Aromatic lactic acid production by <i>Bifidobacterium longum</i> subsp. <i>infantis</i> is determined by cell density, substrate availability, and pH <i>in vitro</i>. [PDF]
Plenge TG, Pedersen M, Laursen MF.
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Decoding the metabolic cipher of dormant cancer cells: molecular mechanisms and therapeutic potentials. [PDF]
Qin Y +5 more
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A PSAT1 buff of YBX1 transcriptionally sustains HLA-E-mediated evasion of NK immunity. [PDF]
Zhang Y +17 more
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Effect of rumen-protected L-tryptophan on productivity and metabolic responses in dry Holstein cows under heat stress conditions. [PDF]
Jo JH, Nejad JG, Ok MJ, Lee HG.
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Clinical variability of ATP11C-related hemolytic anemia: expanding the phenotypic and diagnostic spectrum. [PDF]
D'Onofrio V +20 more
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Accumulation of 13C-labeled phosphatidylethanolamine in the termite abdomen revealed by correlative isotope microscopy and mass microscopy. [PDF]
Ferdous R +18 more
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Glutamine metabolism remodels tumor-associated macrophage: mechanistic explorations and new strategies in translational medicine. [PDF]
Cui J, Yan X, Song J.
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Structural basis of
Phosphoserine aminotransferase is a vitamin B6-dependent enzyme that catalyzes the reversible conversion of 3-phosphohydroxypyruvate to L-phosphoserine using glutamate as an amine donor. In an effort to gain insight into the substrate-recognition mechanism of the enzyme, crystal structures of Bacillus alcalophilus phosphoserine aminotransferase in the ...
Battula, Pradeep +2 more
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Phosphoserine Aminotransferase 1: A Metabolic Enzyme Target of Cancers
Current Cancer Drug Targets, 2023Abstract: Phosphoserine aminotransferase 1 (PSAT1) catalyzes 3-phosphohydroxylpyruvate and glutamate into 3-phosphoserine and α-ketoglutamate. It integrates metabolic pathways critical for cell proliferation, survival, migration and epigenetics, such as glycolysis, de novo serine synthesis, citric acid cycle and one-carbon metabolism.
Yuping Chen
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