Results 41 to 50 of about 43,727 (248)
Advanced Science, EarlyView.This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong +7 more
wiley +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, EarlyView.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
A minimal biochemical route towards de novo formation of synthetic phospholipid membranes. [PDF]
, 2019 All living cells consist of membrane compartments, which are mainly composed of phospholipids. Phospholipid synthesis is catalyzed by membrane-bound enzymes, which themselves require pre-existing membranes for function.
Bhattacharya, Ahanjit +3 more
core +2 more sources
Advanced Science, EarlyView.Diagram of the reprogramming of FA metabolism mediated by LDHC4‐induced ACAA2 activity to promote TNBC progression. LDHC4 drives TNBC progression by enhancing ACAA2‐mediated fatty acid production. The resulting accumulation of FFAs stimulates autophagy and accelerates cell cycle progression, thereby promoting tumor growth.
Zhaolei Cui +10 more
wiley +1 more source
Capping protein modulates the dynamic behavior of actin filaments in response to phosphatidic Acid in Arabidopsis. [PDF]
, 2012 International audienceRemodeling of actin filament arrays in response to biotic and abiotic stimuli is thought to require precise control over the generation and availability of filament ends.
Blanchoin, Laurent +5 more
core +3 more sources
Advanced NanoBiomed Research, EarlyView.Perfluorocarbon‐based artificial oxygen carriers have long been of scientific interest for because they can be used as oxygen donors in medical applications. Lecithin‐modified nanoscale oxygen carriers (LENOX) are a newly designed nanoscaled emulsion based on perfluorodecalin, which is characterized by its compatibility with numerous clinically ...
Fabian Nocke +5 more
wiley +1 more source
Structured Lipids: Synthesis, Genetic Engineering, and Applications
Journal of the American Oil Chemists' Society, EarlyView.ABSTRACT Lipids are essential to the human body, but some can be harmful. As a result, current research focuses on structured lipids (SLs), which are engineered to have specific fatty acid arrangements. These structural modifications can enhance both nutritional and physical properties.
Chandu S. Madankar +5 more
wiley +1 more source
The tomato phosphatidylinositol-phospholipase C2 (SlPLC2) is required for defense gene induction by the fungal elicitor xylanase [PDF]
, 2014 The tomato [Solanum lycopersicum (Sl)] phosphatidylinositol-phospholipase C (PI-PLC) gene family is composed of six members, named SlPLC1 to SlPLC6, differentially regulated upon pathogen attack. We have previously shown that the fungal elicitor xylanase
Abd El Haliem, Ahmed +7 more
core +1 more source
Phosphatidic acid, phospholipase D and tumorigenesis
Advances in Biological Regulation, 2014 Phospholipase D (PLD) is a membrane protein with a double role: maintenance of the structural integrity of cellular or intracellular membranes and involvement in cell signaling through the product of the catalytic reaction, PA, and through protein-protein interaction with a variety of partners.
openaire +3 more sources
Arthritis &Rheumatology, Accepted Article.Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) immunoglobulin (Ig) G and IgM, and anti‐β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe +8 more
wiley +1 more source