Results 121 to 130 of about 1,619,431 (240)
Lipoprotein-associated phospholipase A2, vascular inflammation and cardiovascular risk prediction
Krishnankutty SudhirStanford University Medical Center, Stanford, CA, USAAbstract: Circulating lipoprotein-associated phospholipase A2 (Lp-PLA2) is a marker of inflammation that plays a critical role in atherogenesis; its inhibition may have ...
Krishnankutty Sudhir
core
Oncogenic action of phospholipase A2 in prostate cancer
Mortality from prostate cancer is a result of progression of cancer cells to become androgen-refractory and metastatic. Eicosanoid products of the cyclooxygenase (COX) and lipoxygenase (LOX) pathways are important mediators of the proliferation of ...
Sved, Paul +8 more
core +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Phospholipase A2 Activity Modulates “Ischemic Effect” in Pig Skin
The level of cyclic AMP in the epidermis rapidly increase within 15 min after separation from the in vivo condition. This phenomenon is the so-called “ischemic effect.” In order to elucidate the possible mechanism of the ischemic effect, the effects of ...
Miura, Yusho +2 more
core +1 more source
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source
Membrane binding and activation mechanisms of phospholipase A2 and 5-Lipoxygenase.
Membrane binding and activation mechanisms of phospholipase A2 and 5 ...
Gihani Thakshala. Wijewickrama (7974932)
core +3 more sources
Idiopathic membranous nephropathy (IMN) is characterized by anti-phospholipase A2 receptor (PLA2R) antibodies, yet current detection methods lack sensitivity or are invasive. We developed a chemiluminescent assay to address these limitations. Three PLA2R
Jiangjian Liu +3 more
doaj +1 more source
In this review, we provide an overview of selected historical antidotes against snakebite envenomation used in early modern Europe. Then, the evidence‐based antivenom activity of some natural compounds is discussed as resulting from more than two decades of research studies.
Elisa Bianconi +3 more
wiley +1 more source
Membranous glomerulonephritis (MGN) is the most common cause of nephrotic syndromein adults worldwide; however, it accounts for only 1.5% to 9% of cases of pediatricnephrotic syndrome.
Kumar, Mritunjay +3 more
core +1 more source
Stimuli‐Responsive Lipid‐Based Nanocarriers for Antimicrobial Therapy
This manuscript demonstrated, through a scoping review of the literature, that modifying lipid nanocarriers with organic and inorganic excipients is a promising alternative to increase in vitro drug release of antimicrobial compounds under the studied stimulus and significantly enhance in vitro and in vivo antimicrobial activity compared to isolated ...
Brenda Maria Silva Bezerra +5 more
wiley +1 more source

