Results 121 to 130 of about 98,679 (202)
Heterozygous OGDH Variants Are Involved in Peripheral Neuropathy With Ataxia and Optical Atrophy
JIMD Reports, Volume 67, Issue 4, July 2026.ABSTRACT
2‐oxyglutarate dehydrogenase (OGDH) encodes an E1 component of α‐ketoglutarate dehydrogenase complex that plays a pivotal role in the Krebs cycle. Biallelic variants in OGDH have been reported to cause an early‐onset neurodevelopmental and mitochondrial disorder.Liedewei Van de Vondel, Gyu S. Lee, Jonathan De Winter, Satoshi Matsuzaki, Abigail Sandoval, Juan Felipe Ramirez, Alice Monticelli, Sukyeong Lee, Rita Horvath, Jan de Bleecker, Stephan Züchner, Kenneth M. Humphries, Jonathan Baets, Wan Hee Yoon +13 morewiley +1 more sourceA novel common variant in DCST2 is associated with length in early life and height in adulthood [PDF]
, 2014 Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide ...Freathy, R.M., A. G. Uitterlinden (7611476), Tiesler, C. M., H. Bisgaard (7626128), Gehring, U, Ang, W., Kreiner-Møller, Eskil, Liang, L, Eriksen, Patrick, Tiesler, Carla M.T., C. Medina-Gomez (7653182), Kerkhof, M., IRAS RATIA2, Niinikoski, Harri, Simpson, Angela; id_orcid, Gehring, U., Curtin, John A., D. M. Evans (7624460), V. Lindi (7653236), Dedoussis, George V, Buxton, JL, Kemp, John P, Blakemore, A.I., Barton, S.J., Barton, S., Teo, Y-Y, Raitakari, O. T., van Duijn, C. M., Uitterlinden, Andre G., A. Palotie (7632986), Mentch, F. D., Atalay, M., Hirschhorn, Joel, Dedoussis, G. V., Postma, Dirkje S., Ang, W, Lindi, V, Uitterlinden, André G, Evans, D., Lowe, W.L., Barton, SJ, T. H. Pers (7626953), Dedoussis, G., A. Bergström (5568635), Widen, E., Simpson, Angela, Joro, R., Hakonarson, Hakon, J. Ilonen (7653254), Koppelman, Gerard H, Jaddoe, Vincent W.V., Simpson, A, Jarvelin, M., Davey Smith, George, Pers, T. H., Huikari, V, Grant, SFA, Frayling, Timothy M., Taal, HR, Armstrong, Loren L., Cousminer, D. L., Uitterlinden, AG, Evans, DM, Timpson, Nicholas J, Hofman, A., Joro, Raimo, X. Estivill (7620254), van der Valk, R J, Stokholm, Jakob, Eriksson, Johan, Alves, ADC, Eriksen, P., Jaddoe, Vincent W. V., Gonzalez, J. R., Lewin, A, Boomsma, D. I., Dedoussis, GV, Hartikainen, Anna-Liisa, Jarvelin, Marjo-Riitta, Davey Smith, G., Taal, H., R. Joro (7653137), de Jongste, J., Sergeyev, E, Bustamante Pineda, Mariona, M. G. Hayes (7653119), Pennell, C.E., Smith, GD, Sunyer, J., van Duijn, CM, Rivadeneira, F, Palotie, A, Jacobsson, Bo, Chawes, B., J. N. Hirschhorn (7609139), Barton, Sheila J, Warrington, Nicole M., Jarvelin, M.R., Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Jaddoe, V., B. Chawes (7653164), Eriksson, J, W. Kiess (7653197), Sergeyev, E., Da Silva Couto Alves, A, Rodriguez, Alina,, van Duijn, C., Sebert, S., ?, ?, Lifecourse Epidemiology, Consortium, Ntalla, I., Dedoussis, George V., M. Groen-Blokhuis (7653251), Duijn, Cornelia, T. Lakka (7653233), C. E. Pennell (7653287), Pers, T., Hakonarson, H., Buxton, J., Alves, A.D.S.C., Hirschhorn, J. N., Thiering, E, van der Valk, Ralf J. P., Llop, S, Mccarthy, Mark I, A. Custovic (3516569), Kooijman, Marjolein