biology, 2018
BackgroundBioactive compounds, vitamins, phenolic acids, flavonoids of A. tricolor are the sources of natural antioxidant that had a great importance for the food industry as these detoxify ROS in the human body.
Umakanta Sarker, S. Oba
semanticscholar   +1 more source