Results 221 to 230 of about 391,487 (338)

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

iMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang, Jing Yang, Weiyao Zhang, Linghao Zhou, Chenxu Zhu, Xuguang Zhang, Yuejian Mao, Meiling Zhang   +7 more
wiley   +1 more source

Glycerophospholipid Profiles of <i>Allomyrina dichotoma</i> Larvae at Different Instars Based on Lipidomics and Transcriptomics Suggest a Promising Lipid Source. [PDF]

Insects
Fang K, Liu JN, Wang CX, Wang T, Pan Y, Wang S, Xi JH.   +6 more
europepmc   +1 more source

Inhibition of histamine secretion by wonmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells

, 1995
Hiroshi Yano, Satoshi Nakanishi, Yasuhisa Fukui, Yoshiaki Nonomura, Yuzuru Matsuda   +4 more
openalex   +1 more source

The p110δ Isoform of Phosphatidylinositol 3-Kinase Controls the Quality of Secondary Anti-Leishmania Immunity by Regulating Expansion and Effector Function of Memory T Cell Subsets [PDF]

, 2010
Dong Liu, Jude E. Uzonna
openalex   +1 more source

Oleoylethanolamide regulates intestinal stem cell activity and villus size via PPARα signaling pathway

iMetaOmics, EarlyView.
First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang, Lanmei Yin, Zhaobin Wang, Jun Li, Xianglin Zeng, Qiye Wang, Jianzhong Li, Kang Xu, Huansheng Yang, Yulong Yin   +9 more
wiley   +1 more source

Development of a highly efficient oil degumming process using a novel phosphatidylinositol-specific phospholipase C enzyme [PDF]

, 2017
Sebastián Cerminati, Florencia Eberhardt, Claudia Elena, Salvador Peirú, María Eugenia Castelli, Hugo G. Menzella   +5 more
openalex   +1 more source

From mechanism to phenotype: What fits in a basket trial

Epilepsia, EarlyView.
Kette D. Valente
wiley   +1 more source

Cell Toxicity and Autophagy in A549 Cells Treated With Surface‐Functionalized Graphene Derivatives

Journal of Applied Toxicology, EarlyView.
ABSTRACT Graphene oxide and its derivatives have unique physical and chemical properties with applications in many different fields. However, their biological effects and mechanisms of intracellular toxicity have not been completely clarified. In this study, we investigated the cytotoxic and autophagic activities of graphene oxide and its derivatives ...
Tae Yun Park, Soo Young Kim, Chang Seok Park, Won Young Kim, Jae‐Woo Jung, Jae‐Yeol Kim, Jong Wook Shin   +6 more
wiley   +1 more source

Electroacupuncture improves diabetes-associated cognitive impairment in rats: potential involvement of hippocampal insulin receptor substrates 1/phosphatidylinositol 3-kinase/protein kinase B signaling pathway activation. [PDF]

Neuroreport
Zhang L, Song H, Ye M, Kan W, Hu Y, Xie H, Yuan A.   +6 more
europepmc   +1 more source

Dietary Phosphatidylinositol [PDF]

, 2020
openaire   +1 more source