Results 111 to 120 of about 163,724 (193)

Effect of 5mM PBA on the expression of thapsigargin-inducible (ER-stress) genes in C2C12 myotubes.

, 2018
(A) mRNA abundance of Phosphoserine aminotransferase 1 (PSAT1), Phosphoserine phosphatase (PSPH), 3-Phosphoglycerate dehydrogenase (PHGDH), asparagine synthetase (ASNS), mitochondrial phosphoenolpyruvate carboxykinase (PCK2), Activating transcription ...
Zoe C. T. R. Daniel (5566262), Tim Parr (668636), Francis J. P. Ebling (160811), Madelaine C. Brearley (5566265), Jo E. Lewis (3779404), Sarah Jones (400393), David M. Brown (475802), John M. Brameld (668635)   +7 more
core   +1 more source

Probing the role of Coniferin and Tetrahydrocurcumin from Traditional Chinese medicine against PSAT1 in early-stage ovarian cancer: An in silico study.

PLoS ONE
Ovarian cancer, a formidable gynaecological malignancy, poses a significant global health challenge, and it is characterised by late-stage diagnosis and a high mortality rate. Even in its early stages, when treatment choices are scarce, ovarian cancer is
Jia Zhang, Shalesh Gangwar, Nagmi Bano, Shaban Ahmad, Mohammed S Alqahtani, Khalid Raza   +5 more
doaj   +1 more source

Synthesis and characterization of l-3-(pentafluorophosphato-difluoromethyl)-alanine, a structural and functional mimetic of phosphoserine [PDF]

Serine phosphorylation is an essential switch for regulating the interactions and functions of many disease-related proteins. Accordingly, stable phosphoserine mimetics constitute chemical tools to study the effects of these post-translational ...
Tiemann, Markus, Ambros, Anna Magdalena, Limberg, Niklas, Wolber, Gerhard, Rademann, Jörg, Riedel, Sebastian, Denzinger, Katrin   +6 more
core   +1 more source

Serine biosynthetic pathway inhibitors

The present invention relates to serine biosynthetic pathway inhibitors such as phosphoglycerate dehydrogenase inhibitors and phosphoserine aminotransferase 1 inhibitors, and to theses inhibitors for use as a medicament, more in particular for the ...
Corbet, Cyril, Ravez, Séverine, Frédérick, Raphaël, Spillier, Quentin, Feron, Olivier   +4 more
core  

Phosphoserine aminotransferase SerC is a central metabolic checkpoint and druggable vulnerability in Mycobacterium tuberculosis

bioRxiv
M. J. Perret, T. Mendum, Daniel Kim, Jade Seng, Brian D. Robertson, Rebecca Winsbury, Simon Clark, J. McFadden, Khushboo Borah Slater   +8 more
semanticscholar   +1 more source

Macrophage-to-myofibroblast transition-derived itaconate promotes bone metastasis in lung cancer through targeting of HSPA8. [PDF]

Exp Mol Med
Qian J, Tan Z, Wang J, Wei T, Huang C, Cheng S, Zhong G, Zou H, Kang X, Sun L, Zhang Y.   +10 more
europepmc   +1 more source

Phosphoserine as an Alternative Energy Source for <i>E. coli</i> Cell-Free Protein Synthesis with Increased Yield and Prolonged Activity. [PDF]

ACS Synth Biol
Ackerman S, Fink Y, Habib Y, Cohen-Karni D, Adir O, Chen G, Richtman Y, Siquenique S, Levi M, Shklover J, Sarmento B, Schroeder A.   +11 more
europepmc   +1 more source

L-serine at the crossroads of microbiota, intestinal health, and disorders. [PDF]

Commun Biol
Devaux A, Boucher D, Villéger R, Bonnet M.   +3 more
europepmc   +1 more source

Coniferaldehyde Reverses PGK1-3-Phosphoglycerate-L-Serine Metabolic Reprogramming in Hindlimb Ischemia. [PDF]

Metabolites
Dong Y, Ma C, Wang X, Han J, Zhu Z, Hu S, Hu Z, Wang L.   +7 more
europepmc   +1 more source

Gut Dysbiosis Serine-Glycine Metabolism and Glioblastoma: Exploring Therapeutic Opportunities. [PDF]

Cancers (Basel)
Mangano M, Ermio MC, Sciubba F, De Rosa M, D'A Lessandro G, Limatola C, Rosito M.   +6 more
europepmc   +1 more source