Results 61 to 70 of about 5,719 (219)

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Towards Structure-Property-Function Relationships for Eumelanin

, 2005
We discuss recent progress towards the establishment of important structure-property-function relationships in eumelanins - key functional bio-macromolecular systems responsible for photo-protection and immune response in humans, and implicated in the ...
Ben J. Powell, Bolivar-Marinez, Boulton, Burkhart, Clancy, Crippa, da Silva, Damjanovic, Evan G. Moore, Forest, Gallas, Galvao, Hanyz, Il'ichev, Jastrzebska, Jennifer Riesz, Jung, Kipp, Kozikowski, Lakowicz, Longuet-Higgins, Mark R. Pederson, McGinnes, Meredith, Meredith, Nighswander-Rempel, Nighswander-Rempel, Nofsinger, Nofsinger, Paul Meredith, Pederson, Powell, Powell, Pullman, Richmond, Rosei, Sarna, Stark, Stark, Stark, Stephen P. Nighswander-Rempel, Teuchner, Tran, Wolbarsht, Zajac, Zhang, Zucca   +46 more
core   +1 more source

Cutaneous Malignant Melanoma Incidences Analyzed Worldwide by Sex, Age, and Skin Type over Personal Ultraviolet-B Dose Shows No Role for Sunburn but Implies One for Vitamin D\u3csub\u3e3\u3c/sub\u3e [PDF]

, 2016
Because the incidence of cutaneous malignant melanoma (CMM) was reported to increase with increasing terrestrial UVR (290–400 nm) doses in the US back in 1975 and a recent publication showed no association exists with UVR exposure at all, we set out to ...
Godar, Dianne E., Merrill, Stephen, Subramanian, Madhan   +2 more
core   +2 more sources

Genetic and phenotypic variation in wood tiger moths from the Caucasus: insights into male warning color variation

Insect Science, EarlyView.
Coloration serves several fitness‐related functions, including thermoregulation, immunity, social signaling, sexual selection, and predator avoidance. Consequently, color polymorphism can have a significant impact on a species’ interactions with its environment, including its relationships with predators, prey, and potential mates. The wood tiger moth (
Juan A. Galarza, Ossi Nokelainen, Melanie N. Brien, Cristina Ottocento, Bibiana Rojas, Janne K. Valkonen, Tamar Chunashvili, Tõnis Tasane, Chris D. Jiggins, Johanna Mappes   +9 more
wiley   +1 more source

Quantitation of eumelanin and pheomelanin markers in diverse biological samples by HPLC-UV-MS following solid-phase extraction.

PLoS ONE, 2019
Eumelanin and pheomelanin are well known and common pigments found in nature. However, their complex polymer structure and high thermostability complicate their direct chemical identification.
Susanne Affenzeller, Holm Frauendorf, Tobias Licha, Daniel J Jackson, Klaus Wolkenstein   +4 more
doaj   +1 more source

Hair coloration by gene regulation: fact or fiction? [PDF]

, 2015
The unravelling of hair pigmentation genetics and robust delivery systems to the hair follicle (HF) will allow the development of a new class of colouring products.
Branicki, Fang, Guenther, Hardman, Kondo, Liu, Lu, Parra, Peters, Seiberg, Tobin, Vogt   +11 more
core   +1 more source

Setmelanotide in Bardet‐Biedl Syndrome: A Case Report

Pediatric Dermatology, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith, Eric Sanfilippo, Lara Wine Lee   +2 more
wiley   +1 more source

Evidence of Unprecedented High Electronic Conductivity in Mammalian Pigment Based Eumelanin Thin Films After Thermal Annealing in Vacuum

Frontiers in Chemistry, 2019
Melanin denotes a variety of mammalian pigments, including the dark electrically conductive eumelanin and the reddish, sulfur-containing, pheomelanin.
Ludovico Migliaccio, Paola Manini, Davide Altamura, Cinzia Giannini, Paolo Tassini, Maria Grazia Maglione, Carla Minarini, Alessandro Pezzella   +7 more
doaj   +1 more source

Could eumelanin molecule from Streptomyces parvus BSB49 strain be a potential anticancer agent for lung cancer?

Medicine Science, 2023
Melanins, which are divided into five different subgroups as eumelanin, pheomelanin, allomelanin, neuromelanin and pyomelanin, are a heterogeneous and amorphous biopolymer family.
Hamit Emre Kizil, Sinan Bayram, Serdar Ozturk, Umit Karakas   +3 more
doaj   +1 more source

Influence of MC1R Gene Variants on Coat Color of Indicine Cattle Breeds

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Indicine cattle display a broad range of coat colors, representing a relevant and breed‐defining trait required for registration in breeder association. Among the genes involved in pigmentation, MC1R stands out for modulating the synthesis of melanin‐related proteins and remains poorly explored in indicine cattle breeds. Therefore, we aimed to
Silel V. S. A. Maciel, Ingrid P. P. Oliveira, Beatriz B. Senes, Carolaine J. S. Santana, Jackeline S. Alves, Edilane A. da Silva, Fernando O. Franco, Bárbara C. F. da Silva, Fernando C. Cairo, Frederico C. Cairo, Aníbal E. Vercesi‐Filho, Raphael B. Costa, Gregório M. F. de Camargo   +12 more
wiley   +1 more source