Results 201 to 210 of about 110,140 (293)

Outer membrane vesicles hijack TIM-1 for cellular uptake. [PDF]

PLoS Pathog
MacNair CR, Tiku V, Cao S, Sanchez AD, Udayasuryan B, Kroll KT, Singh A, Tan MW.   +7 more
europepmc   +1 more source

Inhibition of PLA2G15 Alleviates Palmitic Acid‐Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 2, June 2026.
LMP is responsible for lysosomal dysfunction in IDD. The lipid composition changes in the lysosomal membrane, mediated by PLA2G15, are the cause of LMP. The C/EBPα significantly promotes PLA2G15 expression under PA overload stress. Inhibition of PLA2G15 alleviates PA‐induced LMP by inhibiting the hydrolysis of lysosomal membrane phospholipids. ABSTRACT
Liqun Duan, Jiang Jiang, Shuangshuang Tu, Chuanfu Li, Yijun Dong, Yongjin Li, Wenzhi Zhang, Xi Chen   +7 more
wiley   +1 more source

Phosphatidylserine-Dependent Clearance of Damaged Red Blood Cells by Liver Sinusoidal Endothelial Cells in Alcohol-Related Liver Disease. [PDF]

Biology (Basel)
Li S, Zheng C, Zha X, Mueller J, Dropmann A, Hammad S, Dooley S, Mueller S.   +7 more
europepmc   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Differential sensitivity of leukocyte populations to <i>Staphylococcus aureus</i> biofilm. [PDF]

Infect Immun
Brandquist ND, Kielian T.
europepmc   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

The diagnostic and prognostic values of non-criteria antiphospholipid antibodies in obstetric antiphospholipid syndrome. [PDF]

BMC Pregnancy Childbirth
Han J, Cai R, Chen Q, Huang W, Qin L, Zeng R, Gao R.   +6 more
europepmc   +1 more source

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

MedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge, Liu Yu, Jiahe Lu, Aihetaimujiang Anwaier, Xiyue Xiao, Yonghao Chen, Dingwei Ye, Hailiang Zhang, Wenhao Xu, Wenbin Dai   +9 more
wiley   +1 more source

Integrating Anti-Phosphatidylserine/Prothrombin Antibodies Testing into Antiphospholipid Syndrome Diagnostics: A Multidomain, Expert Perception-Based Health Technology Assessment. [PDF]

Diagnostics (Basel)
Cioffi M, Oddone V, Radin M, Cecchi I, Barinotti A, Foddai SG, Di Gaetano N, Pagani N, Colmegna A, Baldovino S, Fenoglio R, Roccatello D, Sciascia S.   +12 more
europepmc   +1 more source

Phosphatidylserin-Antikörper [PDF]

, 2019
openaire   +1 more source