Results 211 to 220 of about 73,519 (304)

Fish Sperm Subpopulations Detection, Separation, and Application: Current State and Trends

open access: yesReviews in Aquaculture, Volume 18, Issue 4, September 2026.
Modern advances in sperm biology highlight the necessity of recognising intra‐ejaculate heterogeneity as a central concept for advancing both the fundamental understanding of fertilisation processes and the development of artificial reproduction techniques in fishes. ABSTRACT Sperm subpopulations represent a fundamental manifestation of intra‐ejaculate
Viktoriya Dzyuba   +2 more
wiley   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

open access: yesTraffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby   +3 more
wiley   +1 more source

Enhancing IR‐MALDESI MSI Spatial Resolution Through Beam Constriction With a Ring‐Actuated Iris

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Infrared matrix‐assisted laser desorption electrospray ionization (IR‐MALDESI) mass spectrometry imaging (MSI) enables label‐free, spatially resolved molecular analysis of biological tissues under ambient conditions. While improving spatial resolution is important for mapping fine tissue structures, mid‐infrared (IR) lasers are ...
Sarah M. Ashbacher   +6 more
wiley   +1 more source

NLRC5‐Deficient Macrophages Promote a Tumor‐Permissive Phenotype via AXL‐ and MERTK‐Mediated Efferocytosis

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Defective NLRC5 signaling in macrophages drives TAM phenotype and anti‐inflammatory responses via STAT3/ERK, leading to tumor‐permissive conditions and gastric lymphoid neogenesis during Helicobacter infection. ABSTRACT The innate immune protein NLRC5 plays a key role in cancer immune surveillance.
Shambel Araya Haile   +7 more
wiley   +1 more source

Doxorubicin‐Induced Cytotoxicity in Adipose‐Derived Stem Cells Is Associated With Altered SAPK/JNK Signaling

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
This study investigated the effects of clinically relevant concentrations of doxorubicin (Dox; 5 μM), commonly used in anticancer therapy, on adipose‐derived stem cells (ADSCs). Dox induced ADSC dysfunction, characterized by reduced mitochondrial activity, apoptosis, oxidative stress, premature senescence, cytoskeletal alterations, and cell cycle ...
Aleksandra Skubis‐Sikora   +5 more
wiley   +1 more source

Interkingdom Endodontic Biofilm Supernatant Induces a Biphasic Inflammatory and Metabolic Transcriptional Response in Dental Pulp Stem Cells In Vitro

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objectives To investigate how soluble byproducts derived from a four‐species endodontic biofilm model impact the viability, transcriptomic profile, and inflammatory response of human dental pulp stem cells (DPSCs). Methods A sterile‐filtered supernatant was extracted from an established interkingdom endodontic biofilm model comprising ...
Saeed S. Alqahtani   +7 more
wiley   +1 more source

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