Results 81 to 90 of about 41,016 (180)

Metabolic Labeling of Phosphatidylethanolamine Lipids in Cells Using Clickable Ethanolamine Analogs

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
This work describes the metabolic labeling of phosphatidylethanolamine (PE) lipids using clickable ethanolamine substrate analogs. Post‐derivatization of tagged PE in cells via click chemistry enabled detection using fluorescence microscopy, mass spectrometry, and TLC imaging.
Robert J. Maraski, Jinchao Lou, Todd B. Reynolds, Michael D. Best   +3 more
wiley   +1 more source

Pathways of phosphatidylcholine biosynthesis in the yeast S. cerevisiae.

, 2015
Cct1, cholinephosphate cytidylyltransferase; CDP-Cho, cytidine-diphosphocholine, CDP-Etn, cytidine-diphosphoethanolamine; Cho, Choline; Cho2, phosphatidylethanolamine methyltransferase; Cho-P, phosphocholine; Cki1, choline kinase; Cpt1 ...
Claudia Ramprecht (779344), Günther Zellnig (779345), Erich Leitner (436479), Ariane Fankl (779343), Vid V. Flis (779342), Günther Daum (469693), Albin Hermetter (440005)   +6 more
core   +1 more source

Prevalence of autoantibodies to the 65- and 67-kD isoforms of glutamate decarboxylase in insulin-dependent diabetes mellitus [PDF]

, 1993
We investigated the presence of autoantibodies to baculovirus-expressed human recombinant 65- and 67-kD isoforms of glutamate decarboxylase (GAD65 and GAD67) in insulin-dependent diabetes mellitus (IDDM).
Haubruck, Heinz, H Haubruck, Seißler, Jochen, S Wolfahrt, Heinze, Eberhard, R Holl, Wolfahrt, S., W Northemann, Mauch, Ludwig, W Richter, Northemann, Wolfgang, L Mauch, J Seissler, Richter, Wiltrud, J Amann, Holl, Reinhard, S Bieg, Bieg, Sabine, Amann, J., Scherbaum, Werner A., E Heinze   +20 more
core   +1 more source

Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system

Reproductive Biology and Endocrinology, 2009
Hazardous health effects stemming from exposure to radiofrequency electromagnetic waves (RF-EMW) emitted from cell phones have been reported in the literature. However, the cellular target of RF-EMW is still controversial.
Kesari Kavindra K, Desai Nisarg R, Agarwal Ashok   +2 more
doaj   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source

Lipid Anchoring of Archaeosortase Substrates and Midcell Growth in Haloarchaea

mBio, 2020
The archaeal cytoplasmic membrane provides an anchor for many surface proteins. Recently, a novel membrane anchoring mechanism involving a peptidase, archaeosortase A (ArtA), and C-terminal lipid attachment of surface proteins was identified in the model
Mohd Farid Abdul-Halim, Stefan Schulze, Anthony DiLucido, Friedhelm Pfeiffer, Alexandre Wilson Bisson Filho, Mechthild Pohlschroder   +5 more
doaj   +1 more source

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

Lipidomic Alterations in the Mitochondria of Aged Parkin Null Mice Relevant to Autophagy

Frontiers in Neuroscience, 2019
Mitochondrial quality control is important in neurological diseases, but in genetic Parkinson’s disease caused by mutations in PINK and parkin mitochondrial degradation through autophagy is crucial. Reductions in autophagy and mitophagy are implicated in
Angel Gaudioso, Patricia Garcia-Rozas, Maria Jose Casarejos, Oscar Pastor, Jose Antonio Rodriguez-Navarro   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, Volume 600, Issue 14, Page 1992-2011, July 2026.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source