Results 181 to 190 of about 110,140 (293)

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Heme and hemozoin induce platelet cell death through UPR-induced apoptosis and ferroptosis in vivax malaria. [PDF]

Blood Adv
Gomes MT, Medeiros-de-Moraes IM, Vieira-de-Abreu A, de Azevedo-Quintanilha IG, Fontes TM, de Brito Carneiro A, Azambuja P, Tolley ND, Rowley JW, Carpinter BA, Ferreira MU, Gonçalves RM, Rocha VN, Rosa Nascimento AL, Carvalho WA, Scopel KKG, Campbell RA, Bozza PT, Weyrich AS, Zimmerman GA, Lacerda MVG, Castro-Faria-Neto HC, Hottz ED.   +22 more
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Exogenous phosphatidylserine protects against mesenteric ischemia-reperfusion with associated Akt/mTOR pathway upregulation. [PDF]

Sci Rep
Hamaneh AM, Ghasemi M, Mehrabi MM, Ashtari S, Nejati F, Kazemzadeh H, Goudarzi R, Tavangar SM, Dehpour AR, Partoazar A.   +9 more
europepmc   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

Early synaptic pathology is associated with small tau aggregates in Alzheimer's disease. [PDF]

Acta Neuropathol
Fertan E, Kedia S, Nolan G, Meisl G, Cotton MW, Müller KH, Zhang Z, Muresan L, Quaegebeur A, Spillantini MG, Klenerman D.   +10 more
europepmc   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Enhancing IR‐MALDESI MSI Spatial Resolution Through Beam Constriction With a Ring‐Actuated Iris

Rapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Infrared matrix‐assisted laser desorption electrospray ionization (IR‐MALDESI) mass spectrometry imaging (MSI) enables label‐free, spatially resolved molecular analysis of biological tissues under ambient conditions. While improving spatial resolution is important for mapping fine tissue structures, mid‐infrared (IR) lasers are ...
Sarah M. Ashbacher, Seth M. Eisenberg, Alexander A. C. Wainwright, Aosheng Gu, Syeda N. Mahdia, R. J. Dwayne Miller, David C. Muddiman   +6 more
wiley   +1 more source

ROS-Mediated Apoptosis-Like Death Induced by Genistein in Candida albicans. [PDF]

Curr Microbiol
Kwun MS, Lee DG.
europepmc   +1 more source

Microglial Pruning of Excitatory Synapses in the Hippocampus Is Complement C3‐Independent in Physiological and Neuroinflammatory States

Glia, Volume 74, Issue 7, July 2026.
In development, microglia engulfment of hippocampal excitatory synapses is unperturbed in C3‐lacking mice. Peripheral inflammation induces a neuroinflammatory phenotype and synapse loss in the hippocampus independent of complement cascade activation. ABSTRACT A key feature of brain development is the refinement of exuberant synapses, known as synapse ...
Eric W. Salter, Ashish Kadia, Lijia Zhang, Jonathan S. Thacker, Sun‐Lim Choi, Liam T. Ralph, Gang Lei, Fuzi Jin, John Georgiou, Graham L. Collingridge   +9 more
wiley   +1 more source