Results 41 to 50 of about 77,486 (386)
A Computational Study and Parameterisation of Phosphatidylinositol Phosphates for Lipid Simulations with AMBER [PDF]
arXiv, 2023 Phosphatidylinositol phosphates (PIPs) are membrane phospholipids that play crucial roles in a wide range of cellular functions. However, there is a dearth of experimental data in the literature on PIPs because their investigations are not always feasible and often prohibitively expensive.
arxiv
In silico Modeling of Itk Activation Kinetics in Thymocytes Suggests Competing Positive and Negative IP4 Mediated Feedbacks Increase Robustness [PDF]
PLOS ONE, Vol 8, Issue 9, Page e73937, September 2013, 2013 The inositol-phosphate messenger inositol(1,3,4,5)tetrakisphosphate (IP4) is essential for thymocyte positive selection by regulating plasma-membrane association of the protein tyrosine kinase Itk downstream of the T cell receptor (TCR). IP4 can act as a soluble analog of the phosphoinositide 3-kinase (PI3K) membrane lipid product phosphatidylinositol ...
arxiv +1 more source
Biochemical Journal, 1993 INTRODUCTION The protozoa are the most diverse and amongst the most ancient group of organisms in the eukaryotic kingdom (Sogin et al., 1989). Many of their members are parasitic and some, like those belonging to the family Trypanosomatidae (African ...
M. McConville, M. Ferguson
semanticscholar +1 more source
Toxoplasma gondii major surface antigen (SAG1): in vitro analysis of host cell binding [PDF]
, 2004 Previous studies have indicated that SAG1, the major surface molecule of the protozoan parasite Toxoplasma gondii, is an important attachment ligand for the host cell.
Millner, P.A. +2 more
core +1 more source
Mammalian Phosphatidylinositol 4‐Kinases [PDF]
IUBMB Life, 2003 AbstractThree phosphatidylinositol 4‐kinase isoforms, PI4K 230, 92 and 55 have been cloned and sequenced allowing a much wider characterization than the previously employed enzymological typing into type II and III enzymes. PI4K 230 and 92 contain a highly conserved catalytic core, PI4K55 one with a much lower degree of similarity.
Ludwig M G, Heilmeyer +4 more
openaire +3 more sources
Lipid Polarization during Cytokinesis
Cells, 2022 The plasma membrane of eukaryotic cells is composed of a large number of lipid species that are laterally segregated into functional domains as well as asymmetrically distributed between the outer and inner leaflets.
Govind Kunduri +2 more
doaj +1 more source
Cancer Research, 2009 The NF2 tumor suppressor gene encodes an intracellular membrane-associated protein, called merlin, which belongs to the band 4.1 family of cytoskeleton-associated proteins that link cell surface glycoproteins to the actin cytoskeleton.
M. Okada +5 more
semanticscholar +1 more source
Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis [PDF]
, 1995 Endocytosis of the fluid phase marker, horse radish peroxidase, into baby hamster kidney cells is inhibited by treatment of cells with the fungal metabolite wortmannin.
Clague, Michael J. +2 more
core +1 more source
Journal of Molecular Biology, 1997 Toxoplasma gondii is a ubiquitous parasitic protozoan causing congenital infection and severe encephalitis in the course of the acquired immunodeficiency syndrome. Glycosyl-phosphatidylinositols of T.
B. Striepen +8 more
semanticscholar +1 more source
Foods, 2023 In this work, an investigation using UHPLC-Q-Orbitrap-MS and multivariate statistics was conducted to obtain the lipid fingerprint of Camembert cheese and to explore its correlated variation with respect to X-ray irradiation treatment.
Michele Tomaiuolo +5 more
doaj +1 more source