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Bio-ProtocolPhosphoinositides are rare membrane lipids that mediate cell signaling and membrane dynamics. PI(4)P and PI(3)P are two major phosphoinositides crucial for endolysosomal functions and dynamics, making them the lipids of interest in many studies.
Wei Sheng Yap, Peter Kim, Maxime Boutry
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Lipid dynamics at dendritic spines
Frontiers in Neuroanatomy, 2014 Dynamic changes in the structure and composition of the membrane protrusions forming dendritic spines underlie memory and learning processes. In recent years a great effort has been made to characterize in detail the protein machinery that controls spine
Carlos Gerardo Dotti +2 more
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, 2015 En interagissant spécifiquement avec des protéines, les phosphoinositides organisent de manière spatio-temporelle la formation de complexes protéiques impliqués dans le contrôle de la signalisation intracellulaire, du trafic vésiculaire ou de l ...
Bernard Payrastre, Julien Viaud
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Pairing phosphoinositides with calcium ions in endolysosomal dynamics [PDF]
, 2011 The direction and specificity of endolysosomal membrane trafficking is tightly regulated by various cytosolic and membrane-bound factors, including soluble NSF attachment protein receptors (SNAREs), Rab GTPases, and phosphoinositides. Another trafficking
Wang, Xiang +5 more
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Phosphatidylinositolphosphate phosphatase activities and cancer
Journal of Lipid Research, 2016 Signaling through the phosphoinositide 3-kinase pathways mediates the actions of a plethora of hormones, growth factors, cytokines, and neurotransmitters upon their target cells following receptor occupation.
Simon A. Rudge, Michael J.O. Wakelam
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Phosphoinositide-signaling is one component of a robust plant defense response.
Frontiers in Plant Science, 2014 The phosphoinositide pathway and inositol-1,4,5-triphosphate (InsP3) have been implicated in plant responses to many abiotic stresses; however, their role in response to biotic stress is not well characterized.
Imara Yasmin Perera +4 more
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Frontiers in Cell and Developmental Biology, 2023 Phosphoinositides serve as essential players in numerous biological activities and are critical for overall cellular function. Due to their complex chemical structures, localization, and low abundance, current challenges in the phosphoinositide field ...
Alicia Llorente +2 more
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Phosphoinositides in cell architecture
, 2011 Inositol phospholipids have been implicated in almost all aspects of cellular physiology including spatiotemporal regulation of cellular signaling, acquisition of cellular polarity, specification of membrane identity, cytoskeletal dynamics, and ...
Shewan, Annette +5 more
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Frontiers in Immunology, 2019 Taurine may alleviate the inflammatory injury induced by Streptococcus uberis (S. uberis) infection by regulating intracellular Ca2+ levels. However, the underlying mechanisms remain unclear. Infection leads to subversion of phosphoinositides (PIs) which
Ming Li +7 more
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Tamas Balla: Leading the way with phosphoinositides
, 2018 Balla investigates how phosphoinositides control trafficking and signaling.
Marie Anne O’Donnell
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