Results 61 to 70 of about 465,841 (199)
L-Ser supply in the central nervous system of mammals mostly relies on its endogenous biosynthesis by the phosphorylated pathway (PP). Defects in any of the three enzymes operating in the pathway result in a group of neurometabolic diseases collectively ...
Francesco Marchesani +8 more
semanticscholar +1 more source
Phosphoserine aminotransferase (PSAT) is a pyridoxal 5′-phosphate (PLP)-dependent enzyme that catalyzes the conversion of 3-phosphohydroxypyruvate (3-PHP) to 3-phosphoserine (PSer) in an L-glutamate (Glu)-linked reversible transamination reaction.
Bartosz Sekula +2 more
doaj +1 more source
Phosphorylation-dependent protein interaction with Trypanosoma brucei 14-3-3 proteins that display atypical target recognition. [PDF]
BACKGROUND: The 14-3-3 proteins are structurally conserved throughout eukaryotes and participate in protein kinase signaling. All 14-3-3 proteins are known to bind to evolutionally conserved phosphoserine-containing motifs (modes 1 and/or 2) with high ...
Masahiro Inoue +7 more
doaj +1 more source
SAV1 in Cooperation With FKBP52 Participates in Implantation
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He +7 more
wiley +1 more source
The dynamics of alkaline phosphatase activity during operculum regeneration in the polychaete Pomatoceros lamarckii [PDF]
RS is supported by a Carnegie Scholarship. Date of Acceptance: 20/06/2014Alkaline phosphatase enzymes are found throughout the living world and fulfil a variety of functions.
Ferrier, David Ellard Keith, Szabo, Reka
core +1 more source
Tropomyosins are coiled-coil proteins that regulate the stability and / or function of actin cytoskeleton in muscle and non-muscle cells through direct binding of actin filaments.
Saravanan Palani +2 more
doaj +1 more source
Action of Purified Milk Phosphatase on Phosphoserine and on Casein
Summary The action of a purified alkaline phosphatase from milk on casein and phosphoserine has been studied. The milk phosphatase preparation has no proteolytic action on casein, but it splits inorganic phosphate from both casein and phosphoserine.
C.A. Zittle, Elizabeth W. Bingham
openaire +1 more source
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang +12 more
wiley +1 more source
The Phosphohistidine Phosphatase SixA Targets a Phosphotransferase System
SixA, a well-conserved protein found in proteobacteria, actinobacteria, and cyanobacteria, is the only reported example of a bacterial phosphohistidine phosphatase. A single protein target of SixA has been reported to date: the Escherichia coli histidine
Jane E. Schulte, Mark Goulian
doaj +1 more source

