Results 181 to 190 of about 79,638 (253)

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas   +5 more
wiley   +1 more source

Use of autoantigen-loaded phosphatidylserine-liposomes to arrest autoimmunity in type 1 diabetes

open access: yes
Introduction The development of new therapies to induce self-tolerance has been an important medical health challenge in type 1 diabetes. An ideal immunotherapy should inhibit the autoimmune attack, avoid systemic side effects and allow β -cell ...
Cano Sarabia, Mary.   +11 more
core  

Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min   +2 more
wiley   +1 more source

Toward a digital urinary biopsy for early risk stratification in diabetic kidney disease: Anchoring shed cells, vesicles, and cell‐free DNA to spatial kidney cell states

open access: yesClinical and Translational Medicine, Volume 16, Issue 11, November 2026.
In diabetic kidney disease, one urine specimen carries shed cells, extracellular vesicles and cell‐free DNA released along the whole nephron. Reading all three against spatial kidney atlases is proposed as a testable route to cell‐resolved, non‐invasive risk stratification, and the clinical outputs shown are not yet demonstrated.
Juan Wu, Ping Sheng, Ying Lu, Ke Chen
wiley   +1 more source

Rosa rugosa Root Extract as a Functional Food Ingredient, Mitigating UVB‐Induced Skin Aging Through MAPK/AP‐1 and AGE‐RAGE Pathway Modulation

open access: yesFood Science &Nutrition, Volume 14, Issue 11, November 2026.
Rosa rugosa root extract (RR‐r) attenuated UVB‐induced wrinkle formation and collagen degradation while improving skin hydration. Its photoprotective effects were associated with modulation of MAPK/AP‐1 and AGE‐RAGE signaling. ABSTRACT Rosa rugosa root extract (RR‐r) has been used in East Asian medicine to treat metabolic disorders, including diabetes ...
Min Ji Gu   +6 more
wiley   +1 more source

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