Results 31 to 40 of about 27,020 (299)

Phosphoinositides in the kidney

open access: yesJournal of Lipid Research, 2019
Phosphoinositides (PIs) play pivotal roles in the regulation of many biological processes. The quality and quantity of PIs is regulated in time and space by the activity of PI kinases and PI phosphatases. The number of PI-metabolizing enzymes exceeds the
Leopoldo Staiano   +1 more
doaj   +1 more source

The emerging role of phosphoinositide clustering in intracellular trafficking and signal transduction [version 1; referees: 4 approved]

open access: yesF1000Research, 2016
Phosphoinositides are master regulators of multiple cellular processes: from vesicular trafficking to signaling, cytoskeleton dynamics, and cell growth.
Laura Picas   +2 more
doaj   +1 more source

Phosphatidylinositol 4,5-Bisphosphate Mediates the Co-Distribution of Influenza A Hemagglutinin and Matrix Protein M1 at the Plasma Membrane

open access: yesViruses, 2022
The fully assembled influenza A virus (IAV) has on its surface the highest density of a single membrane protein found in nature—the glycoprotein hemagglutinin (HA) that mediates viral binding, entry, and assembly.
Prakash Raut   +5 more
doaj   +1 more source

Phosphoinositides and engulfment [PDF]

open access: yes, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108686/1/cmi12334 ...
Swanson, Joel A.
core   +1 more source

Lipid dynamics at dendritic spines

open access: yesFrontiers in Neuroanatomy, 2014
Dynamic changes in the structure and composition of the membrane protrusions forming dendritic spines underlie memory and learning processes. In recent years a great effort has been made to characterize in detail the protein machinery that controls spine
Carlos Gerardo Dotti   +2 more
doaj   +1 more source

Phosphoinositides and Photoreceptors [PDF]

open access: yesMolecular Neurobiology, 2011
The importance of phosphoinositides (phosphorylated phosphatidyl inositol derivatives, PIs) for normal cellular function cannot be overstated. Although they represent a small fraction of the total phospholipid within the cell, they are essential regulators of many cellular functions.
openaire   +2 more sources

Phosphoinositides in New Spaces

open access: yesCold Spring Harbor Perspectives in Biology, 2023
Phosphoinositides (PIs) are phospholipids derived from phosphatidylinositol. PIs are regulated via reversible phosphorylation, which is directed by the opposing actions of PI kinases and phosphatases. PIs constitute a minor fraction of the total cellular lipid pool but play pleiotropic roles in multiple aspects of cell biology.
Elizabeth Michele Davies   +2 more
openaire   +3 more sources

Targeting phosphoinositide signaling in cancer: relevant techniques to study lipids and novel avenues for therapeutic intervention

open access: yesFrontiers in Cell and Developmental Biology, 2023
Phosphoinositides serve as essential players in numerous biological activities and are critical for overall cellular function. Due to their complex chemical structures, localization, and low abundance, current challenges in the phosphoinositide field ...
Alicia Llorente   +2 more
doaj   +1 more source

Membrane-associated proteins in giardia lamblia [PDF]

open access: yes, 2018
The manner in which membrane-associated proteins interact with the membrane defines their subcellular fate and function. This interaction relies on the characteristics of the proteins, their journey after synthesis, and their interaction with other ...
Feliziani, Constanza   +2 more
core   +1 more source

Phosphatidylinositolphosphate phosphatase activities and cancer

open access: yesJournal of Lipid Research, 2016
Signaling through the phosphoinositide 3-kinase pathways mediates the actions of a plethora of hormones, growth factors, cytokines, and neurotransmitters upon their target cells following receptor occupation.
Simon A. Rudge, Michael J.O. Wakelam
doaj   +1 more source

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