Results 31 to 40 of about 46,144 (173)
Endocrine Regulations, 2023 Objective. Serine synthesis as well as endoplasmic reticulum stress and hypoxia are important factors of malignant tumor growth including glioblastoma.
Sliusar Myroslava Y. +8 more
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Phosphoserine Aminotransferase in Soybean Root Nodules [PDF]
Plant Physiology, 1986 Phosphoserine aminotransferase activity was detected in the plant and bacteroid fractions from soybean (Glycine max) root nodules. Both total and specific activities increased in the plant fraction during nodule development. Serine-pyruvate aminotransferase activity was not detectable in the plant or bacteroid fractions of these nodules.
P H, Reynolds, D G, Blevins
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Expressions and roles of key enzymes in serine synthesis pathway in NaAsO2-treated HaCaT cells
环境与职业医学, 2022 BackgroundThe key enzymes of serine synthesis pathway (SSP) play an important role in tumor growth, proliferation, and invasion, but their roles in arsenic carcinogenesis are unclear.ObjectiveTo observe the effects of NaAsO2 treatment on the expressions ...
Fengmin LI +5 more
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Aryloxy Triester Phosphoramidates as Phosphoserine Biocleavable Masking Motifs [PDF]
, 2019 Many cellular protein-protein interactions (PPIs) are mediated by phosphoserine. The specific targeting of these PPIs by phosphoserine-containing small molecules has been scarce due to the dephosphorylation of phosphoserine and its charged nature at ...
Olivia A., Lambourne +6 more
core +3 more sources
[179] Phosphoserine aminotransferase (sheep brain)
Archives of Biochemistry and Biophysics, 1971 Publisher Summary This chapter focuses on Phosphoserine Aminotransferase (Sheep Brain). The chapter begins with a discussion of Assay method. Phosphohydroxypyruvate is prepared by hydrolysis of the hydroxypyruvic acid phosphate dimethylketal according to the procedure of Ballou.
Helga Hirsch-Kolb, David M. Greenberg
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Altered expression of genes involved in the serine synthesis pathway (SSP) in patients with acute myeloid leukemia [PDF]
Journal of Kerman University of Medical SciencesBackground: Acute myeloid leukemia (AML) is characterized by the uncontrolled proliferation of malignant cells, which rely on various metabolic pathways to sustain their survival and growth.
Parinaz Khadem +4 more
doaj +1 more source
Studies on Phosphoserine Aminotransferase of Sheep Brain
Journal of Biological Chemistry, 1967 Abstract Phosphoserine aminotransferase has been purified about 500-fold from sheep brain extracts by ammonium sulfate precipitation and Sephadex and diethylaminoethyl cellulose chromatography. On ultracentrifugation, the enzyme migrated in a single peak with a sedimentation constant of 4.2 S.
H, Hirsch, D M, Greenberg
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Targeting the Serine Pathway: A Promising Approach against Tuberculosis?
Pharmaceuticals, 2019 Tuberculosis is still the leading cause of death by a single infectious agent. Effective chemotherapy has been used and improved since the 1950s, but strains resistant to this therapy and most antibacterial drugs on the market are emerging.
Marie Haufroid, Johan Wouters
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NapR Regulates the Expression of Phosphoserine Aminotransferase SerC to Modulate Biofilm Formation and Resistance to Serine Stress of Mycobacteria. [PDF]
Int J Mol SciMycobacterium tuberculosis is a formidable pathogen capable of establishing persistent infections within macrophages. To survive and thrive within the host environment, it has evolved intricate regulatory networks, including a diverse array of ...
Guo M, Ling X, He L, Gou Y, Li Z, Li W.
europepmc +2 more sources
Cooperativity of Glucocorticoid Response Elements Located Far Upstream of the Tyrosine Aminotransferase Gene [PDF]
, 1987 Two glucocorticoid response elements (GREs) located 2.5 kb upstream of the transcription initiation site of the tyrosine aminotransferase gene were identified by gene transfer experiments and shown to bind to purified glucocorticoid receptor.
Strähle, Uwe +7 more
core +1 more source