Results 11 to 20 of about 27,357 (285)

Key role of polyphosphoinositides in dynamics of fusogenic nuclear membrane vesicles. [PDF]

PLoS ONE, 2011
The role of phosphoinositides has been thoroughly described in many signalling and membrane trafficking events but their function as modulators of membrane structure and dynamics in membrane fusion has not been investigated.
Vanessa Zhendre, Axelle Grélard, Marie Garnier-Lhomme, Sébastien Buchoux, Banafshé Larijani, Erick J Dufourc   +5 more
doaj   +1 more source

Bulk and single-cell transcriptomics reveal prognostic signatures of phosphoinositide metabolism in lung adenocarcinoma. [PDF]

Sci Rep
Zhou L, Lei P, Luo Z, Xiao J, Chen Z.
europepmc   +3 more sources

Phosphoinositides and host-pathogen interactions. [PDF]

, 2015
International audiencePhosphoinositides control key cellular processes including vesicular trafficking and actin polymerization. Intracellular bacterial pathogens manipulate phosphoinositide metabolism in order to promote their uptake by target cells and
Pizarro-Cerdá, Javier, Andreas Kühbacher, Pascale Cossart, Kühbacher, Andreas, Cossart, Pascale, Javier Pizarro-Cerdá   +5 more
core   +2 more sources

The Arabidopsis SAC9 enzyme is enriched in a cortical population of early endosomes and restricts PI(4,5)P2 at the plasma membrane

eLife, 2022
Membrane lipids, and especially phosphoinositides, are differentially enriched within the eukaryotic endomembrane system. This generates a landmark code by modulating the properties of each membrane.
Alexis Lebecq, Mehdi Doumane, Aurelie Fangain, Vincent Bayle, Jia Xuan Leong, Frédérique Rozier, Maria del Marques-Bueno, Laia Armengot, Romain Boisseau, Mathilde Laetitia Simon, Mirita Franz-Wachtel, Boris Macek, Suayib Üstün, Yvon Jaillais, Marie-Cécile Caillaud   +14 more
doaj   +1 more source

Phosphoinositide Profile of the Mouse Retina

Cells, 2020
Phosphoinositides are known to play multiple roles in eukaryotic cells. Although dysregulation of phosphoinositide metabolism in the retina has been reported to cause visual dysfunction in animal models and human patients, our understanding of the ...
Stella Finkelstein, Sidney M. Gospe, Kai Schuhmann, Andrej Shevchenko, Vadim Y. Arshavsky, Ekaterina S. Lobanova   +5 more
doaj   +1 more source

Phosphoinositide 3-kinase is associated to the nucleus of HL-60 cells and is involved in their ATRA-induced granulocytic differentiation

European Journal of Histochemistry, 2009
Phosphoinositide 3-kinases (PI 3-kinases), a class of enzymes implicated in growth factor-induced mitogenic response and many other intracellular signalling pathways, act by phosphorylation at the D-3’-OH position of the myo-inositol ring of ...
V. Bertagnolo, A. Gonelli, F. Brugnoli, L.M. Neri, M. Marchisio   +4 more
doaj   +3 more sources

Synthetic phosphoinositides as substrate analogs and ligands of phospholipase C.

, 2001
Synthetic phosphoinositides as substrate analogs and ligands of phospholipase ...
Cornelia. Mihai (7958867)
core   +6 more sources

Phosphoinositides regulate ion channels [PDF]

, 2015
Phosphoinositides serve as signature motifs for different cellular membranes and often are required for the function of membrane proteins. Here, we summarize clear evidence supporting the concept that many ion channels are regulated by membrane ...
Kruse, Martin, Vivas, Oscar, Suh, Byung-Chang, Dickson, Eamonn J, Suh, Byung Chang, Hille, Bertil, Dickson, Eamonn J.   +6 more
core   +1 more source

Functional insights into Plasmodium actin-depolymerizing factor interactions with phosphoinositides. [PDF]

J Biol Chem
Malaria is caused by protozoan parasites, Plasmodium spp., that belong to the phylum Apicomplexa. The life cycle of these parasites depends on two different hosts; the definitive host, or vector, is a mosquito, and the intermediate host is a vertebrate ...
Lasiwa D, Kursula I.
europepmc   +2 more sources

A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome

Biology Open, 2022
Human brain development is a complex process where multiple cellular and developmental events are coordinated to generate normal structure and function.
Bilal M. Akhtar, Priyanka Bhatia, Shubhra Acharya, Sanjeev Sharma, Yojet Sharma, Aswathy Bhuvanendran Nair Suseela Devi, Kavina Ganapathy, Anil Vasudevan, Padinjat Raghu   +8 more
doaj   +1 more source