N., Palotie, A., Holloway, J. W., M Guxens (7653107), Early, Genetics, B. Jacobsson (7653278), Tiesler, C., Jaddoe, V.W., Jacobsson, B., Chawes, Bo, Raitakari, Olli T., Myhre, R, N. J. Timpson (7608851), Horikoshi, M, Waage, J., Pers, TH, Ring, Susan M, Saw, SM, Warrington, Nicole M, van der Valk, Ralf J.P., Körner, Antje, A. Rodriguez (7653227), Sunyer, Jordi, Melbye, Mads, Stergiakouli, E, Alves, Alexessander Da Silva Couto, Freathy, Rachel M., Bergstrom, A., Holloway, J.W., Kiess, W, Huang, J, Jaddoe, VW, Tiesler, Carla M. T., Mentch, FD, Jaddoe, VWV, Bergström, A, A. Sevelsted (7653176), Hayes, M., Armstrong, LL, Kreiner-Moller, E, Grant, S. F., Jacobsson, Bo,, Hayes, M Geoffrey, Veijola, R, E. Thiering (7653128), Sevelsted, A., Pennell, Craig E, Cousminer, D.L., de Jongste, J.C., Hartikainen, A.-L., Hayes, MG, Lakka, Timo, Lowe, WL, J. A. Curtin (7653131), Ilonen, Jorma, Hayes, M. G., Feenstra, B, N. Pitkänen (7653143), Stokholm, J., A. Lewin (7653218), Newnham, J., Ilonen, J, E. Zeggini (7632767), R. J. P. van der Valk (7653101), Holloway, JW, van Duijn, C.M., St Pourcain, B, Gonzalez, Juan R., Tiesler, CM, Alves, ADSC, C. M. T. Tiesler (7653200), Eriksen, P, LS IRAS EEPI ME (Milieu epidemiologie), Ring, S.M., Curtin, John A, Armstrong, L.L., Lowe, W., Freathy, Rachel M, Franke, L, Koerner, A, R. M. Freathy (7653149), Ntalla, I, Murray, C.S., A. Da Silva Couto Alves (7653221), J. P. Bradfield (7646234), Jaddoe, Vincent WV, H. R. Taal (7653185), Kemp, J.P., Huikari, Ville, Pitkanen, Niina, Feenstra, Bjarke, Niinikoski, H., Kreiner-Møller, E, Keinanen-Kiukaanniemi, S, N. M. Warrington (7624496), Uitterlinden, A. G., V. Huikari (7644278), Lewin, Alexandra, J. L. Buxton (7653224), Atalay, M, Mentch, F.D., Armstrong, L., Tiesler, CMT, Bisgaard, H., Kerkhof, M, Kerkhof, Marjan, Buxton, J. L., Guxens, Monica, Tiesler, C.M., Teo, Yik-Ying, Bønnelykke, K., J. Waage (7653170), Ioanna Ntalla (174685), Holloway, J., Bradfield, J. P., Frayling, TM, Huang, J., Liang, Liang, H. Niinikoski (7653290), Warrington, N. M., McCarthy, M.I., Holloway, John W., E. Kreiner-Møller (7626173), Widén, E, Thiering, Elisabeth, Kooijman, M.N., Hocher, Berthold (Prof.), Murray, C. S., Jarvelin, MR, Uitterlinden, A., Knip, M., van Duijn, Cornelia M., Estivill, Xavier, Pers, Tune H., de Jongste, JC, Sevelsted, Astrid, Jarvelin, M.-R., Kooijman, M. N., W. Ang (7653239), Waage, Johannes, Postma, D. S., Stokholm, J, Curtin, J.A., Hakonarson, H, Koppelman, Gerard H., Bonnelykke, K., Saaf, Annika, S. M. Ring (7632752), J. Stokholm (7653167), Teo, Y. Y., B. Feenstra (7653266), Grant, S.F., Barton, Sheila J., C. S. Murray (7653203), M-R. Jarvelin (7653281), Kull, I, F. D. Mentch (7653161), S. Llop (7653194), Kemp, J., Evans, David M, L. L. Armstrong (7653188), Melbye, M, Bønnelykke, K, Barton, S. J., Curtin, JA, Timpson, Nicholas J., Kemp, John P., Hofman, Albert, Raitakari, O.T., Sääf, A, Pahkala, Katja, Jaddoe, V. W., Blakemore, Alexandra I, Hartikainen, A. L., Joro, R, Hirschhorn, Joel N, Custovic, A., Pahkala, K., Rodriguez, Alina, Evans, David