Results 51 to 60 of about 163,724 (193)

RNA-Seq of Phenotypically Distinct Eimeria maxima Strains Reveals Coordinated and Contrasting Maturation and Shared Sporogonic Biomarkers with Eimeria acervulina

open access: yesPathogens, 2023
Strains of Eimeria maxima, an enteric parasite of poultry, vary in virulence. Here, we performed microscopy and RNA sequencing on oocysts of strains APU-1 (which exhibits more virulence) and APU-2.
Matthew S. Tucker   +5 more
doaj   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

open access: yesPest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano   +7 more
wiley   +1 more source

Genomic insight and physiological characterization of thermoacidophilic Alicyclobacillus isolated from Yellowstone National Park

open access: yesFrontiers in Microbiology, 2023
IntroductionAlicyclobacillus has been isolated from extreme environments such as hot springs, volcanoes, as well as pasteurized acidic beverages, because it can tolerate extreme temperatures and acidity.
Hye Won Kim   +16 more
doaj   +1 more source

Emerging insights into amino acid metabolism in the heart: implications for cardiovascular diseases and therapeutic targeting

open access: yesBritish Journal of Pharmacology, EarlyView.
As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam   +6 more
wiley   +1 more source

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells-3

open access: yes, 2011
Copyright information:Taken from "Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells"http://www.molecular-cancer.com/content/7/1/14Molecular Cancer 2008;7():14-14.Published ...
Céline Gongora (86934)   +12 more
core   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

open access: yesInsect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto   +2 more
wiley   +1 more source

Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant

open access: yesSignal Transduction and Targeted Therapy, 2023
The single-nucleotide polymorphism (SNP) of p53, in particular the codon 72 variants, has recently been implicated as a critical regulator in tumor progression. However, the underlying mechanism remains elusive.
Jingwen Jiang   +14 more
doaj   +1 more source

Multienzyme Cascade Reactions: Compatibility, Cooperativity, and Control

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 21, 3 November 2026.
Multienzyme cascade reactions are sequences of telescoped biotransformations that avoid the isolation of intermediates and offer significant efficiency advantages over traditional multistep routes. This review article highlights recent examples of multienzyme cascades and explores how their success depends on the consideration of compatibility ...
Isabella E. E. Kroschel   +2 more
wiley   +1 more source

Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells-4

open access: yes, 2011
Copyright information:Taken from "Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells"http://www.molecular-cancer.com/content/7/1/14Molecular Cancer 2008;7():14-14.Published ...
Céline Gongora (86934)   +12 more
core   +1 more source

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

open access: yesThe Journal of Physiology, Volume 604, Issue 20, Page 8636-8661, 15 October 2026.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires   +15 more
wiley   +1 more source

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