Results 221 to 230 of about 37,565 (330)

Phosphoinositide Signaling [PDF]

Chemistry & Biology, 2004
openaire   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Optimizing PH Domain-Based Biosensors for Improved Plasma Membrane PIP₃ Measurements in Mammalian Cells. [PDF]

Cells
Damouni A, Tóth DJ, Schönek A, Kasbary A, Boros AP, Várnai P.   +5 more
europepmc   +1 more source

Development and Validation of a Urinary Exosomal miRNA Diagnostic Panel for Early Detection of Esophageal Cancer

Cancer Science, EarlyView.
Using a machine learning–based approach in a multi‐institutional prospective cohort, we identified a robust miRNA signature that demonstrated high diagnostic accuracy for esophageal squamous cell carcinoma. Our 57‐miRNA panel achieved an AUC of 0.90 in the proof‐of‐concept cohort and 0.85 in an independent validation cohort, with a sensitivity of 84 ...
Tatsuro Murano, Hiroki Yamashita, Yuki Kano, Ken Takeuchi, Takayuki Amano, Takanobu Yoshimoto, Mayuko Otomo, Hisashi Fujiwara, Shin Namiki, Hiroki Yamaguchi, Yoriko Ando, Yumi Nishiyama, Mika Mizunuma, Yuki Ichikawa, Tomonori Yano   +14 more
wiley   +1 more source

Non-erythrocyte spectrin network preferentially stabilizes flat membrane and enhances cell stiffness. [PDF]

RSC Adv
Komikawa T, Miyake T, Morooka M, Kawakami R, Saito S, Critchley K, Evans SD, Okochi M, Tanaka M.   +8 more
europepmc   +1 more source

Regulation of the phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by a pertussis toxin-sensitive guanine nucleotide-binding protein. Evaluation of its contribution to platelet activation and comparisons with the adenylate cyclase inhibitory protein, Gi.

, 1986
Lawrence F. Brass, Michael Laposata, H S Banga, S E Rittenhouse   +3 more
openalex   +1 more source

Clinical Applications of Phosphoproteomics: Illuminating Cancer Signaling and Enabling Rational Therapeutic Strategies

Cancer Science, EarlyView.
Mass spectrometry‐based phosphoproteomics for mechanistic dissection of cancer signaling pathways and uncovering therapeutic vulnerabilities. ABSTRACT Protein phosphorylation is a central post‐translational modification regulating cellular signaling, frequently dysregulated in cancer.
Hirokazu Shoji, Narikazu Boku, Jun Adachi   +2 more
wiley   +1 more source

Single-Molecule Imaging and Super-Resolution Microscopy of Lipid Domains in Cell Membranes Using Lipid-Binding Proteins and Fluorophore-Conjugated Lipid Analogs. [PDF]

Membranes (Basel)
Mori T, Suzuki KGN.
europepmc   +1 more source

A Role for the Phosphoinositide Lipid Kinase PI4KIIIbeta in Breast Oncogenesis and Akt Activation

, 2014
Anne A. Morrow
openalex   +1 more source

Characterization of p87PIKAP, a Novel Regulatory Subunit of Phosphoinositide 3-Kinase γ That Is Highly Expressed in Heart and Interacts with PDE3B [PDF]

, 2006
Philipp Voigt, Martin B. Dorner, Michael Schaefer   +2 more
openalex   +1 more source