M., W. L. Lowe (7653269), Lindi, V., M. N. Kooijman (7653104), Cousminer, Diana L, Kemp, JP, Ntalla, Ioanna, E. Sergeyev (7653275), Tiesler, Carla MT, Mccarthy, M., R. Myhre (7653134), Kull, Inger, González Ruiz, Juan Ramón, Koppelman, Gerard H.; id_orcid, J. Eriksson (7653191), Myhre, R., van der Valk, Ralf J P, Lyytikainen, Leo-Pekka, M. Horikoshi (7647380), Armstrong, Loren L, Y-Y. Teo (7653152), Mccarthy, MI, Genetic Investigation of, ANthropometric Traits Consortium, Geller, F., Curtin, J., Murray, Clare S; id_orcid, Melbye, M., Warrington, NM, Buxton, Jessica L, R. Veijola (7653146), Newnham, JP, A. Sääf (7653113), Pennell, C. E., Lyytikainen, L.-P., M. I. Mccarthy (7653296), Evans, D.M., Kooijman, M., Medina-Gomez, C, Chawes, Bo Lund Krogsgaard, Knip, M, Bonnelykke, K, Kooijman, Marjolein N, Cousminer, Diana L., Kiess, W., Lowe, William L., Hartikainen, A.L., Llop, S., Pitkanen, N., G. V. Dedoussis (7653293), Tiesler, Carla M T, Warrington, N., Freathy, R., Kooijman, Marjolein, Taal, H.R., Veijola, R., Kooijman, MN, Lakka, T, TEO, Y.-Y., Guxens Junyent, Mònica, Liang, L., Kaakinen, M, Taal, H. R., Groen-Blokhuis, Maria, Chawes, B, Horikoshi, M., Körner, A, B. St Pourcain (7653158), Sebert, S, Kaakinen, Marika, Freathy, RM, Raitakari, Olli T, Curtin, J. A., Groen-Blokhuis, M, F. Rivadeneira (7611509), Genetic Invest ANthropometric, Kreiner-Moller, Eskil, Gonzalez, J.R., Niinikoski, H, S. Keinanen-Kiukaanniemi (7653215), Hofman, Bert, J. P. Kemp (7624478), Da Silva Couto Alves, A., C. M. van Duijn (7626872), U. Gehring (7626152), Koppelman, G. H., D. S. Postma (3809164), K. Bønnelykke (7653299), Jongste, Johan, Murray, Clare S, Hartikainen, A., Lyytikainen, L-P, Saaf, A., Gonzalez, Juan R, Grallert, H., van der Valk, R. J., Palotie, Aarno, Pers, T.H., Zeggini, E, Sergeyev, Elena, Teo, Y., Korner, A., Hartikainen, AL, I. Kull (3516731), Early Genetics Lifecourse, M. Knip (7653260), Early Growth Genetics, Consortium, Uitterlinden, André, Gonzalez, JR, H. Grallert (4107469), Lindi, Virpi, Teo, YY, G. H. Koppelman (3809212), Bustamante, Mariona, S. J. Barton (7653155), St Pourcain, Beate, Smith, G.D., Grant, S.F.A., Frayling, T., McCarthy, M. I., Stergiakouli, E., Newnham, John P., Zeggini, Eleftheria, Hocher, Berthold, Murray, C., Saw, S. M., Eriksson, J., Ang, Wei, A. I. Blakemore (7652759), Hayes, M.G., S. F. A. Grant (7653263), Sunyer, J, Grant, Struan F A, Lyytikäinen, LP, Mccarthy, Mark I., Rivadeneira, Fernando, Huang, Jinyan, Magnus, P, Sengpiel, Verena,, Buxton, Jessica L., Grallert, Harald, Risk Assessment, Jarvelin, M-R, Groen-Blokhuis, M.M., Knip, Mikael, Raitakari, O., Blakemore, AI, Bisgaard, Hans, L. Liang (6079640), Guxens, M, Da Silva Couto Alves, Alexessander, V. W. V. Jaddoe (7653302), Teo, Y.Y., Gonzalez, J., Warrington, N.M., Simpson, A., Widen, Elisabeth, Raitakari, OT, Bisgaard, H, Franke, Lude, Lakka, T., Koerner, Antje, Rodriguez, A, Pennell, Craig E., de Jongste, J. C., de Jongste, Johan C., Tiesler, C.M.T., Grant, Struan F.A., Blakemore, A., M. Vaarasmaki (7653230), Lewin, A., P. Magnus (3570941), Bustamante, M., Jarvelin, M. R., Davey Smith, G, E. Stergiakouli (7653110), Veijola, Riitta, Murray, Clare S., de Jongste, Johan C, Cousminer, DL, Mahajan, A, Dedoussis, G.V., A. Simpson (7653206), E. Widén (7653272), van der Valk, R.J.P., Jaddoe, Vincent W V, Grant, Struan F. A., D. L. Cousminer (7653122), Atalay, Mustafa, Flexeder, Claudia, Blakemore, A. I., Frayling, Timothy M, Boomsma, D.I.; id_orcid, C. Flexeder (7626146), Estivill, Xavier, 1955-, Timpson, N. J., A-L. Hartikainen (7653212), Bradfield, J.P., Ring, S., Hayes, M. Geoffrey, Timpson, NJ, F. Geller (7653116), Boomsma, Dorret I, Grant, S., Buxton, J.L., St Pourcain, B., Cousminer, D., Pennell, CE, M. Bustamante (2906126), Boomsma, D., Holloway, John W, Bradfield, JP, van der Valk, RJP, H. Hakonarson (7609127), Hocher, B, Armstrong, L. L., Uitterlinden, André; id_orcid, Mentch, F., Postma, Dirkje S, Keinanen-Kiukaanniemi, Sirkka, Early Growth Genetics (EGG) Consortium, Ring, SM, Rivadeneira, F., Bradfield, Jonathan P, K. Panoutsopoulou (7632989), Feenstra, B., M. Kerkhof (7653140), Genetic Investigation of ANthropometric Traits (GIANT) Consortiu, Sengpiel, V., Smith, George Davey, Postma, D.S., Mentch, Frank D., Sunyer Deu, Jordi, Boomsma, Dorret I., Hirschhorn, J.N., Medina-Gomez, Carolina, E. Melén (3494549), M. Atalay (7653284), Saw, S., van der Valk, R., Vaarasmaki, M., Medina-Gomez, C., Blakemore, Alexandra I., Hocher, B., L-P. Lyytikäinen (7653245), Sengpiel, V, Evans, D. M., Waage, J, van der Valk, R.J., Kaakinen, M., Flexeder, C, Panoutsopoulou, K, Geller, F, Saw, S.-M., Murray, CS, Sengpiel, Verena, Early Growth Genetics EGG, Koppelman, G., Guxens, M., Jacobsson, B, van der Valk, RJ, Rodriguez, A., Lyytikainen, L. P., Valk, Ralf, Taal, Rob; id_orcid, Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, Llop, Sabrina, Sebert, Sylvain, D. I. Boomsma (1812745), Kiess, Wieland, Koppelman, GH, Timpson, N., Boomsma, DI, Grant, SF, Pers, Tune H, Custovic, Adnan, Pennell, C., Grant, Struan FA, Mahajan, A., Newnham, John P, Jaddoe, Vincent, Ring, S. M., Uitterlinden, A.G., Saw, Seang-Mei, Blakemore, Alexandra I. F., Pers, Tune Hannes, Ilonen, J., Koppelman, G.H., Kull, I., S. Sebert (7626812), Estivill, X., Franke, L., Estivill, X, Hirschhorn, J., Jaddoe, V.W.V., Sevelsted, A, Myhre, Ronny, Koerner, A., Lowe, William L, Stergiakouli, Evangelia, A. Körner (7653125), Gehring, Ulrike, Bonnelykke, Klaus, Geller, Frank, Hartikainen, A-L, Zeggini, E., van der Valk, Ralf JP, J. Sunyer (3516257), Mentch, Frank D, Hirschhorn, Joel N., Taal, H Rob, Vaarasmaki, M, Melen, Erik, Seang-Mei Saw (159451), Liang, Liming, Thiering, E., J. Huang (2342368), L. Franke (7602401), Boomsma, D.I., T. M. Frayling (7608959), Hofman, A, Bradfield, Jonathan P., A. Hofman (4269889), P. Eriksen (7653173), Bustamante, M, Postma, D., J. W. Holloway (7611494), Kerkhof, Marjon, Melén, E, J. C. de Jongste (7626116), Frayling, T.M., Panoutsopoulou, K., M. Melbye (7653179), Taal, H. Rob, Huikari, V., Grallert, H, K. Pahkala (7653248), Ring, Susan M., J. P. Newnham (7653242), Pitkänen, N, Lyytikainen, L., Bradfield, J., Custovic, A, Bønnelykke, Klaus, Magnus, P., Vaarasmaki, Marja, Groen-Blokhuis, M., Postma, DS, Melen, E., Lowe, W. L., Newnham, J. P., Keinanen-Kiukaanniemi, S., B. Hocher (7653257), Kreiner-Moller, E., Newnham, J.P., J. R. Gonzalez (7606541), A. Mahajan (7603748), Kemp, J. P., Hirschhorn, JN, M. Kaakinen (7626740), Kreiner-Møller, E., van Duijn, Cornelia M, G. D. Smith (4912390), Bergstrom, Anna, Magnus, Per, Pahkala, K, Panoutsopoulou, Kalliope, V. Sengpiel (7653209), Flexeder, C., Taal, Rob, Timpson, N.J., Mahajan, Anubha, O. T. Raitakari (7647452), Saw, S-M, Horikoshi, Momoko, Saw, S.M. +679 morecore +1 more sourceStructural, Compositional, and Dielectric State Profiling in Label‐Free Single‐Cell Monitoring
Small Methods, Volume 10, Issue 13, 8 July 2026.Label‐free single‐cell monitoring leverages distinct physical interactions to access structural, compositional, and dielectric states of cells, enabling non‐perturbative, repeatable, and information‐rich measurements across diverse biological contexts. This review organizes representative platforms by intrinsic state variables and connects measurement ...Changi Baek, Youngho Song, Seongcheol Park, Sujin Hyung, Sang Eun Yoon, Yong Jae Shin, Soo‐Yeon Cho +6 morewiley +1 more sourceEvaluation of association of HNF1B variants with diverse cancers : collaborative analysis of data from 19 genome-wide association studies [PDF]
, 2010 Background
Genome-wide association studies have found type 2 diabetes-associated variants in the HNF1B gene to exhibit reciprocal associations with prostate cancer risk.Tomlinson, IP, Mann, GJ, Hwang, Shih-Jen, Hopper, John L., Hwang, SJ, Amos, CI, Barkardottir, Rosa B., McCarthy, Mark I, Carvajal-Carmona Luis, Albanes, D, Xu, J, Armstrong, Bruce K., Kenneth Muir, Stefansson Kari, Jacobs, EJ, Amos Christopher I., Zanke, B, Barkardottir, Rosa B, Jenab, M, Michaud, DS, Xu Jianfeng, Mendelsohn, JB, Muir, K, Hamdy, Freddie C., Stolzenberg-Solomon, RZ, Aitken, JF, Mathieu Lemire, Aitken, Joanne F., John P. A. Ioannidis, null null, Hunter, David, Hallmans, G, Donovan, Jenny L, Murabito Joanne M., Risch, HA, Hamdy, FC, Rafnar Thorunn, Giles, Graham G., Donovan, JL, Tomlinson, Ian P. M., Hunter David J., Margaret R Spitz, Macgregor, Stuart, Tomlinson Ian P. M., Spitz, Margaret R., Hopper, JL, David E. Neal, Duell, EJ, Stefansson, K, Simon N Stacey, Gudbjartsson, Daniel F, Julius Gudmundsson, David J Hunter, Armstrong, BK, Neal David E., Easton Douglas F., Amundadottir, L, Kari Stefansson, Stephen J Chanock, Hayward Nicholas K., Zeggini, E, Neal, David E, Isaacs, William B, Easton, DF, Chanock, Stephen J, Patel, AV, Douglas F. Easton, Brown Kevin M., Petersen, GM, Thorlacius, Steinunn, Isaacs, William B., William B Isaacs, Gallinger, S, Klein, AP, Gaborieau Valerie, Donovan, Jenny, Kraft, P, Kevin M Brown, Giovannucci, EL, Holly, EA, Lemire, Mathieu, Rosa B. Barkardottir, Sulem, P, Barkardottir, RB, Neal, David E., Zeggini, Eleftheria, Valerie Gaborieau, Chanock, Stephen J., Kevin M. Brown, Zeggini Eleftheria, Barkardottir, Rosa, HASH(0x55a67fc6f008), Riboli, E, Hayward, NK, Shu, XO, Howard, B, David