Results 191 to 200 of about 79,638 (253)

The Efferocytosis‐Driven Macrophage Polarization: A Concerto in the Tumor Immunosuppressive Microenvironment

MedComm, Volume 7, Issue 11, November 2026.
Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen, Chunzhi Wu, Changquan Huang, Hang Zhou   +3 more
wiley   +1 more source

Development of a FRET-Based Assay for Human Neutral Sphingomyelinase 2. [PDF]

Biochemistry
Aywa KM, Kappe C, Ghandour B, Gao S, Arenz C, Hannun YA, Airola MV.   +6 more
europepmc   +1 more source

Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu, Lei Wu, Kang Yang, Kang Xie, Tao Lu, Tiangxiang Huang, Dengfeng Wan, Tao Song, Longbo Zhang   +8 more
wiley   +1 more source

Prevalence and laboratory-associated variability of non-criteria antiphospholipid antibodies in women with pregnancy loss: A cross-sectional study. [PDF]

J Transl Autoimmun
Ding N, Wang R, Wang K, Li G, Wang F.
europepmc   +1 more source

Synergistic Effects of Thyroxine and Nano‐Melatonin on Post‐Thaw Sperm Quality, Antioxidant Defence and Fertility of Cryopreserved Simmental Bull Semen

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Effects of thyroxine (T) and nano‐melatonin (NM) supplementation on cryopreserved Simmental bull semen were evaluated. The combination of thyroxine (0.5 µg/dL) and nano‐melatonin (30 µg/dL) significantly improved post‐thaw sperm motility, membrane integrity, antioxidant status, and fertility while reducing oxidative stress and apoptosis. These findings
Marwa Abonagy, Ahmed Arisha, Maha Salama, Mohey Ashour, Mustafa Shukry, Sameh Shedeed, Ahmed Shehabeldin, Nagi El‐Shafai, Zein Ibrahim, Shawky Mahmoud, Michel Saad, Ahmed Alameen, Rasha Yassin Elkhidr, Osama Hassan Ali, Arafat Khalphallah, Enas Elmeligy, Khaled Abdulaziz Khesruf, Enas Ahmed Abdelhafez, Alaa Algabary   +18 more
wiley   +1 more source

Phosphatidylserine-everted erythrocyte membrane vesicles enhance efferocytosis and remodeling of vascular grafts. [PDF]

Nat Commun
Wang Z, Cheng Q, Zhou M, Feng K, Chen Q, Yuan Y, Zhang S, Kong D, Wang K, Wang J.   +9 more
europepmc   +1 more source

Functional Characterization and Application of Yarrowia lipolytica YlYxc1 for Enhanced Production of Sphingoid Bases

Microbial Biotechnology, Volume 19, Issue 11, November 2026.
YlYxc1, an ER‐associated alkaline ceramidase of Yarrowia lipolytica, has the hydrolytic activity of ceramides, which can be exploited as a metabolic engineering target to enhance long‐chain base production. ABSTRACT Long‐chain bases (LCBs; sphingoid bases), derived from ceramide metabolism, are valuable sphingolipid intermediates for industrial ...
Seo Hyeon Shin, Eun Joo Jeon, Hye Yun Moon, Ga Yeong Go, Young Seo Yoo, Jae Kyeong Lee, Che Ok Jeon, Hyun Ah Kang   +7 more
wiley   +1 more source

Induction of Methuosis in Breast Cancer Stem Cells by a Cobalt(III) Complex Evokes Immunotherapeutic Response

Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.
Cancer stem cells (CSCs) drive metastasis, relapse and resist conventional apoptosis‐inducing chemotherapies. We report a cobalt(III)‐cyclam complex with pyrene and diflunisal moieties that reduces the viability of breast CSCs at low micromolar concentrations.
Jiaxin Fang, Sijie Wen, Xiao Feng, Hao Ren, Kuldip Singh, Haihua Xiao, Lingpu Zhang, Kogularamanan Suntharalingam   +7 more
wiley   +2 more sources

Targeting Phosphatidylserine Synthesis for Tumor Cell Suppression in Esophageal Squamous Cell Carcinoma and Glioblastoma. [PDF]

Int J Mol Sci
Hu Y, Cui Y, Xu Z, Wu D, Yu X.
europepmc   +1 more source