Results 231 to 240 of about 18,679,675 (294)

European Consortium for Lipodystrophies consensus definition and classification framework for monogenic lipodystrophy

Journal of Internal Medicine, EarlyView.
Abstract Lipodystrophy comprises a heterogeneous group of disorders characterized by reduced adipose tissue often associated with severe metabolic complications. Lipodystrophy may be genetic, acquired, or secondary to medical therapies initiated for other conditions.
Robert K. Semple, Martin Wabitsch, Baris Akinci, Saif Alyaarubi, Marjoleine F. Broekema, Rebecca J. Brown, Giovanni Ceccarini, Carolina Cecchetti, Solaf M. Elsayed, Antía Fernández‐Pombo, Alessandra Gambineri, Ingrid M. Jazet, Lotte Kleinendorst, Konstanze Miehle, Elif A. Oral, Flavia Prodam, Ferruccio Santini, David B. Savage, Nadia Shaukat Ali, Ekaterina Sorkina, Magdalena Szopa, Marie‐Christine Vantyghem, Camille Vatier, Corinne Vigouroux, Julia von Schnurbein, David Araújo‐Vilar   +25 more
wiley   +1 more source

Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum

Molecular Microbiology, EarlyView.
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol, Dominik Šťastný, J. Pedro Fernandez‐Murray, Christopher R. McMaster, Peter Griač, Dave Richard   +5 more
wiley   +1 more source

Genetic Etiologies and Outcomes in Malignancy and Mortality in Activated Phosphoinositide 3-Kinase Delta Syndrome: A Systematic Review. [PDF]

Adv Ther
Büsch K, Memmott HL, McLaughlin HM, Upton JEM, Harrington A.   +4 more
europepmc   +1 more source

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

[Retracted] Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3‑kinase/protein kinase B signaling pathway in mice during cardiac surgery. [PDF]

Mol Med Rep
Pi Z, Lin H, Yang J.
europepmc   +1 more source

Treatment strategies targeting the phosphoinositide 3-kinase/protein kinase B/mechanistic target of rapamycin pathway against triple-negative breast cancer. [PDF]

World J Clin Oncol
Ni CX, Xu JJ, Pang Y, Xu JJ.
europepmc   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Correction: Inhibition of cc chemokine receptor 10 ameliorates osteoarthritis via inhibition of the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin pathway. [PDF]

J Orthop Surg Res
Luo Y, Zhou F, Wang X, Yang R, Li Y, Wu X, Ye B.   +6 more
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Correction: EBV-positive diffuse large B cell lymphoma secondary to activated phosphoinositide 3 kinase δ syndrome type 1 (APDS1): a case report and literature review. [PDF]

Front Immunol
Xiang QY, Zuo M, Zhou JH, Feng C.
europepmc   +1 more source