Results 51 to 60 of about 46,144 (173)
Frontiers in Microbiology, 2023 IntroductionAlicyclobacillus has been isolated from extreme environments such as hot springs, volcanoes, as well as pasteurized acidic beverages, because it can tolerate extreme temperatures and acidity.
Hye Won Kim +16 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires +15 more
wiley +1 more source
Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant
Signal Transduction and Targeted Therapy, 2023 The single-nucleotide polymorphism (SNP) of p53, in particular the codon 72 variants, has recently been implicated as a critical regulator in tumor progression. However, the underlying mechanism remains elusive.
Jingwen Jiang +14 more
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Advanced Science, Volume 13, Issue 47, 24 August 2026.Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang +6 more
wiley +1 more source
Frontiers in Molecular Biosciences, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, as coronavirus disease 2019 (COVID-19) pandemic, has killed more than a million people worldwide, and researchers are constantly working to develop therapeutics in the treatment and ...
Shiv Bharadwaj +3 more
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MedComm, Volume 7, Issue 8, August 2026.Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang +3 more
wiley +1 more source
, 2023 L-serine and D-serine play crucial roles in the central nervous system (CNS). Indeed, L-serine is a neurotrophic factor and represents the precursor of the neurotransmitters glycine and D-serine, the co-agonists of N-methyl-D-aspartate (NMDA) glutamate ...
MICHIELON, ANNALISA
core
European Journal of Pain, Volume 30, Issue 6, July 2026.ABSTRACT Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway.
Nicolas Macian +8 more
wiley +1 more source
Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome
Frontiers in Molecular Biosciences, 2021 Background: Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative disorder associated with premutation CGG-repeat expansions (55–200 repeats) in the 5′ non-coding portion of the fragile X mental retardation 1 (FMR1) gene.
Katharine Nichole Holm +14 more
doaj +1 more source
PROTEOMICS, Volume 26, Issue 7, Page 146-157, July 2026.ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam +4 more
wiley +1 more source