E Neal, Stacey, Simon N., Gronberg, H, PanScan, C, Parikh, H, Gudmundsson Julius, Hassan, M, Ian P. M. Tomlinson, Tomlinson, IPM, Ioannidis, JPA, Gudmundsson, Julius, Carvajal-Carmona, Luis, McCarthy, MI, Kefford, Richard F., Clipp, S, McCarthy Mark I., Donovan Jenny L., Brent Zanke, Muir, Kenneth, Neal, DE, Ioannidis, John P., Li, D, Amundadottir Laufey, Canzian, F, Eeles, RA, Rodriguez, L, Gudmundsson, J, Mark I. McCarthy, Xu, Jianfeng, Elliott, Katherine S, Hutchinson, A, Krogh, V, Mann, Graham J., Thomas, G, Ioannidis, John PA, Eeles Rosalind A., Brown, Kevin M., Stacey, SN, Ioannidis, John, Kefford, RF, Sulem, Patrick, Katherine S Elliott, Gudbjartsson Daniel F., Murabito, JM, Stacey Simon N., McCarthy, Mark I., Gudbjartsson, DF, Hamdy Freddie C., Jenny L. Donovan, Eleftheria Zeggini, Hunter, David J., Luis Carvajal-Carmona, Chanock, Stephen, Hayward, Nicholas K., Michael Gaziano, J, Hunter, David J, Shih-Jen Hwang, Jianfeng Xu, The PanScan Consortium, Buring, JE, Amos, Christopher I, Henrik Grönberg, PanScan Consortium, Giles, GG, Rafnar, Thorunn, Easton, Douglas F, Nicholas K. Hayward, Brown, KM, Chanock Stephen J., Jenny L Donovan, Rosalind A Eeles, Arslan, AA, Seminara, D, Goggins, M, Stefansson, Kari, Murabito, Joanne M., Hunter, DJ, McCarthy, Mark, Tomlinson, Ian PM, Donovan, Jenny L., Rajkovic, A, Zanke Brent, Hamdy, Freddie C, Nicholas K Hayward, Thorlacius Steinunn, Hayward, Nicholas K, Joanne M. Murabito, Lynch, SM, Isaacs William B., Daniel F. Gudbjartsson, Elliott, Katherine S., Ioannidis, John P. A., Fuchs, CS, de Andrade, M, Hankinson, SE, Grönberg Henrik, Lemire Mathieu, Christopher I. Amos, Gross, M, Mandelson, MT, Spitz, Margaret R, Ioannidis, John P.A., Helzlsouer, K, Laufey Amundadottir, Bracci, PM, Tomlinson, Ian, Kooperberg, C, Kurtz, RC, Grönberg, H, John P A Ioannidis, Sulem Patrick, Eeles, Rosalind A, McWilliams, RR, Gaborieau, V, Elliott Katherine S., Ioannidis, JP, Christopher I Amos, Tjønneland, A, Stuart Macgregor, Rosalind A. Eeles, Berg, CD, Rosa B Barkardottir, Joanne M Murabito, Isaacs, WB, Elliott, KS, Bamlet, WR, Freddie C. Hamdy, Macgregor, S, Freddie C Hamdy, Grönberg, Henrik, Carvajal-Carmona, L, Gaborieau, Valerie, Easton, Douglas F., Lemire, M, Rafnar, T, Simon N. Stacey, Olson, SH, Amundadottir, Laufey, Chanock, SJ, Cotterchio, M, Muir Kenneth, Stephen J. Chanock, Australian Melanoma Family Study Investigators, Ioannidis John P. A., Margaret R. Spitz, Thorlacius, S, Stacey, Simon N, Tomlinson, Ian P M, Spitz Margaret R., Ioannidis, John P A, Brennan Paul, Steinunn Thorlacius, Mark I McCarthy, Lacroix, A, Paul Brennan, David J. Hunter, Patrick Sulem, William B. Isaacs, Brennan, P, Hwang Shih-Jen, Brown, Kevin M, Douglas F Easton, Daniel F Gudbjartsson, Zheng, W, Katherine S. Elliott, Gudbjartsson, Daniel Fannar, Thorunn Rafnar, Bas Bueno-De-Mesquita, H, Hamdy, Freddie, Boutron-Ruault, MC, Gudbjartsson, Daniel F., Tomlinson, Ian P.M., Zanke, Brent, Macgregor Stuart, Barkardottir Rosa B., Amos, Christopher I., Murabito, Joanne M, Jacobs, KB, Australian, MFSI, Brennan, Paul, Peeters, PHM, Spitz, MR, Kaaks, R, Eeles, Rosalind A., Ian P M Tomlinson +280 morecore +1 more sourceExploring Effects of Age at the Onset of Myopia on Multiple Diseases Using Electronic Health Records
