Results 41 to 50 of about 2,749 (174)
Melanoma, Melanin, and Melanogenesis: The Yin and Yang Relationship
Frontiers in Oncology, 2022 Melanin pigment plays a critical role in the protection against the harmful effects of ultraviolet radiation and other environmental stressors. It is produced by the enzymatic transformation of L-tyrosine to dopaquinone and subsequent chemical and ...
Radomir M. Slominski +6 more
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Preliminary study on MC1R polymorphism in some cattle breeds raised in Italy
Italian Journal of Animal Science, 2011 Most of the Western European cattle breeds consist of standardised breeds with a definite coat colour (Renieri et al., 1984). Thus coat colour could be useful to detect genetic markers for cattle breed identification.
C. Renieri +5 more
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Sequence characterization and polymorphism of melanocortin 1 receptor gene in some goat breeds with different coat color of Mongolia [PDF]
Asian-Australasian Journal of Animal Sciences, 2019 Objective Extension and Agouti loci play a key role for proportions of eumelanin and pheomelanin in determining coat color in several species, including goat. Mongolian goats exhibit diverse types of coat color phenotypes. In this study, investigation of
Onolragchaa Ganbold +6 more
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Frontiers in Genetics, 2022 Nguni cattle are a Sanga type breed with mixed B. taurus and B. indicus ancestry and proven resistance to ticks, diseases and other harsh conditions of the African geographical landscape.
Langelihle Mbali Kunene +6 more
doaj +1 more source
Pigment Cell & Melanoma Research, 2018 AbstractAlthough melanin is a photoprotective pigment, its elevated photochemical reactivity could lead to various phototoxic processes. Photoreactivity of synthetic pheomelanin, derived from 5‐S‐cysteinyldopa (5SCD‐M) and its photodegradation products obtained by subjecting the melanin to aerobic irradiation with UV‐visible light, was examined ...
Andrzej Zadlo +9 more
openaire +3 more sources
Quantitative Analysis of Eumelanin and Pheomelanin in Hair and Melanomas
Journal of Investigative Dermatology, 1983 In this study, a method is provided for analyzing quantitatively the content and the class of melanin pigments in the tissues, e.g., hair and melanoma. The method is simple and rapid because it does not require the isolation of melanins from the tissues. The rationale was that permanganate oxidation of eumelanin yields pyrrole-2,3,5-tricarboxylic acid (
Ito, Shosuke, Jimbow, Kowichi
openaire +2 more sources
Label-Free Delineation of Human Uveal Melanoma Infiltration With Pump–Probe Microscopy
Frontiers in Oncology, 2022 Uveal melanoma (UM) is the most frequent primary intraocular malignancy in adults, characterized by melanin depositions in melanocytes located in the uveal tract in the eyes.
Bohan Zhang +9 more
doaj +1 more source
Journal of the Chinese Chemical Society, EarlyView.Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley +1 more source
Thin Amelanotic and Hypomelanotic Melanoma: Clinicopathological and Dermoscopic Features
MedicinaBackground and Objectives: Amelanotic/hypomelanotic melanomas (AHMs) account for 2–8% of all cutaneous melanomas. Due to their clinical appearance and the lack of specific dermoscopic indicators, AHMs are challenging to diagnose, particularly in thinner ...
Giovanni Paolino +11 more
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JEADV Clinical Practice, EarlyView.ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni +3 more
wiley +1 more source