Results 11 to 20 of about 20,821 (225)
Calcium channel-dependent molecular maturation of photoreceptor synapses. [PDF]
PLoS ONE, 2013 Several studies have shown the importance of calcium channels in the development and/or maturation of synapses. The Ca(V)1.4(α(1F)) knockout mouse is a unique model to study the role of calcium channels in photoreceptor synapse formation.
Nawal Zabouri, Silke Haverkamp
doaj +5 more sources
The role of carcinine in signaling at the Drosophila photoreceptor synapse. [PDF]
PLoS Genetics, 2007 The Drosophila melanogaster photoreceptor cell has long served as a model system for researchers focusing on how animal sensory neurons receive information from their surroundings and translate this information into chemical and electrical messages ...
Brendan A Gavin +2 more
doaj +4 more sources
Coming of Age for the Photoreceptor Synapse. [PDF]
Invest Ophthalmol Vis Sci, 2021 To discuss the potential contribution of rod and cone synapses to the loss of visual function in retinal injury and disease.The published literature and the authors' own work were reviewed.Retinal detachment is used as a case study of rod spherule and cone pedicle plasticity after injury.
Townes-Anderson E +3 more
europepmc +3 more sources
The first synapse in vision in the aging mouse retina
Frontiers in Cellular Neuroscience, 2023 Vision is our primary sense, and maintaining it throughout our lifespan is crucial for our well-being. However, the retina, which initiates vision, suffers from an age-related, irreversible functional decline. What causes this functional decline, and how
Kaspar Gierke +3 more
doaj +1 more source
Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters. [PDF]
eNeuro, 2017 Photoreceptor ribbon synapses tonically release glutamate. To ensure efficient signal transmission and prevent glutamate toxicity, a highly efficient glutamate removal system provided by members of the SLC1 gene family is required. By using a combination of biophysical andin vivostudies, we elucidate the role of excitatory amino acid transporter 2 ...
Niklaus S +7 more
europepmc +4 more sources
Frontiers in Cellular Neuroscience, 2021 Synaptic signaling complexes are held together by scaffold proteins, each of which is selectively capable of interacting with a number of other proteins.
Alejandro Vila +9 more
doaj +1 more source
Quantitative analysis of synaptic release at the photoreceptor synapse. [PDF]
Biophys J, 2010 Exocytosis from the rod photoreceptor is stimulated by submicromolar Ca(2+) and exhibits an unusually shallow dependence on presynaptic Ca(2+). To provide a quantitative description of the photoreceptor Ca(2+) sensor for exocytosis, we tested a family of conventional and allosteric computational models describing the final Ca(2+)-binding steps leading ...
Duncan G +4 more
europepmc +4 more sources
Paired-Pulse Depression at Photoreceptor Synapses [PDF]
The Journal of Neuroscience, 2006 Synaptic depression produced by repetitive stimulation is likely to be particularly important in shaping responses of second-order retinal neurons at the tonically active photoreceptor synapse. We analyzed the time course and mechanisms of synaptic depression at rod and cone synapses using paired-pulse protocols involving two complementary measurements
Rabl, Katalin +2 more
openaire +3 more sources
Cells, 2022 Retinal degeneration is a common feature in peroxisomal disorders leading to blindness. Peroxisomes are present in the different cell types of the retina; however, their precise contribution to retinal integrity is still unclear.
Daniëlle Swinkels +7 more
doaj +1 more source
eLife, 2021 As neural circuits form, growing processes select the correct synaptic partners through interactions between cell surface proteins. The presence of such proteins on two neuronal processes may lead to either adhesion or repulsion; however, the ...
Jessica Douthit +5 more
doaj +1 more source