Results 61 to 70 of about 6,515,835 (350)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Comparative study of phenolic acids from underground parts of Rheum palmatum L., R. rhaponticum L. and R. undulatum L.

Acta Societatis Botanicorum Poloniae, 2011
In three species of Rheum L. genus growing in Poland the composition of phenolic acids was determined. By 2D-TLC method the following acids were identified: ellagic, chlorogenic, gallic, protocatechuic, homoprotocatechuic, caffeic, α-resorcilic, p ...
Helena Danuta Smolarz, Ewa Medyńska
doaj   +1 more source

Comparative evaluation of phytochemical profiles and identification of flavonoids in cereal grains [PDF]

, 2009
The phytochemicals including flavonoids and phenolic acids mainly contained in the outer layer of the kernels are key factors responsible for the biofunctionality of whole grains.
Borgen, Anders, Liu, Q, Trust, Beta
core  

Phenolic metabolites of anthocyanins following a dietary intervention study in post-menopausal women [PDF]

, 2014
Scope Numerous studies feeding anthocyanin-rich foods report limited bioavailability of the parent anthocyanins. The present study explores the identity and concentration of the phenolic metabolites of anthocyanins in humans.
Aura, Azzini, Berg, Bitsch, Cao, Cassidy, Cassidy, Curtis, Czank, Del Rio, Dykes, Edirisinghe, Egert, Felgines, Fossen, Garcia-Alonso, Gonzalez-Barrio, Griffiths, Hollman, Kay, Kay, Kay, Koli, Manach, Milbury, Mink, Mullen, Murkovic, Mülleder, Nurmi, Russell, Schmitzer, Selma, Toromanović, Valentova, Veberic, Vitaglione, Weber, Williamson, Williamson, Winter, Wu, Xu, Zhang, Zhang   +44 more
core   +1 more source

Soil acidification in continuously cropped tobacco alters bacterial community structure and diversity via the accumulation of phenolic acids

Scientific Reports, 2019
Studying the obstacles associated with continuous cropping is necessary for sustainable agricultural production. Phenolic acids play an important role in continuous cropping systems, although their mechanism of action in these systems remains unclear ...
Yu-xiang Bai, Ge Wang, Ya-Dong Cheng, Puyou Shi, Chengcui Yang, Huan-wen Yang, Zhaoli Xu   +6 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda incrassata (Chlorophyta, Bryopsidales) [PDF]

, 2017
Seaweeds are a source of natural antioxidants having potential application in oxidative stress and associated diseases. In this work, anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda ...
Claudina, Zaldívar-Munoz, Costa-Mugica, Ariadna, Dalva, Assuncao Portari de Mancini, de Oliveira e Silva, Ana, Mara, Diaz-Gutierrez, Daylín, Mancini-Filho, Jorge, Vazquez, Ana María, Vidal-Novoa, Alexis, Zulueta Díaz, Yenisleidy de Las Mercedes   +8 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Physiological mechanism of improved tolerance of Saccharomyces cerevisiae to lignin-derived phenolic acids in lignocellulosic ethanol fermentation by short-term adaptation

Biotechnology for Biofuels, 2019
Background Phenolic acids are lignin-derived fermentation inhibitors formed during many pretreatment processes of lignocellulosic biomass. In this study, vanillic, p-hydroxybenzoic, and syringic acids were selected as the model compounds of phenolic ...
Hanqi Gu, Yuyong Zhu, Yanfang Peng, Xiujun Liang, Xiaoguang Liu, Lingzhi Shao, Yanyan Xu, Zhaohe Xu, Ran Liu, Jie Li   +9 more
doaj   +1 more source

Recovery of Polyphenols from Brewer’s Spent Grains [PDF]

, 2019
peer-reviewedThe recovery of antioxidant polyphenols from light, dark and mix brewer’s spent grain (BSG) using conventional maceration, microwave and ultrasound assisted extraction was investigated.
Birsan, Rares, Rai, Dilip K., Waldron, Keith, Wilde, Peter   +3 more
core   +2 more sources