Results 11 to 20 of about 37,565 (330)
PHOSPHOINOSITIDE KINASES [PDF]
Annual Review of Biochemistry, 1998 Phosphatidylinositol, a component of eukaryotic cell membranes, is unique among phospholipids in that its head group can be phosphorylated at multiple free hydroxyls. Several phosphorylated derivatives of phosphatidylinositol, collectively termed phosphoinositides, have been identified in eukaryotic cells from yeast to mammals.
D A, Fruman, R E, Meyers, L C, Cantley
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eLife, 2022 Membrane lipids, and especially phosphoinositides, are differentially enriched within the eukaryotic endomembrane system. This generates a landmark code by modulating the properties of each membrane.
Alexis Lebecq +14 more
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Phosphoinositide Profile of the Mouse Retina
Cells, 2020 Phosphoinositides are known to play multiple roles in eukaryotic cells. Although dysregulation of phosphoinositide metabolism in the retina has been reported to cause visual dysfunction in animal models and human patients, our understanding of the ...
Stella Finkelstein +5 more
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European Journal of Histochemistry, 2009 Phosphoinositide 3-kinases (PI 3-kinases), a class of enzymes implicated in growth factor-induced mitogenic response and many other intracellular signalling pathways, act by phosphorylation at the D-3’-OH position of the myo-inositol ring of ...
V. Bertagnolo +4 more
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Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily. [PDF]
, 2015 The human genome encodes about 285 proteins that contain at least one annotated pleckstrin homology (PH) domain. As the first phosphoinositide binding module domain to be discovered, the PH domain recruits diverse protein architectures to cellular ...
Abagyan, Ruben +3 more
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Animal cell cytokinesis: the role of dynamic changes in the plasma membrane proteome and lipidome [PDF]
, 2016 In animal cells, cytokinesis is characterised by the formation of the mitotic spindle that signals the assembly of an actomyosin ring between the spindle poles.
Gould, Gwyn W.
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Biology Open, 2022 Human brain development is a complex process where multiple cellular and developmental events are coordinated to generate normal structure and function.
Bilal M. Akhtar +8 more
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Phosphoinositides and phagocytosis [PDF]
The Journal of Cell Biology, 2001 Phosphoinositide 3 kinases (PI3Ks)**Abbreviation used in this paper: PI3K, phosphoinositide 3 kinase. are known as regulators of phagocytosis. Recent results demonstrate that class I and III PI3Ks act consecutively in phagosome formation and maturation, and that their respective products, phosphatidylinositol 3,4,5-trisphosphate (PI[3,4,5]P3) and ...
Gillooly, David J. +2 more
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Membrane-associated proteins in giardia lamblia [PDF]
, 2018 The manner in which membrane-associated proteins interact with the membrane defines their subcellular fate and function. This interaction relies on the characteristics of the proteins, their journey after synthesis, and their interaction with other ...
Feliziani, Constanza +2 more
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Diverse Physiological Functions of FAB1 and Phosphatidylinositol 3,5-Bisphosphate in Plants
Frontiers in Plant Science, 2019 Biological membranes are predominantly composed of structural glycerophospholipids such as phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol. Of the membrane glycerophospholipids, phosphatidylinositol (PtdIns) and its phosphorylated
Tomoko Hirano, Masa H. Sato
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