Results 41 to 50 of about 6,310 (247)
PheWAS associations for COVID-19 susceptibility in GP data.
, 2021 PheWAS associations for COVID-19 susceptibility in GP data.
Hanan Musa (11383838) +5 more
core +1 more source
EBioMedicine, 2020 Background: The three main alleles of the APOE gene (ε4, ε3 and ε2) carry differential risks for conditions including Alzheimer's disease (AD) and cardiovascular disease.
Amanda L. Lumsden +3 more
doaj +1 more source
Health effects of milk consumption: phenome-wide Mendelian randomization study
BMC Medicine, 2022 Background We performed phenome-wide Mendelian randomization analysis (MR-PheWAS), two-sample MR analysis, and systemic review to comprehensively explore the health effects of milk consumption in the European population.
Shuai Yuan +9 more
doaj +1 more source
Forest plot of PheWAS analyses of severe COVID-19 risk.
, 2021 Forest plot of PheWAS analyses of severe COVID-19 risk.
Hanan Musa (11383838) +5 more
core +1 more source
Large-Scale Simultaneous Testing of Cross-Covariance Matrices with Applications to PheWAS [PDF]
Statistica Sinica, 2019 Motivated by applications in phenome-wide association studies (PheWAS), we consider in this paper simultaneous testing of columns of high-dimensional cross-covariance matrices and develop a multiple testing procedure with theoretical guarantees. It is shown that the proposed testing procedure maintains a desired false discovery rate (FDR) and false ...
Cai, Tianxi +3 more
openaire +3 more sources
A simulation study investigating power estimates in phenome-wide association studies
BMC Bioinformatics, 2018 Background Phenome-wide association studies (PheWAS) are a high-throughput approach to evaluate comprehensive associations between genetic variants and a wide range of phenotypic measures.
Anurag Verma +6 more
doaj +1 more source
medRxiv, 2022 Summary: Deep-PheWAS is a platform for phenome wide association studies that creates clinically-curated composite phenotypes, and integrates quantitative phenotypes from primary care data, longitudinal trajectories of quantitative measures, disease ...
R. Packer +13 more
semanticscholar +1 more source
Forest plot of Phewas analyses of general COVID-19 susceptibility.
, 2021 Forest plot of Phewas analyses of general COVID-19 susceptibility.
Hanan Musa (11383838) +5 more
core +1 more source
Joint mouse–human phenome-wide association to test gene function and disease risk
Nature Communications, 2016 Phenome-wide association is a novel method that links sequence variants to a spectrum of phenotypes and diseases. Here the authors generate detailed mouse genetic and phenome data which links their phenome-wide association study (PheWAS) of mouse to ...
Xusheng Wang +25 more
doaj +1 more source
Environment International, 2019 The field of environmental epidemiology has been using “-omics” technologies, including the exposome, metabolome, and methylome, to understand the potential effects and biological pathways of a number of environmental pollutants. However, the majority of
Joseph M. Braun +3 more
doaj +1 more source