Ophthalmology SciencePurpose: To examine whether genetic predisposition to age at the onset of myopia is associated with the development of future diseases. Design: Mendelian randomization phenome-wide association study (MR-PheWAS) from the UK Biobank.Xiayin Zhang, PhD, Shan Wang, MD, Yu Huang, PhD, Yanjie Xie, PhD, Ishith Seth, MD, Gabriella Bulloch, MD, Chunran Lai, MD, Yijun Hu, PhD, Xianwen Shang, PhD, Mingguang He, PhD, Zhuoting Zhu, PhD, Honghua Yu, PhD +11 moredoaj +1 more sourceSAIGE-GPU: accelerating genome- and phenome-wide association studies using GPUs
BioinformaticsAbstract Motivation Genome-wide association studies (GWAS) at biobank scale are computationally intensive, especially for admixed populations requiring robust statistical models. SAIGE is a widely used method for generalized linear mixed-model GWAS but is limited by its CPU-based implementation,Alex Rodriguez, Youngdae Kim, Tarak Nath Nandi, Karl Keat, Rachit Kumar, Mitchell Conery, Rohan Bhukar, Molei Liu, John Hessington, Ketan Maheshwari, Sumitra Muralidhar, Jennifer Moser, Jennifer E Deen, Philip S Tsao, Sumitra Muralidhar, J Michael Gaziano, Elizabeth Hauser, Amy Kilbourne, Michael Matheny, Dave Oslin, J Michael Gaziano, Jessica V Brewer, Mary T Brophy, Kelly Cho, Lori Churby, Scott L DuVall, Saiju Pyarajan, Luis E Selva, Shahpoor (Alex) Shayan, Stacey B Whitbourne, J Michael Gaziano, Brady Stephens, Todd Connor, Themistocles L Assimes, Adriana Hung, Henry Kranzler, Samuel Aguayo, Sunil Ahuja, Kathrina Alexander, Xiao M Androulakis, Prakash Balasubramanian, Zuhair Ballas, Elizabeth S Bast, Jean Beckham, Sujata Bhushan, Edward Boyko, David Cohen, Louis Dellitalia, Gerald Wayne Dryden, L Christine Faulk, Joseph Fayad, Daryl Fujii, Saib Gappy, Frank Gesek, Michael Godschalk, Jennifer Greco, Todd W Gress, Samir Gupta, Salvador Gutierrez, Mark Hamner, John Harley, Daniel J Hogan, Adriana Hung, Robin Hurley, Pran Iruvanti, Frank Jacono, Darshana Jhala, Seema Joshi, Scott Kinlay, Michael Landry, Peter Liang, Suthat Liangpunsakul, Jack Lichy, Tze Shien Lo, C Scott Mahan, Ronnie Marrache, Stephen Mastorides, Kristin Mattocks, Paul Meyer, Jonathan Moorman, Providencia Morales, Timothy Morgan, Maureen Murdoch, Eknath Naik, James Norton, Olaoluwa Okusaga, Michael K Ong, Kris Ann Oursler, Ismene Petrakis, Samuel Poon, Amneet S Rai, Michael Rauchman, Richard Servatius, Satish Sharma, River Smith, Peruvemba Sriram, Patrick Strollo, Neeraj Tandon, Philip Tsao, Gerardo Villareal, Jessica Walsh, John Wells, Jeffrey Whittle, Mary Whooley, Peter Wilson, Junzhe Xu, Shing Shing Yeh, Andrew W Yen, Edmon Begoli, Georgia Tourassi, Sumitra Muralidhar, Pradeep Natarajan, Benjamin F Voight, Kelly Cho, John Michael Gaziano, Scott M Damrauer, Katherine P Liao, Wei Zhou, Jennifer E Huffman, Anurag Verma, Ravi K Madduri +120 moreopenaire +2 more sources
