Results 11 to 20 of about 13,190 (254)

Dysregulation of Phosphoinositide 5-Phosphatases and Phosphoinositides in Alzheimer's Disease [PDF]

Frontiers in Neuroscience, 2021
info:eu-repo/semantics ...
Ando, Kunie, Erneux, Christophe, Homa, Mégane, Houben, Sarah, De Fisenne, Marie-Ange, Brion, Jean Pierre, Leroy, Karelle   +6 more
openaire   +5 more sources

PHOSPHOINOSITIDE KINASES [PDF]

Annual Review of Biochemistry, 1998
Phosphatidylinositol, a component of eukaryotic cell membranes, is unique among phospholipids in that its head group can be phosphorylated at multiple free hydroxyls. Several phosphorylated derivatives of phosphatidylinositol, collectively termed phosphoinositides, have been identified in eukaryotic cells from yeast to mammals.
D A, Fruman, R E, Meyers, L C, Cantley
openaire   +2 more sources

The Arabidopsis SAC9 enzyme is enriched in a cortical population of early endosomes and restricts PI(4,5)P2 at the plasma membrane

eLife, 2022
Membrane lipids, and especially phosphoinositides, are differentially enriched within the eukaryotic endomembrane system. This generates a landmark code by modulating the properties of each membrane.
Alexis Lebecq, Mehdi Doumane, Aurelie Fangain, Vincent Bayle, Jia Xuan Leong, Frédérique Rozier, Maria del Marques-Bueno, Laia Armengot, Romain Boisseau, Mathilde Laetitia Simon, Mirita Franz-Wachtel, Boris Macek, Suayib Üstün, Yvon Jaillais, Marie-Cécile Caillaud   +14 more
doaj   +1 more source

Phosphoinositide Profile of the Mouse Retina

Cells, 2020
Phosphoinositides are known to play multiple roles in eukaryotic cells. Although dysregulation of phosphoinositide metabolism in the retina has been reported to cause visual dysfunction in animal models and human patients, our understanding of the ...
Stella Finkelstein, Sidney M. Gospe, Kai Schuhmann, Andrej Shevchenko, Vadim Y. Arshavsky, Ekaterina S. Lobanova   +5 more
doaj   +1 more source

Phosphoinositide 3-kinase is associated to the nucleus of HL-60 cells and is involved in their ATRA-induced granulocytic differentiation

European Journal of Histochemistry, 2009
Phosphoinositide 3-kinases (PI 3-kinases), a class of enzymes implicated in growth factor-induced mitogenic response and many other intracellular signalling pathways, act by phosphorylation at the D-3’-OH position of the myo-inositol ring of ...
V. Bertagnolo, A. Gonelli, F. Brugnoli, L.M. Neri, M. Marchisio   +4 more
doaj   +3 more sources

Phosphoinositides in Cell Architecture [PDF]

Cold Spring Harbor Perspectives in Biology, 2011
Inositol phospholipids have been implicated in almost all aspects of cellular physiology including spatiotemporal regulation of cellular signaling, acquisition of cellular polarity, specification of membrane identity, cytoskeletal dynamics, and regulation of cellular adhesion, motility, and cytokinesis.
Shewan, Annette, Eastburn, Dennis J., Mostov, Keith   +2 more
openaire   +5 more sources

Phosphoinositides and Photoreceptors [PDF]

Molecular Neurobiology, 2011
The importance of phosphoinositides (phosphorylated phosphatidyl inositol derivatives, PIs) for normal cellular function cannot be overstated. Although they represent a small fraction of the total phospholipid within the cell, they are essential regulators of many cellular functions.
openaire   +2 more sources

A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome

Biology Open, 2022
Human brain development is a complex process where multiple cellular and developmental events are coordinated to generate normal structure and function.
Bilal M. Akhtar, Priyanka Bhatia, Shubhra Acharya, Sanjeev Sharma, Yojet Sharma, Aswathy Bhuvanendran Nair Suseela Devi, Kavina Ganapathy, Anil Vasudevan, Padinjat Raghu   +8 more
doaj   +1 more source

Diverse Physiological Functions of FAB1 and Phosphatidylinositol 3,5-Bisphosphate in Plants

Frontiers in Plant Science, 2019
Biological membranes are predominantly composed of structural glycerophospholipids such as phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol. Of the membrane glycerophospholipids, phosphatidylinositol (PtdIns) and its phosphorylated
Tomoko Hirano, Masa H. Sato
doaj   +1 more source

Effects of thyroxine and 1-methyl, 2-mercaptoimidazol on phosphoinositides synthesis in rat liver

Lipids in Health and Disease, 2004
Background Phosphoinositides mediate one of the intracellular signal transduction pathways and produce a class of second messengers that are involved in the action of hormones and neurotransmitters on target cells.
Krasilnikova Oksana A, Babenko Nataliya A   +1 more
doaj   +1 more source